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Arsenic Affects Muscle Development And Structure In Fundulus Heteroclitus, Angela D'Amico
Arsenic Affects Muscle Development And Structure In Fundulus Heteroclitus, Angela D'Amico
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Arsenic is a naturally occurring metalloid that can enter rivers and ground water. Epidemiological studies have correlated arsenic exposure with adverse developmental outcomes such as low birth weight, delays in the use of musculature, and altered locomotor activity. Previously in our lab, embryonically exposed killifish (Fundulus heteroclitus) were found to have changes in muscle development. Microarray analysis showed several genes involved in muscle development and formation altered and histological analysis showed an increase in small muscle fiber size. In this study, killifish were used to help understand if changes in muscle formation and fiber density after embryonic exposure persist, are …
Predicting The Physiological Performance Of Ectotherms In Fluctuating Thermal Environments, Michael W. Sears, A C. Niehaus, M J. Angilletta, C E. Franklin, R S. Wilson
Predicting The Physiological Performance Of Ectotherms In Fluctuating Thermal Environments, Michael W. Sears, A C. Niehaus, M J. Angilletta, C E. Franklin, R S. Wilson
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Physiological ecologists have long sought to understand the plasticity of organisms in environments that vary widely among years, seasons and even hours. This is now even more important because human-induced climate change is predicted to affect both the mean and variability of the thermal environment. Although environmental change occurs ubiquitously, relatively few researchers have studied the effects of fluctuating environments on the performance of developing organisms. Even fewer have tried to validate a framework for predicting performance in fluctuating environments. Here, we determined whether reaction norms based on performance at constant temperatures (18, 22, 26, 30 and 34°C) could be …