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Biology

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Biofilm

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The Role Cranberry Proanthocyanidins Play In The Primary Attachment Of Bacteria To Surfaces: Bacillus Cereus Model, Anthony Robert Jones Nov 2008

The Role Cranberry Proanthocyanidins Play In The Primary Attachment Of Bacteria To Surfaces: Bacillus Cereus Model, Anthony Robert Jones

Biology Dissertations

The development of a proanthocyanidin (PAC) treatment, along with the understanding of its mechanism of action, would provide an alternative method of preventing attachment to and colonization of surfaces by microorganisms, as well as potentially disrupting preexisting biofilms. The purpose of this research is to examine the role a cranberry proanthocyanidin plays in the primary attachment of Bacillus cereus to an abiotic surface. This technology could be employed in food processing plants where a premium is placed on maintaining a sanitized work environment to prevent product contamination. A biofilm assay showed that a surface treated with proanthocyanidins actually promoted rather …


The Role Of Autoinducer-2 In Escherichia Coli Biofilm Formation And The Discovery Of A Plant-Derived Quorum Sensing Inhibitor, Chen Niu May 2006

The Role Of Autoinducer-2 In Escherichia Coli Biofilm Formation And The Discovery Of A Plant-Derived Quorum Sensing Inhibitor, Chen Niu

Biology Dissertations

The objectives of this work are: 1) to determine whether plant essential oil components influence the ability of Escherichia coli and several Pseudomonas species to form biofilms, and inhibit bacterial quorum sensing; 2) to understand the role of autoinducer-2 (AI-2) in biofilm formation by E. coli W3110. The biofilm formation assays determined that cinnamon, cassia and citronella oils differentially affected growth-normalized biofilm formation by E. coli. Cinnamaldehyde (CA) also inhibited the swimming motility of E. coli. Subinhibitory concentrations of CA were effective at inhibiting two types of acyl homoserine lactone (HSL) mediated quorum sensing (QS), and also AI-2 mediated QS. …