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Effects Of Ketamine On Alcohol-Withdrawal Induced Behavioral Depression, Christie Edwards May 2014

Effects Of Ketamine On Alcohol-Withdrawal Induced Behavioral Depression, Christie Edwards

Honors College

The focus of this experiment was to test the possible anti-depressant effects of ketamine in a novel model of alcohol withdrawal-induced depression in mice. In this model, inbred mice show long-term strain-dependent reductions in locomotor (running wheel) activity after chronic intermittent ethanol exposure via vapor chambers. Since wheel-running is rewarding and has antidepressant effects, we believe that reduced locomotion following ethanol withdrawal may reflect a depression-like syndrome resembling that seen in many abstinent alcoholics. Nevertheless, in a previous experiment we were unable to reverse this locomotor deficit using Desipramine, a norepinephrine-selective reuptake inhibitor with behavioral activating properties. Since low-dose ketamine …


Genetic Engineering, A Hope For Sustainable Biofuel Production: Review, Sudip Paudel, Michael A. Menze Jan 2014

Genetic Engineering, A Hope For Sustainable Biofuel Production: Review, Sudip Paudel, Michael A. Menze

Michael Menze

The use of recently developed genetic engineering tools in combination with organisms that have the potential to produce precursors for the production of biodiesel, promises a sustainable and environment friendly energy source. Enhanced lipid production in wild type and/or genetically engineered organisms can offer sufficient raw material for industrial transesterification of plant-based triglycerides. Bio-diesel, produced with the help of genetically modified organisms, might be one of the best alternatives to fossil fuels and to mitigate various environmental hazards.


Genetic Engineering, A Hope For Sustainable Biofuel Production : Review., Sudip Paudel, Michael Menze Jan 2014

Genetic Engineering, A Hope For Sustainable Biofuel Production : Review., Sudip Paudel, Michael Menze

Faculty Scholarship

The use of recently developed genetic engineering tools in combination with organisms that have the potential to produce precursors for the production of biodiesel, promises a sustainable and environment friendly energy source. Enhanced lipid production in wild type and/or genetically engineered organisms can offer sufficient raw material for industrial transesterification of plant-based triglycerides. Bio-diesel, produced with the help of genetically modified organisms, might be one of the best alternatives to fossil fuels and to mitigate various environmental hazards.


Genetic Engineering, A Hope For Sustainable Biofuel Production: Review, Sudip Paudel, Michael A. Menze Jan 2014

Genetic Engineering, A Hope For Sustainable Biofuel Production: Review, Sudip Paudel, Michael A. Menze

Faculty Research & Creative Activity

The use of recently developed genetic engineering tools in combination with organisms that have the potential to produce precursors for the production of biodiesel, promises a sustainable and environment friendly energy source. Enhanced lipid production in wild type and/or genetically engineered organisms can offer sufficient raw material for industrial transesterification of plant-based triglycerides. Bio-diesel, produced with the help of genetically modified organisms, might be one of the best alternatives to fossil fuels and to mitigate various environmental hazards.