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The Effects Of Omega-3 Fatty Acids On Saccharomyces Cerevisiae Inositol Pathway Mutants, Daniel Antonio Colon Hidalgo, Marlene Murray-Nseula
The Effects Of Omega-3 Fatty Acids On Saccharomyces Cerevisiae Inositol Pathway Mutants, Daniel Antonio Colon Hidalgo, Marlene Murray-Nseula
Honors Theses
Bipolar disease is a severe and chronic debilitating mental disorder affecting 1-3% of the population. Omega-3-fatty acids have been shown to relieve symptoms of bipolar disorder and are not associated with the negative side effects of lithium and valproate, two of the commonly used drugs for treating this condition. The mechanism of action of omega-3-fatty acids remains unknown. Therefore the purpose of this study was to determine if, like lithium and valproate, omega-3-fatty acids affect inositol metabolism. This was accomplished by investigating the effect of the omega-3-fatty acid docosahexanoic acid (DHA) on the growth of inositol pathway mutants. To measure …