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Bioinformatics

Semantic Provenance

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Role Of Semantic Web In Health Informatics, Satya S. Sahoo, Guo-Qiang Zhang, Amit P. Sheth Jan 2012

Role Of Semantic Web In Health Informatics, Satya S. Sahoo, Guo-Qiang Zhang, Amit P. Sheth

Kno.e.sis Publications

This tutorial weaves together three themes and the associated topics: [1] The role of biomedical ontologies [2] Key Semantic Web technologies with focus on Semantic provenance and integration [3] In-practice tools and real world use cases built to serve the needs of sleep medicine researchers, cardiologists involved in clinical practice, and work on vaccine development for human pathogens.


Janus: From Workflows To Semantic Provenance And Linked Open Data, Paolo Missier, Satya S. Sahoo, Jun Zhao, Carole Goble, Amit P. Sheth Jun 2010

Janus: From Workflows To Semantic Provenance And Linked Open Data, Paolo Missier, Satya S. Sahoo, Jun Zhao, Carole Goble, Amit P. Sheth

Kno.e.sis Publications

Data provenance graphs are form of metadata that can be used to establish a variety of properties of data products that undergo sequences of transformations, typically specified as workflows. Their usefulness for answering user provenance queries is limited, however, unless the graphs are enhanced with domain-specific annotations. In this paper we propose a model and architecture for semantic, domain-aware provenance, and demonstrate its usefulness in answering typical user queries. Furthermore, we discuss the additional benefits and the technical implications of publishing provenance graphs as a form of Linked Data. A prototype implementation of the model is available for data produced …


Semantic Provenance For Escience: Managing The Deluge Of Scientific Data, Satya S. Sahoo, Amit P. Sheth, Cory Andrew Henson Jan 2008

Semantic Provenance For Escience: Managing The Deluge Of Scientific Data, Satya S. Sahoo, Amit P. Sheth, Cory Andrew Henson

Kno.e.sis Publications

Provenance information in eScience is metadata that's critical to effectively manage the exponentially increasing volumes of scientific data from industrial-scale experiment protocols. Semantic provenance, based on domain-specific provenance ontologies, lets software applications unambiguously interpret data in the correct context. The semantic provenance framework for eScience data comprises expressive provenance information and domain-specific provenance ontologies and applies this information to data management. The authors' "two degrees of separation" approach advocates the creation of high-quality provenance information using specialized services. In contrast to workflow engines generating provenance information as a core functionality, the specialized provenance services are integrated into a scientific workflow …


Ontology Driven Semantic Provenance For Heterogeneous Bionomics Experimental Data, Satya S. Sahoo, Michael L. Raymer, Cory Andrew Henson, Amit P. Sheth, William S. York Jan 2008

Ontology Driven Semantic Provenance For Heterogeneous Bionomics Experimental Data, Satya S. Sahoo, Michael L. Raymer, Cory Andrew Henson, Amit P. Sheth, William S. York

Kno.e.sis Publications

Scientific experimental data generated by all the bionomic technologies is characterized by heterogeneity in its representation formats, constituents, and generation processes and, therefore, also in its usage. Using the proteomics domain we demonstrate the important role of provenance information o manage, interpret and analyze experimental data. We present a novel approach that employs an ontology as a knowledge model to automatically create semantic provenance information for high-throughput mass spectrometry (MS) data in the glycoproteomics domain. The Semantic Provenance Annotation of Data in protEomics (SPADE) implementation is based on the ProPreO ontology, a large-process ontology ( ~500 classes, 40 named relationships …