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Biomedical Engineering and Bioengineering

University of South Florida

Hypertension

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Development Of A Bipolar Radiofrequency Ablation Device For Renal Denervation, Noel Perez Jun 2021

Development Of A Bipolar Radiofrequency Ablation Device For Renal Denervation, Noel Perez

USF Tampa Graduate Theses and Dissertations

The American Heart Association (AHA) reported in March 2020, hypertension (HT) is a major risk factor for cardiovascular diseases and heart stroke. Resistant hypertension (RH) is a subset of HT and affects 11-16% of hypertensive patients. RH is diagnosed when a patient cannot achieve blood pressure control despite taking three or more medications and is a serious clinical management challenge.

Renal denervation (RD) using radiofrequency (RF) ablation is an accepted form of RH therapy. RD devices are typically delivered through femoral access into the renal artery with the assistance of a standard guided sheath. In the European Union (EU), the …