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Molecular Biodiversity Of Foraminifera, Rabindra Thakur
Molecular Biodiversity Of Foraminifera, Rabindra Thakur
Masters Theses
Foraminifera are a diverse clade of mostly shell-building single-celled organisms. Estimation of foraminiferal diversity is critical for understanding past and present climatic conditions, as they are highly sensitive to environmental perturbations. Biodiversity estimates of foraminifera began with the counting of test (i.e., shell) microfossils composed of calcium carbonate, as they are well preserved in sediment samples. However, this view has changed with molecular biodiversity estimates, which suggest that early-diverging single-chamber (i.e., "monothalamid") species that lack preservation ability are more diverse than anticipated. Although biodiversity estimates of foraminifera at the molecular level have changed our perceptions, they possess various challenges, especially …
Evaluation Of Mesenchymal Stem Cells In Autoimmune Disease: A Systematic Review And Meta-Analysis, Hailey Nicole Swain
Evaluation Of Mesenchymal Stem Cells In Autoimmune Disease: A Systematic Review And Meta-Analysis, Hailey Nicole Swain
Masters Theses
"Mesenchymal stem cells, also known as multipotential stem/progenitor cells and mesenchymal stem/progenitor cells, are denoted by the acronym MSCs. MSCs can differentiate into multiple lineages from different germ layers in vitro, and in limited situations, in vivo. MSCs have broad anti-inflammatory and immune-modulatory properties, which is the greatest focus of MSCs in clinical testing. Despite their promise and use in over 950 clinical trials, pivotal questions remain unanswered. Recent clinical trials have demonstrated that when MSCs are harvested from autoimmune patients, they show a reduction in their therapeutic efficacy in comparison to MSCs from a healthy person. Identifying quality MSCs …