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Biology

University of South Carolina

Theses and Dissertations

Theses/Dissertations

Gene

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From Gene Expression To Physiology: A Study Of Chronic Thermal Tolerance In The Mytilus Edulis Species Complex, Lindsey Cate Schwartz Apr 2022

From Gene Expression To Physiology: A Study Of Chronic Thermal Tolerance In The Mytilus Edulis Species Complex, Lindsey Cate Schwartz

Theses and Dissertations

Rising ocean temperatures are a severe and ever-present threat to marine life. With environmental temperature having such a large impact on organismal performance, understanding the mechanisms which contribute to the ability to survive at higher temperatures is a crucial research focus. Significant progress has been made in discovering these mechanisms on the cellular, biochemical, and physiological levels, but is it much less common for those to be examined together. Using the Mytilus edulisspecies complex as a model system, this dissertation takes a closer look at how prolonged exposure to sub-lethal high temperatures impacts marine organisms on multiple levels of …


Identifying And Characterizing Transgenic Lines That Drive Gene Expression In The Adult Fat Body Of The Drosophila Melanogaster, Michael Edward Meyerink Apr 2020

Identifying And Characterizing Transgenic Lines That Drive Gene Expression In The Adult Fat Body Of The Drosophila Melanogaster, Michael Edward Meyerink

Theses and Dissertations

Adult Drosophila Melanogaster is a powerful model organism in genetic studies and has high tissue and gene homology to humans. Like humans, Drosophila tissues communicate in order to respond to physiological stimuli, such as diet, aging, and disease. The fat body, homologous to human adipocytes and hepatocytes, functions as both an endocrine and energy storage organ; and has been shown to play a critical role in many metabolic processes. The aim of this study is to characterize differences in fat body gene expression to ultimately identify if there are subpopulations of adipocytes with different functions related to fat body communication …