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University of Central Florida

Electronic Theses and Dissertations

Theses/Dissertations

2016

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Habitat Distribution And Abundance Of Crayfishes In Two Florida Spring-Fed Rivers, Tiffani Manteuffel Jan 2016

Habitat Distribution And Abundance Of Crayfishes In Two Florida Spring-Fed Rivers, Tiffani Manteuffel

Electronic Theses and Dissertations

Crayfish are an economically and ecologically important invertebrate, however, research on crayfish in native habitats is patchy at best, including in Florida, even though the Southeastern U.S. is one of the most speciose areas globally. This study investigated patterns of abundance and habitat distribution of two crayfishes (Procambarus paeninsulanus and P. fallax) in two Florida spring-fed rivers (Wakulla River and Silver River, respectively). Study sites were surveyed once each season from April 2015 to March 2016 with baited minnow traps checked every other day, four times each survey. Habitat and environmental parameters evaluated included dominant vegetation or bottom type, percent …


Pyroglutamylated Amyloid Beta Peptides Enhance Non-Fibrillogenic Aggregation Of The Unmodified Peptide, Gregory Goldblatt Jan 2016

Pyroglutamylated Amyloid Beta Peptides Enhance Non-Fibrillogenic Aggregation Of The Unmodified Peptide, Gregory Goldblatt

Electronic Theses and Dissertations

Alzheimer's disease (AD) is accompanied by abnormal extracellular deposition of amyloid b (Ab) peptide. This has led to the amyloid cascade hypothesis, causatively relating Ab with AD. While Ab deposits assume a fibrillar cross-b structure, prefibrillar oligomers of Ab have been identified as the main cytotoxic agents in AD. Pyroglutamylated amyloid beta (AbpE) peptides are N-terminally truncated and pyroglutamylated (at Glu3 or Glu11) Ab molecules that display enhanced cytotoxicity and represent up to 50% of total Ab in AD brains. AbpE significantly enhances the toxicity of unmodified Ab by an unknown mechanism. Although in situ Ab populations are heterogeneous, the …


Assessment Of Staphylococcus Aureus Genetics: Clinical Versus Community Epidemiology, Matthew Lawrance Jan 2016

Assessment Of Staphylococcus Aureus Genetics: Clinical Versus Community Epidemiology, Matthew Lawrance

Electronic Theses and Dissertations

Staphylococcus aureus has an historical relationship with anthropogenic environments, particularly hospitals, where infection characteristics differ from community-acquired disease. This has promoted a designation of strains as healthcare or community associated. Despite this affiliation, genetic approaches have failed to support these groupings. In order to establish the genetic relationship between S. aureus from differing anthropogenic environments, I have analyzed the relatedness between three cohorts of S. aureus: nasal carriage isolates from community participants, infectious isolates from hospitals, and a cohort from an uninvestigated environment, an ambulatory clinic. Multilocus Sequence Typing (MLST) and Staphylococcus aureus protein a (spa) repeat regions were analyzed …


Transforming The Aquatic Urban Landscape: Nutrient Status And Management Of Stormwater Basins, Lindsay Skovira Jan 2016

Transforming The Aquatic Urban Landscape: Nutrient Status And Management Of Stormwater Basins, Lindsay Skovira

Electronic Theses and Dissertations

Urbanization is a largely irreversible anthropogenic change that degrades environmental quality, including aquatic ecosystems. Stormwater ponds are a popular best management practice (BMP) to mitigate the effects of urban land use on downstream water bodies and contribute significantly to the total area of aquatic ecosystems in some urban watersheds. My research investigated the distribution of stormwater ponds and examined how different urban land uses influenced biophysicochemical conditions and management of those ponds in a rapidly developing suburban watershed in the Econlockhatchee River basin in Florida, USA. I evaluated limnological and ecological parameters in randomly-selected ponds distributed among three urban land-use …


Role Of Kruppel-Like Factor 8 (Klf8) In Cancer And Cardiomyopathy, Satadru Lahiri Jan 2016

Role Of Kruppel-Like Factor 8 (Klf8) In Cancer And Cardiomyopathy, Satadru Lahiri

Electronic Theses and Dissertations

Cancer and cardiovascular diseases are two most fatal diseases causing innumerable death each year. Understanding the mechanisms underlying these diseases is critical for developing proper therapeutic approach. Kruppel-like factor 8 (KLF8) is a member of Kruppel-like family transcription factors that is overexpressed in many types of cancers. There is no report on role of KLF8 in cardiovascular diseases to date. KLF8 transcriptionally activates or represses a host of target genes to promote cancer cell proliferation, migration, invasion and epithelial to mesenchymal transition during tumor progression. Studies proposed in this thesis identified a novel posttranslational modification of KLF8 essential for its …


Involvement Of Mirnas In The Development Of Androgen Independent Prostate Cancer, Richard Ottman Jan 2016

Involvement Of Mirnas In The Development Of Androgen Independent Prostate Cancer, Richard Ottman

Electronic Theses and Dissertations

Development of resistance to androgen deprivation therapy (ADT) is a major obstacle for the management of advanced prostate cancer. Therapies with androgen receptor (AR) antagonists and androgen withdrawal initially result in tumor regression but development of compensatory mechanisms including AR bypass signaling leads to tumor re-growth, independent of circulating androgens. The result is the emergence of castration resistant prostate cancer (CRPC), a highly morbid disease exhibiting aberrant expression of many protein-coding and non-coding genes. Under the umbrella of non-coding RNAs is a class of small regulatory RNAs referred to as microRNAs (miRNAs). MicroRNAs are believed to function in the maintenance …


Flying Under The Lidar: Relating Forest Structure To Bat Community Diversity, Anna Schneider Swanson Jan 2016

Flying Under The Lidar: Relating Forest Structure To Bat Community Diversity, Anna Schneider Swanson

Electronic Theses and Dissertations

Bats are important to many ecological processes such as pollination, insect (and by proxy, disease) control, and seed dispersal and can be used to monitor ecosystem health. However, they are facing unprecedented extinction risks from habitat degradation as well as pressures from pathogens (e.g., white-nose syndrome) and wind turbines. LiDAR allows ecologists to measure structural variables of forested landscapes with increased precision and accuracy at broader spatial scales than previously possible. This study used airborne LiDAR to classify forest habitat/canopy structure at the Ordway-Swisher Biological Station (OSBS) in north central Florida. LiDAR data were acquired by the National Ecological Observatory …


Pasture Management, The Red Imported Fire Ant (Solenopsis Invicta) And Dung Beetle Mediated Ecosystem Services, Christen Steele Jan 2016

Pasture Management, The Red Imported Fire Ant (Solenopsis Invicta) And Dung Beetle Mediated Ecosystem Services, Christen Steele

Electronic Theses and Dissertations

Grazing animals in Florida deposit over 20 million metric tons of dung per year, making dung a significant non-point source of pollution (extrapolated from Fincher, 1981). Degradation of this dung occurs naturally, primarily due to a diverse group of beetles (Order Coleoptera) primarily in the families Scarabaeidae and Geotrupidae(hereafter dung beetles). Dung that is not degraded becomes a non-point source of pollutants and may be leached into water bodies. Additionally, dung provides an incubation site for the pests and parasites of both humans and livestock. Thus, as dung beetles consume and degrade dung, they provide a multitude of ecosystem services …


From Pet To Pest? The Potential Global Range And Food Web Effects Of A Generalist Carnivore, Hannah Bevan Jan 2016

From Pet To Pest? The Potential Global Range And Food Web Effects Of A Generalist Carnivore, Hannah Bevan

Electronic Theses and Dissertations

The Nile monitor lizard [Varanus niloticus (Linnaeus, 1766)] is a generalist carnivore, native to Sub-Saharan Africa and the Nile River but now established in North America as a result of the pet trade. Once introduced, they are a potential invasive threat to native wildlife. Here, I create ensemble species distribution models (SDMs) to predict the global distribution of this generalist carnivore given current and future climate conditions. I then quantify the monitor's potential effects on 85 food webs representing >900 different species within the projected regions based on stomach content data. Climate, vegetation, and elevation data are used for 507 …


Effects Of Harmful Algal Blooms Caused By Aureoumbra Lagunensis (Brown Tide) On Larval And Juvenile Life Stages Of The Eastern Oyster (Crassostrea Virginica), Panagiota Makris Jan 2016

Effects Of Harmful Algal Blooms Caused By Aureoumbra Lagunensis (Brown Tide) On Larval And Juvenile Life Stages Of The Eastern Oyster (Crassostrea Virginica), Panagiota Makris

Electronic Theses and Dissertations

Harmful algal blooms caused by the marine microalga Aureoumbra lagunensis have been associated with negative impacts on marine fauna, both vertebrate and invertebrate. Within the Indian River Lagoon (IRL) estuary system along Florida's east coast, blooms of A. lagunensis in excess of 1×106 cells mL-1 have occurred along with higher than average salinities (> 35 PSU) during times of peak reproduction and growth for the eastern oyster Crassostrea virginica. Field and laboratory studies were used to investigate the effects of A. lagunensis and high salinities on early life stages of eastern oysters, late pediveliger to early juvenile. Natural recruitment of …