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Genetic And Environmental Influences On Stomates Of Big Bluestem (Andropogon Gerardii), Nick A. Varvel, Christina J. Hilt, Loretta C. Johnson, Matthew Galliart, Sara G. Baer, Brian R. Maricle Ph.D. Nov 2018

Genetic And Environmental Influences On Stomates Of Big Bluestem (Andropogon Gerardii), Nick A. Varvel, Christina J. Hilt, Loretta C. Johnson, Matthew Galliart, Sara G. Baer, Brian R. Maricle Ph.D.

Biological Sciences Faculty Publications

Big bluestem (Andropogon gerardii) is a dominant C4 prairie grass that has wide distribution and several genetically distinct ecotypes. Many of the ecotypic adaptations are related to water availability in the native environment. Stomates facilitate photosynthetic gas exchange and regulate water loss from the plant. As such, stomatal size and density represent possible adaptations to conserve water. We hypothesized drought-tolerant ecotypes of big bluestem would have fewer or smaller stomates compared to more mesic ecotypes. Five ecotypes of big bluestem were planted in four common gardens from western Kansas to southern Illinois, USA to determine genetic and environmental influences on …


Anti-Apoptotic Effects Of Human Placental Hydrolysate Against Hepatocyte Toxicity In Vivo And In Vitro, Dong Ho Bak, Jungtae Na, Mi Ji Choi, Byung Chul Lee, Chang Taek Oh, Jeom Yong Kim, Hae Jung Han, Moo Joong Kim, Tae Ho Kim, Beom Joon Kim Nov 2018

Anti-Apoptotic Effects Of Human Placental Hydrolysate Against Hepatocyte Toxicity In Vivo And In Vitro, Dong Ho Bak, Jungtae Na, Mi Ji Choi, Byung Chul Lee, Chang Taek Oh, Jeom Yong Kim, Hae Jung Han, Moo Joong Kim, Tae Ho Kim, Beom Joon Kim

Biological Sciences Faculty Publications

Apoptosis and oxidative stress are essential for the pathogenesis of acute liver failure and fulminant hepatic failure. Human placental hydrolysate (hPH) has been reported to possess antioxidant and anti-inflammatory properties. In the present study, the protective effects of hPH against D-galactosamine (D-GalN)- and lipopolysaccharide (LPS)-induced hepatocyte apoptosis were investigated in vivo. In addition, the molecular mechanisms underlying the anti-apoptotic activities of hPH against D-GalN-induced cell death in vitro were examined. Male Sprague-D awley rats were injected with D-GaIN/LPS with or without the administration of hPH. Rats were sacrificed 24 h after D-GaIN/LPS intraperitoneal injection, and the blood and liver samples …


Human Umbilical Cord Blood Mesenchymal Stem Cells Engineered To Overexpress Growth Factors Accelerate Outcomes In Hair Growth, Dong Ho Bak, Mi Ji Choi, Soon Re Kim, Byung Chul Lee, Jae Min Kim, Eun Su Jeon, Wonil Oh, Ee Seok Lim, Byung Cheol Park, Moo Joong Kim, Jungtae Na, Beom Joon Kim Aug 2018

Human Umbilical Cord Blood Mesenchymal Stem Cells Engineered To Overexpress Growth Factors Accelerate Outcomes In Hair Growth, Dong Ho Bak, Mi Ji Choi, Soon Re Kim, Byung Chul Lee, Jae Min Kim, Eun Su Jeon, Wonil Oh, Ee Seok Lim, Byung Cheol Park, Moo Joong Kim, Jungtae Na, Beom Joon Kim

Biological Sciences Faculty Publications

Human umbilical cord blood mesenchymal stem cells (hUCB-MSCs) are used in tissue repair and regeneration; however, the mechanisms involved are not well understood. We investigated the hair growth-promoting effects of hUCB-MSCs treatment to determine whether hUCB-MSCs enhance the promotion of hair growth. Furthermore, we attempted to identify the factors responsible for hair growth. The effects of hUCB-MSCs on hair growth were investigated in vivo, and hUCB-MSCs advanced anagen onset and hair follicle neogeneration. We found that hUCB-MSCs co-culture increased the viability and up-regulated hair induction-related proteins of human dermal papilla cells (hDPCs) in vitro. A growth factor antibody array revealed …


Topical Administration Of Egf Suppresses Immune Response And Protects Skin Barrier In Dncb-Induced Atopic Dermatitis In Nc/Nga Mice, Young Je Kim, Mi Ji Choi, Dong Ho Bak, Byung Chul Lee, Eun Jung Ko, Ga Ram Ahn, Seung Won Ahn, Moo Joong Kim, Jungtae Na, Beom Joon Kim Aug 2018

Topical Administration Of Egf Suppresses Immune Response And Protects Skin Barrier In Dncb-Induced Atopic Dermatitis In Nc/Nga Mice, Young Je Kim, Mi Ji Choi, Dong Ho Bak, Byung Chul Lee, Eun Jung Ko, Ga Ram Ahn, Seung Won Ahn, Moo Joong Kim, Jungtae Na, Beom Joon Kim

Biological Sciences Faculty Publications

Atopic dermatitis (AD) is a common inflammatory skin disease characterized by a complex, heterogeneous pathogenesis including skin barrier dysfunction, immunology, and pruritus. Although epidermal growth factor (EGF) is essential for epithelial homeostasis and wound healing, the effect of EGF on AD remains to be explored. To develop a new therapy for AD, the anti-AD potential of EGF was investigated by inducing AD-like skin lesions in NC/Nga mice using 2,4-dinitrochlorobenzene (DNCB). EGF was administrated to NC/Nga mice to evaluate its therapeutic effect on DNCB-induced AD. EGF treatment improved dermatitis score, ear thickness, epidermal hyperplasia, serum total immunoglobulin E level, and transepidermal …


Sex-Based Differences In Anti-Predator Response Of Crickets To Chemical Cues Of A Mammalian Predator, Brian P. Tanis, Bradley Bott, Brian J. Gaston Jun 2018

Sex-Based Differences In Anti-Predator Response Of Crickets To Chemical Cues Of A Mammalian Predator, Brian P. Tanis, Bradley Bott, Brian J. Gaston

Biological Sciences Faculty Publications

Anti-predator behaviors like vigilance or hiding come at the expense of other fitness increasing behaviors such as foraging. To compensate for this trade-off, prey assess predation risk and modify the frequency of anti-predator behaviors according to the likelihood of the threat. In this study, we tested the ability of house crickets (Acheta domesticus) to indirectly assess predation risk via odors from a mammalian predator, Elliot's short-tailed shrew (Blarina hylophaga). As natural differences in encounter rates and predation risk differs between sexes, we tested if male and female crickets perceive similar rates of predation risk from the presence of shrew odor …


Bioinformatic Workflows For Generating Complete Plastid Genome Sequences—An Example From Cabomba (Cabombaceae) In The Context Of The Phylogenomic Analysis Of The Water-Lily Clade, Michael Gruenstaeudl, Nico Gerschler, Thomas Borsch Jan 2018

Bioinformatic Workflows For Generating Complete Plastid Genome Sequences—An Example From Cabomba (Cabombaceae) In The Context Of The Phylogenomic Analysis Of The Water-Lily Clade, Michael Gruenstaeudl, Nico Gerschler, Thomas Borsch

Biological Sciences Faculty Publications

The sequencing and comparison of plastid genomes are becoming a standard method in plant genomics, and many researchers are using this approach to infer plant phylogenetic relationships. Due to the widespread availability of next-generation sequencing, plastid genome sequences are being generated at breakneck pace. This trend towards massive sequencing of plastid genomes highlights the need for standardized bioinformatic workflows. In particular, documentation and dissemination of the details of genome assembly, annotation, alignment and phylogenetic tree inference are needed, as these processes are highly sensitive to the choice of software and the precise settings used. Here, we present the procedure and …