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Analysis Of Events Governing The Meiotic Division In Mouse Spermatocytes, Shannon Stewart Eaker

Doctoral Dissertations

The meiotic division is essential for successful gametogenesis. However, many events occurring during male and female meiotic development remain poorly understood. While it is known that chromosomes must pair, recombine, and segregate to form gametes, critical questions remain. How and when do these events occur with respect to each other? What mechanisms monitor their developmental success? Insight into these questions is provided in this dissertation, using the mouse spermatocyte as a model. The purpose of this work is to aid in the overall understanding of mammalian meiosis.

After an introduction into mammalian meiosis in Part I, a temporal order of …