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Heart Development, Coronary Vascularization And Ventricular Maturation In A Giant Danio (Devario Malabaricus), Pascal J. Lafontant, Olubusola Shifatu, Sarah Glasshagel-Chilson, Purva Patel, Wendy Tomamichel, Clay Higginbotham, Paula K. Evans, Hannah M. Nelson

Biology Faculty publications

Giant danios (genus Devario), like zebrafish, are teleosts belonging to the danioninae subfamily of cyprinids. Adult giant danios are used in a variety of investigations aimed at understanding cellular and physiological processes, including heart regeneration. Despite their importance, little is known about development and growth in giant danios, or their cardiac and coronary vessels development. To address this scarcity of knowledge, we performed a systematic study of a giant danio (Devario malabaricus), focusing on its cardiac development, from the segmentation period to ten months post-fertilization. Using light and scanning electron microscopy, we documented that its cardiovascular development and maturation proceed …