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Regulators Of Repo: A Search For Gcm/Repo Transcription Factors, Kathy Ann Nipper
Regulators Of Repo: A Search For Gcm/Repo Transcription Factors, Kathy Ann Nipper
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The role of the Drosophila melanogaster gene glial cells missing (gcm) is that of a binary switch in both the central nervous system (CNS) and the peripheral nervous system (PNS) in specification of the glial fate for multipotent precursor cells. However, Gcm is also essential for maturation of hematocytes and tendon cells ( Alfonso and Jones, 2002; Jones, et al., 1995; Hosoya et al., 1995; Soustell et al., 2004). The varied outcomes of gcm expression imply the interaction of co-factors capable of giving the Gcm protein different "meanings" in different developmental contexts. The Gcm target repo is expressed exclusively in …