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Bioethics and Medical Ethics

Thomas Jefferson University

2006

Survival rate

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Increasing Illness Severity In Very Low Birth Weight Infants Over A 9-Year Period, David A. Paul, Kathleen H. Leef, Robert G. Locke, Louis Bartoshesky, Judy Walrath, John L. Stefano Feb 2006

Increasing Illness Severity In Very Low Birth Weight Infants Over A 9-Year Period, David A. Paul, Kathleen H. Leef, Robert G. Locke, Louis Bartoshesky, Judy Walrath, John L. Stefano

Department of Pediatrics Faculty Papers

Background: Recent reports have documented a leveling-off of survival rates in preterm infants through the 1990's. The objective of this study was to determine temporal changes in illness severity in very low birth weight (VLBW) infants in relationship to the outcomes of death and/or severe IVH.

Methods: Cohort study of 1414 VLBW infants cared for in a single level III neonatal intensive care unit in Delaware from 1993-2002. Infants were divided into consecutive 3-year cohorts. Illness severity was measured by two objective methods: the Score for Neonatal Acute Physiology (SNAP), based on data from the 1st day of …