Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Entire DC Network
Multiphoton Microscopy And Deep Learning Neural Networks For The Automated Quantification Of In Vivo, Label-Free Optical Biomarkers Of Skin Wound Healing, Jake D. Jones
Graduate Theses and Dissertations
Non-healing ulcerative wounds that occur frequently in diseases such as diabetes are challenging to diagnose and treat due to numerous possible etiologies and the variable efficacy of wound care products. With advanced age, skin wound healing is often delayed, leaving elderly patients at high risk for developing these chronic injuries. As it is challenging to discriminate age-related delays from disease-related chronicity, there is a critical need to develop new quantitative biomarkers that are sensitive to wound status. Multiphoton microscopy (MPM) techniques are well-suited for 3D imaging of epithelia and are capable of non-invasively detecting metabolic cofactors (NADH and FAD) without …
Automated Intelligent Cueing Device To Improve Ambient Gait Behaviors For Patients With Parkinson's Disease, Nader Naghavi
Automated Intelligent Cueing Device To Improve Ambient Gait Behaviors For Patients With Parkinson's Disease, Nader Naghavi
Doctoral Dissertations
Freezing of gait (FoG) is a common motor dysfunction in individuals with Parkinson’s disease (PD). FoG impairs walking and is associated with increased fall risk. Although pharmacological treatments have shown promise during ON-medication periods, FoG remains difficult to treat during medication OFF state and in advanced stages of the disease. External cueing therapy in the forms of visual, auditory, and vibrotactile, has been effective in treating gait deviations. Intelligent (or on-demand) cueing devices are novel systems that analyze gait patterns in real-time and activate cues only at moments when specific gait alterations are detected. In this study we developed methods …