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Biomedical Engineering and Bioengineering

California Polytechnic State University, San Luis Obispo

Theses/Dissertations

2020

Bone

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Optimal Parameter Values For Accurate And Repeatable Nanoindentation Of Human Trabecular Bone, Stephen Matthew Kmak Oct 2020

Optimal Parameter Values For Accurate And Repeatable Nanoindentation Of Human Trabecular Bone, Stephen Matthew Kmak

Master's Theses

Nanoindentation techniques have not been standardized for use on bone tissues, making comparison of bone material properties obtained via nanoindentation across studies difficult and unreliable. This study determined a set of optimal parameter values for thermal drift correction time, dwell time, and loading rate that can be used to obtain accurate and repeatable material properties from human femoral trabecular bone through experimentation and statistical analysis. All testing was conducted using a single nanoindenter on a single trabeculae, with the assumption that material properties within the individual trabeculae were internally consistent. Parameters not of interest during this study, such as ambient …