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Polyetheretherketone As A Biomaterial For Spinal Applications, Jeffrey M. Toth, Mei Wang, Bradley T. Estes, Jeffrey L. Scifert, Howard B. Seim, A. Simon Turner
Polyetheretherketone As A Biomaterial For Spinal Applications, Jeffrey M. Toth, Mei Wang, Bradley T. Estes, Jeffrey L. Scifert, Howard B. Seim, A. Simon Turner
Biomedical Engineering Faculty Research and Publications
Threaded lumbar interbody spinal fusion devices (TIBFD) made from titanium have been reported to be 90% effective for single-level lumbar interbody fusion, although radiographic determination of fusion has been intensely debated in the literature. Using blinded radiographic, biomechanic, histologic, and statistical measures, we evaluated a radiolucent polyetheretherketone (PEEK)-threaded interbody fusion device packed with autograft or rhBMP-2 on an absorbable collagen sponge in 13 sheep at 6 months. Radiographic fusion, increased spinal level biomechanical stiffness, and histologic fusion were demonstrated for the PEEK cages filled with autograft or rhBMP-2 on a collagen sponge. No device degradation or wear debris was observed. …