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Neurobiological Markers For Remission And Persistence Of Childhood Attention-Deficit/Hyperactivity Disorder, Yuyang Luo
Neurobiological Markers For Remission And Persistence Of Childhood Attention-Deficit/Hyperactivity Disorder, Yuyang Luo
Dissertations
Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in children. Symptoms of childhood ADHD persist into adulthood in around 65% of patients, which elevates the risk for a number of adverse outcomes, resulting in substantial individual and societal burden. A neurodevelopmental double dissociation model is proposed based on existing studies in which the early onset of childhood ADHD is suggested to associate with dysfunctional subcortical structures that remain static throughout the lifetime; while diminution of symptoms over development could link to optimal development of prefrontal cortex. Current existing studies only assess basic measures including regional brain activation …
Developmental And Sex Modulated Neurological Alterations In Autism Spectrum Disorder, Azeezat Azeez
Developmental And Sex Modulated Neurological Alterations In Autism Spectrum Disorder, Azeezat Azeez
Dissertations
Autism Spectrum Disorder (ASD) was first described in 1943 by Dr. Leo Kranner in a case study published in The Nervous Child. It is a neurodevelopment disorder, with a range of clinical symptoms. According to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), used by clinicians to diagnose mental disorders, a child needs to have persistent social deficits, language impairments, and repetitive behaviors, that cannot be explained by neurological damage or intellectual disability. It is known that children diagnosed with ASD are often are developmentally delayed therefore alterations in the typical developmental trajectory should be a major factor in …