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Temporal Dynamics And Spatial Analysis Of Competing Dengue 2 Virus Strains In The Americas, Stacy O'Neil Scholle

Biology ETDs

The dengue virus is the causative agent of an important re-emerging infectious disease that has become increasingly significant in tropical America and the Caribbean due to the infiltration of a more pathogenic Asian/American strain of dengue serotype 2 into the population. This invading strain is responsible for epidemics of dengue hemorrhagic fever, a life-threatening disease that was not previously a large public health concern in the region. Here, I create a historical map of the invasion and replacement of the endemic American strain of dengue 2 by the Asian/American strain, showing that the timing of invasion spans 25 years, and …