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Shifts In Metabolic Demands In Growing Altricial Nestlings Illustrate Context-Specific Relationships Between Basal Metabolic Rate And Body Composition, Fraņois Vézina, Oliver P. Love, Mylaine Lessard, Tony D. Williams
Shifts In Metabolic Demands In Growing Altricial Nestlings Illustrate Context-Specific Relationships Between Basal Metabolic Rate And Body Composition, Fraņois Vézina, Oliver P. Love, Mylaine Lessard, Tony D. Williams
Integrative Biology Publications
Basal metabolic rate (BMR) in animals is interpreted as reflecting the size and metabolic intensity of energy-consuming tissues. However, studies investigating relationships between the mass of specific organs and interindividual variation in BMR have produced inconsistent patterns with regard to which organs have the largest impact on BMR variation. Because of the known flexibility in organ mass and metabolic intensity within individual organs, relationships between BMR and body- composition variables are bound to be context specific. Altricial nestlings are excellent models to illustrate this phenomenon because of the extreme variation in body composition occurring during growth. Using European starlings at …
Juveniles Exposed To Embryonic Corticosterone Have Enhanced Flight Performance, Eunice H. Chin, Oliver P. Love, Jan J. Verspoor, Tony D. Williams, Kyle Rowley, Gary Burness
Juveniles Exposed To Embryonic Corticosterone Have Enhanced Flight Performance, Eunice H. Chin, Oliver P. Love, Jan J. Verspoor, Tony D. Williams, Kyle Rowley, Gary Burness
Integrative Biology Publications
Exposure to maternally derived glucocorticoids during embryonic development impacts offspring phenotype. Although many of these effects appear to be transiently 'negative', embryonic exposure to maternally derived stress hormones is hypothesized to induce preparative responses that increase survival prospects for offspring in low-quality environments; however, little is known about how maternal stress influences longer-term survival-related performance traits in free-living individuals. Using an experimental elevation of yolk corticosterone (embryonic signal of low maternal quality), we examined potential impacts of embryonic exposure to maternally derived stress on flight performance, wing loading, muscle morphology and muscle physiology in juvenile European starlings (Sturnus vulgaris). Here …
Development Of Ecological Indicators For The U.S. Great Lakes Coastal Region – A Summary Of Applications In Lake Huron, Gerald J. Niemi, Valerie J. Brady, Terry N. Brown, Jan J.H. Ciborowski, Nicholas P. Danz, Dana M. Ghioca, Joann M. Hanowski, Tom P. Hollenhorst, Robert W. Howe, Lucinda B. Johnson., Carol A. Johnston, Euan D. Reavie
Development Of Ecological Indicators For The U.S. Great Lakes Coastal Region – A Summary Of Applications In Lake Huron, Gerald J. Niemi, Valerie J. Brady, Terry N. Brown, Jan J.H. Ciborowski, Nicholas P. Danz, Dana M. Ghioca, Joann M. Hanowski, Tom P. Hollenhorst, Robert W. Howe, Lucinda B. Johnson., Carol A. Johnston, Euan D. Reavie
Biological Sciences Publications
No abstract provided.
Gene Expression Patterns In Heterozygous Plk4 Murine Embryonic Fibroblasts, Alan Morettin, Alejandra Ward, Nantais, Jordan Nantais, Jordan, John W. Hudson
Gene Expression Patterns In Heterozygous Plk4 Murine Embryonic Fibroblasts, Alan Morettin, Alejandra Ward, Nantais, Jordan Nantais, Jordan, John W. Hudson
Biological Sciences Publications
The polo-like kinases (Plks) are a group of serine/threonine kinases which have roles in many aspects of cellular function including the regulation of mitotic activity and cellular stress responses. This study focuses on Plk4, the most divergent member of the Plk family, which is necessary for proper cellular proliferation. More specifically, alterations in Plk4 levels cause significantly adverse mitotic defects including abnormal centrosome duplication and aberrant mitotic spindle formation. We sought to clarify the effect of reduced Plk4 levels on the cell by examining transcript profiles of Plk4 wild-type and heterozygous mouse embryonic fibroblasts (MEFs). Subsequently, the levels of several …
Shifts In Metabolic Demands In Growing Altricial Nestlings Illustrate Context-Specific Relationships Between Basal Metabolic Rate And Body Composition, Francois Vezina, Oliver P. Love, Mylaine Lessard, Tony D. Williams
Shifts In Metabolic Demands In Growing Altricial Nestlings Illustrate Context-Specific Relationships Between Basal Metabolic Rate And Body Composition, Francois Vezina, Oliver P. Love, Mylaine Lessard, Tony D. Williams
Biological Sciences Publications
Basal metabolic rate (BMR) in animals is interpreted as reflecting the size and metabolic intensity of energy-consuming tissues. However, studies investigating relationships between the mass of specific organs and interindividual variation in BMR have produced inconsistent patterns with regard to which organs have the largest impact on BMR variation. Because of the known flexibility in organ mass and metabolic intensity within individual organs, relationships between BMR and body-composition variables are bound to be context specific. Altricial nestlings are excellent models to illustrate this phenomenon because of the extreme variation in body composition occurring during growth. Using European starlings at three …
The Condition Conundrum: Application Of Multiple Condition Indices To The Dusky Shark Carcharhinus Obscurus, N. E. Hussey, D. T. Cocks, Dudley, S.F.J. Dudley, S.F.J., I. D. Mccarthy, S. P. Wintner
The Condition Conundrum: Application Of Multiple Condition Indices To The Dusky Shark Carcharhinus Obscurus, N. E. Hussey, D. T. Cocks, Dudley, S.F.J. Dudley, S.F.J., I. D. Mccarthy, S. P. Wintner
Biological Sciences Publications
No abstract provided.
Expression Of Cap2 During Early Xenopus Embryogenesis, Marian Wolanski, Farhad Khosrowshahian, L Jerant, Ing-Suan Jap
Expression Of Cap2 During Early Xenopus Embryogenesis, Marian Wolanski, Farhad Khosrowshahian, L Jerant, Ing-Suan Jap
Biological Sciences Publications
We have cloned and characterized a second member of the Xenopus CAP (cyclase associated protein) gene family. xCAP2 demonstrates greater restriction of expression than its homolog, xCAP1, and is differentially expressed throughout early embryogenesis. Although present as a maternal transcript, CAP2 comes to be expressed in the anterior-most mesoderm/endoderm during late gastrulation, in paraxial mesoderm during late neurula stages, and later expresses in lens, cardiac primordia, somites, otic vesicles, retina,and in the optic and craniofacial musculature. The gene is also expressed in the leading edge of myotome.
Xarx2: An Aristaless Homolog That Regulates Brain Regionalization During Development In Xenopus Laevis, Marian Wolanski, Farhad Khosrowshahian, Le Kelly, Michael J. Crawford
Xarx2: An Aristaless Homolog That Regulates Brain Regionalization During Development In Xenopus Laevis, Marian Wolanski, Farhad Khosrowshahian, Le Kelly, Michael J. Crawford
Biological Sciences Publications
The aristaless-related gene, Arx, plays a fundamental role in patterning the brain in humans and mice. Arx mutants exhibit lissencephaly among other anomalies. We have cloned a Xenopus aristaless homolog that appears to define specific regions of the developing forebrain. xArx2 is transcribed in blastula through neurula stages, and comes to be restricted to the ventra and lateral telencephalon, lateral diencephalon, neural floor plate of the anterior spinal cord, and somites. In this respect, Arx2 expresses in regions similar to Arx with the exception of the somites. Overexpression enlarges the telencephalon, and interference by means of antisense morpholino-mediated translation knockdown …
The Cyclin-Dependent Kinase Activator, Spy1a, Is Targeted For Degradation By The Ubiquitin Ligase Nedd4, Mohammad Al Sorkhy, Ryan Craig, Brenna Market, Ryan Ard, Lisa A. Porter
The Cyclin-Dependent Kinase Activator, Spy1a, Is Targeted For Degradation By The Ubiquitin Ligase Nedd4, Mohammad Al Sorkhy, Ryan Craig, Brenna Market, Ryan Ard, Lisa A. Porter
Biological Sciences Publications
Spy1A is a cyclin-like protein required for progression through the G(1)/S phase of the cell cycle. Elevated Spy1A protein levels have been implicated in tumorigenesis and are attributed to overriding the DNA damage response and enhancing cell proliferation. Understanding how Spy1A is produced and degraded is essential in resolving how it contributes to normal and abnormal growth processes. Herein, we demonstrate that Spy1A is degraded in a cell cycle-dependent manner during mitosis via the ubiquitin-proteasome system. We have resolved the E3 ligase and essential phosphorylation sites mediating Spy1A degradation. Furthermore, we have determined that non-degradable forms of Spy1A do not …