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Analysis Of The Effects Of Chromatin Modifying Complexes On The Transcription Of Retrotransposon Ty2-917 In Saccharomyces Cerevisiae, Sezai̇ Türkel, Bükay Yeni̇ce
Analysis Of The Effects Of Chromatin Modifying Complexes On The Transcription Of Retrotransposon Ty2-917 In Saccharomyces Cerevisiae, Sezai̇ Türkel, Bükay Yeni̇ce
Turkish Journal of Biology
Transcription of the yeast retrotransposon Ty2-917 is regulated by a complex set of regulatory regions located both upstream and downstream of the transcription initiation site. In this study, it was found that certain chromatin modifying factors are essential for the transcriptional regulation of Ty2-917. Among the chromatin binding factors tested in this research, non-histone proteins Nhp6A/B have the largest effect on the transcription of Ty2-917. In Dnhp6A/B double mutant yeast strain transcription of Ty2 decreased 20-fold, indicating that these non-histone proteins are essential for the transcription of Ty2-917. Furthermore, it was also shown that the transcription of Ty2-917 decreased by …