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The Proteogenomic Mapping Tool, William S. Sanders, Nan Wang, Susan M. Bridges, Brandon M. Malone, Yoginder S. Dandass, Fiona M. Mccarthy, Bindu Nanduri, Mark L. Lawrence, Shane C. Burgess
The Proteogenomic Mapping Tool, William S. Sanders, Nan Wang, Susan M. Bridges, Brandon M. Malone, Yoginder S. Dandass, Fiona M. Mccarthy, Bindu Nanduri, Mark L. Lawrence, Shane C. Burgess
Faculty Publications
Background: High-throughput mass spectrometry (MS) proteomics data is increasingly being used to complement traditional structural genome annotation methods. To keep pace with the high speed of experimental data generation and to aid in structural genome annotation, experimentally observed peptides need to be mapped back to their source genome location quickly and exactly. Previously, the tools to do this have been limited to custom scripts designed by individual research groups to analyze their own data, are generally not widely available, and do not scale well with large eukaryotic genomes.
Results: The Proteogenomic Mapping Tool includes a Java implementation of …