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Sorghum Distillers Dried Grain Lipid Extract Increases Cholesterol Excretion And Decreases Plasma And Liver Cholesterol Concentration In Hamsters, Jia Tse Hoi, Curtis L. Weller, Vicki Schlegel, Susan L. Cuppett, Ji-Young Lee, Timothy P. Carr
Sorghum Distillers Dried Grain Lipid Extract Increases Cholesterol Excretion And Decreases Plasma And Liver Cholesterol Concentration In Hamsters, Jia Tse Hoi, Curtis L. Weller, Vicki Schlegel, Susan L. Cuppett, Ji-Young Lee, Timothy P. Carr
Department of Biological Systems Engineering: Papers and Publications
Grain sorghum is a rich source of phytochemicals. In this study, male hamsters were fed AIN-93M diets supplemented with a hexane-extractable lipid fraction from sorghum distillers dried grains with solubles (DDGS). Diets contained 0.0%, 0.5%, 1.0%, and 5.0% (w/w) DDGS lipid extract. After 4 wk, the 5.0% DDGS lipids group had significantly lower plasma non-HDL cholesterol and liver esterified cholesterol concentration. Fecal neutral sterol (i.e., cholesterol) excretion was significantly higher in the 5.0% DDGS lipids group compared to the other treatments (66% higher compared to controls). Bile acid excretion was not affected by DDGS lipid intake. Fecal cholesterol excretion was …