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Immunological Tradeoffs And The Impacts Of Urbanization On The Reproductive Ecology And Physiology Of The Side-Blotched Lizard (Uta Stansburiana), Emily E. Virgin Dec 2022

Immunological Tradeoffs And The Impacts Of Urbanization On The Reproductive Ecology And Physiology Of The Side-Blotched Lizard (Uta Stansburiana), Emily E. Virgin

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Investing resources into reproduction can limit energy available to other competing demands, such as fighting off an infection; yet, both processes are necessary for organisms to survive and pass on their genes to the next generation. These strategies often follow patterns associated with lifespan, such that shorter-lived animals are more likely to invest more resources into reproduction over survival, and vice versa in long-lived animals. However, environmental change caused by urbanization can disrupt these relationships, and the within- and transgenerational costs of urbanization on females and offspring are unknown. I address these uncertainties in three research chapters to better understand …


Effects Of Ahcc On The Interaction Between T And B Lymphocytes, Sajina Poudel Aug 2022

Effects Of Ahcc On The Interaction Between T And B Lymphocytes, Sajina Poudel

Theses (2016-Present)

AHCC is a beta-glucan derived from the shiitake mushroom. It is used as an immune supplement and is known to boost the immune system. The mechanisms involved are increased lymphocyte proliferation and reduction of inflammation. The effects have been well studied in T cells. However, factors produced by T cells that affect B cells have not been studied. In this study, we explored the gene products stimulated by the AHCC exposure in T lymphocytes which play a role in B cell function. Data from a prior gene array experiment were used to delineate the effects of AHCC on the interaction …


Anxiety And Immunity: Affecting The Body And The Mind, Katelynn Dobbs May 2022

Anxiety And Immunity: Affecting The Body And The Mind, Katelynn Dobbs

Theses/Capstones/Creative Projects

Speculations have been made within the scientific community that there is a link between the underlying mechanisms that impact anxiety disorders and immune system disorders. While many correlations between these disorders have been observed through various immune system disorder studies, this subject is still severely under-explored. In order to examine the potential relationship between anxiety disorders and immune system disorders, a survey was conducted and distributed among the student population at the University of Nebraska at Omaha. This survey collected data by asking a variety of questions that pertained to anxiety and immune system disorders diagnoses within the student population …


Hemocyte-Mediated Immune Response To A Bacterial Infection In The Cat Flea (Ctenocephalides Felis), Melanie Muñoz Jan 2022

Hemocyte-Mediated Immune Response To A Bacterial Infection In The Cat Flea (Ctenocephalides Felis), Melanie Muñoz

Electronic Theses and Dissertations

Despite their continued medical and veterinary importance, the vectorial capacity of fleas (Order Siphonaptera) is often underestimated. Fleas are best described as ectoparasites of a variety of mammalian and aviary hosts. In humans, fleas are infamous for the transmission of several detrimental agents, including those that cause plague, murine typhus, and cat-scratch disease. Although their significance in flea immune responses remains unknown, phagocytic immune cells, known as hemocytes, are important players in the cell mediated immune response of insects. Among invertebrates, hemocytes provide defense against foreign microbes via phagocytosis, cellular encapsulation, and the production of humoral immune factors. As mentioned …