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The Spinning Thread, Halley Marie Cotton Jan 2016

The Spinning Thread, Halley Marie Cotton

All ETDs from UAB

The poems comprised within this collection reimagine the Southern culture and identity. As a whole these poems explore themes such as family, craftsmanship, folklore, and the tension between humanity and nature. The overarching narrative revolves around the idea of transformation. Here, the speaker transforms from the mundane to the mythological and natural elements are acted upon to produce a shift in their physical state. These poems examine several inter- and intra- personal relationships typically in a state of recollection or unrest. Memory and a harkening to ancestral roots tend to inform the speaker’s thoughts and actions. While many of these …


Emotion Socialization And Emotional Functioning In Late Adolescence And Emerging Adulthood, Jinhong Guo Jan 2016

Emotion Socialization And Emotional Functioning In Late Adolescence And Emerging Adulthood, Jinhong Guo

All ETDs from UAB

Parental emotion socialization has been associated with youth emotional development. However, less is known about the influences of emotion socialization on emotional functioning in late adolescence and emerging adulthood. The first manuscript examined the factor structure of The Emotions as a Child Scale (EAC) in late adolescence and emerging adulthood and evaluates its measurement invariance across gender and ethnicity. The results showed that parental responses to children’s negative emotions could be categorized into supportive and unsupportive responses and the EAC demonstrated stronger measurement invariance across gender than ethnic groups. The second manuscript examined coping strategies as mediators of the relationship …


Machine Learning Of Composite Concepts And The Alleviation Of The Content Completeness Problem In Text Mention Normalization, John David Osborne Jan 2016

Machine Learning Of Composite Concepts And The Alleviation Of The Content Completeness Problem In Text Mention Normalization, John David Osborne

All ETDs from UAB

A critical area in the field of information extraction is the assignment of ontological categories (meaning) to fragments of natural language. These fragments are termed ``utterances'' when referring to a continuous fragment or ``mentions'' when the fragment may be discontinuous. In text, most approaches to ontological assignment use named entity recognition (NER) to first discover mention boundaries. This can then be followed by a concept recognition or normalization process to assign a more precise conceptual category to the NER discovered mention. Typically this semantic assignment is represented by only a single identifier from an ontology. If the provided semantic categories …


Plasma Enhanced Chemical Vapor Deposition Of Metal-Boride Interfacial Layers As Diffusion Barriers For Nanostructured Diamond Growth On Cobalt Containing Alloys Cocrmo And Wc-Co, Jamin Michael Johnston Jan 2016

Plasma Enhanced Chemical Vapor Deposition Of Metal-Boride Interfacial Layers As Diffusion Barriers For Nanostructured Diamond Growth On Cobalt Containing Alloys Cocrmo And Wc-Co, Jamin Michael Johnston

All ETDs from UAB

This work is a compilation of theory, finite element modeling and experimental research related to the use of microwave plasma enhanced chemical vapor deposition (MPECVD) of diborane to create metal-boride surface coatings on CoCrMo and WC-Co, including the subsequent growth of nanostructured diamond (NSD). Motivation for this research stems from the need for wear resistant coatings on industrial materials, which require improved wear resistance and product lifetime to remain competitive and satisfy growing demand. Nanostructured diamond coatings are a promising solution to material wear but cannot be directly applied to cobalt containing substrates due to graphite nucleation. Unfortunately, conventional pre-treatment …


Race Effects Of Perceived Weight Status And Its Relationship With Unmet Health Care Need, Sarah B. Rutland Jan 2016

Race Effects Of Perceived Weight Status And Its Relationship With Unmet Health Care Need, Sarah B. Rutland

All ETDs from UAB

This study (n=9,630) evaluates the influence of race on the relationship between perceived weight status (PWS) and obtaining health care when a respondent thought care was needed (unmet need) among young adults (age 24-34) using Wave IV of the National Longitudinal Study of Adolescent to Adult Health. Using the framework of fundamental cause, I assume that health disparities between groups is due to unequal distribution of resources between those groups that enables a group with more resources, such as wealth or race privilege, to access and support better health outcomes. I focus on race, and specifically racism, as a resource …


Liminal, Cheyenne Day Taylor Jan 2016

Liminal, Cheyenne Day Taylor

All ETDs from UAB

The following thesis is a creative one, composed of thirty poems written in various forms. Included in this work are different types of sonnets, including Elizabethan and Petrarchan, experiments with less frequented forms such as villanelle, pantoum, and triolet, and many poems written in blank verse and syllabics. Thematically, this collection deals with liminality—times of transition and uncertainty where people are no longer exactly who or what they used to be but are not quite fully across the threshold into a new phase. This liminality presents in multiple different ways, with speakers who are dealing with transitions such as ending …


Investigating The Mechanisms Of Dopaminergic Signaling In Regulating Refractive Error, Alexander Hadwyn Ward Jan 2016

Investigating The Mechanisms Of Dopaminergic Signaling In Regulating Refractive Error, Alexander Hadwyn Ward

All ETDs from UAB

Myopia is a significant public health problem. Most juvenile-onset myopia occurs because the eye becomes too long for its own optics. We study mechanisms regulating refractive error in an animal model, the tree shrew (Tupaia glis belangeri), a mammal closely related to primates. We use translucent diffusers to induce form deprivation myo-pia (FDM). A role of the retinal dopaminergic system has been validated during the de-velopment of FDM. In this study, in Specific Aim 1, we used intravitreal injections as a way to deliver sub-stances to the retina to investigate their effect on eye growth and induced myopia. However, a …


Neural Network Associated With The Psychobiological Response To Stress, Muriah Wheelock Jan 2016

Neural Network Associated With The Psychobiological Response To Stress, Muriah Wheelock

All ETDs from UAB

The biobehavioral response to acute stress is an allostatic process. Dysregulation of the stress response has been implicated in allostatic load and the pathophysiology of a wide range of physical and psychological disorders. There have been considerable advances within the last two decades in the field’s understanding of allostatic load and a consistent finding across studies has been that individual differences are the norm rather than the exception. That is, exposure to stress seems to have minimal negative consequences for some, but substantial negative consequences for others. Determining the neural processes associated with individual differences in stress reactivity may advance …


Temporal Co-Expression Network Construction, Leading Sub-Network Identification, And Time Point Alignment In The Integration Of Phase Transition Theory And Systems Biology And The Application To Human Type 1 Diabetes, Nathaniel Wolanyk Jan 2016

Temporal Co-Expression Network Construction, Leading Sub-Network Identification, And Time Point Alignment In The Integration Of Phase Transition Theory And Systems Biology And The Application To Human Type 1 Diabetes, Nathaniel Wolanyk

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Systems biology is a rapidly expanding field used to tackle a wide range of biological problems. Systems biology arose to explain areas that detailed biological analysis, such as genetics and biopsies, struggled with. Systems biology is the study of the complexity within a biological system of multiple units that is due to the interaction among the units. In this dissertation systems biology will be combined with phase transition theory from physics to create a new analysis method for complex diseases and apply this new method to a longitudinal dataset on Type 1 Diabetes (T1D) to identify the key contributing molecules …


"Sleep Tight, Don't Let The Dysfunction Bite!" The Relationship Between Sleep Problems And Behavioral And Emotional Problems In Adolescence, Meredith Ashley Henry Jan 2016

"Sleep Tight, Don't Let The Dysfunction Bite!" The Relationship Between Sleep Problems And Behavioral And Emotional Problems In Adolescence, Meredith Ashley Henry

All ETDs from UAB

The effects of sleep on behavioral and emotional functioning in a low income, urban sample of 84 African American adolescents was investigated over 3 years (mean ages: 13.36, 14.76, and 16.14 years) of parent and child interviews. Results suggest child-reported sleep duration decreased while all other sleep variables remained stable. Substance use increased over time. Physical aggression and conduct problems decreased; depression, emotional problems, and hyperactivity/inattention remained stable until late adolescence and then decreased. Lower duration of sleep and more sleep problems at age 13 predicted more conduct problems at age 15 which, in turn, predicted less sleep duration and …


Study Of Cobalt, Cobalt-Iron, And Chromium Doped Ii-Vi Media For Laser Applications, Jeremy M. Peppers Jan 2016

Study Of Cobalt, Cobalt-Iron, And Chromium Doped Ii-Vi Media For Laser Applications, Jeremy M. Peppers

All ETDs from UAB

The middle infrared (mid-IR) spectral range of 2-15 μm possesses characteristics that make it interesting for a number of applications such as spectroscopy, free-space communication, remote detection of organic compounds, materials processing and medical diagnosis. Many organic molecules exhibit strong absorption in this spectral range, rendering their detection and identification possible. There also exist bands of atmospheric transmission which can allow free-space propagation of mid-IR light over considerable distances within the atmosphere. Because of these, there is an increasing demand for broadly tunable laser sources operating in this spectral range. II-VI wide bandgap semiconductor hosts doped with transition metal (TM) …


Targeting Voltage Gated Sodium Channels For Prevention Of Breast Cancer Metastasis, Shilpa Dutta Jan 2016

Targeting Voltage Gated Sodium Channels For Prevention Of Breast Cancer Metastasis, Shilpa Dutta

All ETDs from UAB

Voltage gated sodium channels (VGSC) are a recently identified drug target involved in the breast cancer invasion mechanism. VGSCs participate in the acidification of the perimembrane, activating the cysteine proteases, cathepsin B and S, thereby triggering the proteolysis of the extracellular matrix and the basement membrane, thereby promoting cell invasion. Highly aggressive, invasive breast cancer cells dramatically overexpress one subtype of VGSC, nNav1.5. Described here are the design, synthesis and in vitro evaluation of drug-like, small molecule blockers of nNav1.5 that are potential therapeutic agents for the prevention of breast cancer metastasis. Initially, five compounds were designed and synthesized based …


Liberty And Collaboration For All: A Case Study On Collective Impact, Social Capital, And Community Inclusion, Laura Peyton Vickery Jan 2016

Liberty And Collaboration For All: A Case Study On Collective Impact, Social Capital, And Community Inclusion, Laura Peyton Vickery

All ETDs from UAB

Disenfranchised communities often face exclusion at the hands of outside organizations trying to assist. Citizens within the community are excluded and left with few means of actively participating in the conversation and development surrounding these communities. This paper takes the position that the imbalance of power dynamics, where citizens become subjects, does not fully utilize the potential of those inside and those from outside the community. As discussed in Chapter 1, utilizing social capital to build networks and integrate insider and outsider organizations and resources will ultimately create optimization. Chapter 2 uncovers historical examples of civic life and a new …


Boundary Construction And Identity Maintenance In Institutionalized Versus Non-Institutionalized Women Methamphetamine Users, Megan Elisabeth Webb Jan 2016

Boundary Construction And Identity Maintenance In Institutionalized Versus Non-Institutionalized Women Methamphetamine Users, Megan Elisabeth Webb

All ETDs from UAB

Since the late 1990s there has been an increase in the use of methamphetamine (meth) across the United States. Concerns about the physical, mental, and societal effects of the drug have been fueled by the media and anti-drug campaigns and have contributed to the demonization of meth and its users. People who use meth construct symbolic boundaries in an attempt to navigate the stigma associated with their drug use and in an attempt to maintain a positive self-identity. Symbolic boundaries are the distinctions, or social categories, that individuals make in attempt to categorize certain people and behaviors. One way that …


An Investigation Into The Developmental Response Of The Amphipod Hyalella Azteca To Different Predator-Related Chemical Cues, William Ryan James Jan 2016

An Investigation Into The Developmental Response Of The Amphipod Hyalella Azteca To Different Predator-Related Chemical Cues, William Ryan James

All ETDs from UAB

Predator chemical cues have been widely demonstrated to influence developmental plasticity in aquatic prey. However, understanding the role that conspecifics have on an individual’s anti-predator response has received little attention. The present thesis investigated the developmental plasticity of individual and groups of the amphipod Hyalella azteca chronically exposed to kairomones from predatory sunfish. Previous field studies have suggested that small body size in H. azteca is a likely adaptive response to reducing predation by sunfish, but no experimental studies have been carried out to test if the amphipods have a developmental response to the presence of sunfish. Containers with single …


A Comprehensive Investigation Of Hp1b, A Chromatin Protein, And Its Role In Aging, Benjamin Mills Mills Jan 2016

A Comprehensive Investigation Of Hp1b, A Chromatin Protein, And Its Role In Aging, Benjamin Mills Mills

All ETDs from UAB

Genetic regulation determines which genes are expressed, in which tissues, at which time, and to which level. This regulation is necessary for proper organismal development, and loss of gene regulation can result in phenotypic consequences. As organisms grow older, gene regulation often begins to fail, resulting in negative phenotypic outcomes associated with aging. The exact reason for this failure of gene regulation remains unknown, but current models suggest that chromatin, and its associated proteins, plays a large role. The structure of chromatin impacts gene expression, directly affecting several phenotypes including aging. In this study, we investigate HP1B, a chromatin protein, …


Studies In New Materials For Intermediate Temperature Solid Oxide Fuel Cells, Alex Skinner Jan 2016

Studies In New Materials For Intermediate Temperature Solid Oxide Fuel Cells, Alex Skinner

All ETDs from UAB

Ceramic materials have historically been of interest for their thermal and mechanical properties. However, certain ceramic materials can have very interesting electrical, magnetic and optical properties, leading to a new subclass, the electroceramics. Perovskites, in particular, have become the subject of intense research in this field. Specifically, doped barium zirconates have shown high proton conductivity in the intermediate temperature range (600 – 800°C), making them advantageous for use in solid oxide fuel cells. Solid oxide fuel cells (SOFCs) are electrochemical devices that convert chemical energy into electricity using ion-conducting oxide ceramics as electrolytes. The anode component of the cell is …


Natural Variation Of The Ire1a Gene Of Arabidopsis Thaliana And Its Effects On Abiotic Stress Tolerance, Brenna Cathryn Terry Jan 2016

Natural Variation Of The Ire1a Gene Of Arabidopsis Thaliana And Its Effects On Abiotic Stress Tolerance, Brenna Cathryn Terry

All ETDs from UAB

The IRE1a protein is a key player in the response of plant cells to endoplasmic reticulum (ER) stress by activating bZIP60, a transcription factor implicated in effective ER stress response. Natural variation has been observed in the expression of the IRE1a gene in natural accessions of Arabidopsis thaliana, a model plant organism. Here, an attempt is made to correlate basal natural variation of IRE1a with response of the plant to abiotic stress. Abiotic stress response through IRE1a activity, specifically bZIP60 transcript splicing, does correspond to basal IRE1a expression. Additionally, alleles of the IRE1a gene were determined to exist as a …


Meta-Analysis Of Cognitive Performance In Fibromyalgia, Tyler Reed Bell Jan 2016

Meta-Analysis Of Cognitive Performance In Fibromyalgia, Tyler Reed Bell

All ETDs from UAB

Fibromyalgia is a disease that encompasses difficulties with pain, physical function, and emotion, but is also characterized by complaints of poor cognition. Over the last two decades, a vast amount of literature has tested for cognitive differences between individuals with and without fibromyalgia. The purpose of the current study was to conduct a quantitative synthesis on these differences across multiple cognitive domains. After a systematic search of eligible studies, random-effect meta-analyses were conducted on effect sizes (Hedges’ g) derived from 37 cross-sectional studies covering domains of processing speed, memory and executive function. Participants included persons with fibromyalgia (total n = …


Latin American Immigration To The Deep South: Community Responses In Birmingham Metro Area, Al (1995-2010), Nadejda Bontcheva-Loyaga Jan 2016

Latin American Immigration To The Deep South: Community Responses In Birmingham Metro Area, Al (1995-2010), Nadejda Bontcheva-Loyaga

All ETDs from UAB

Starting in the late 1990s, Latin American immigrants began settling in great numbers in non-traditional immigration states in the Deep South. Birmingham, Alabama, one of the large cities in the region, rapidly experienced a staggering growth in its Latin American immigrant population, which created numerous difficulties with access to services and intercommunity relations. The current study looks at these difficulties and the institutional framework that was established to address them and support the settlement process of incoming immigrants in the city. The study analyses the most pressing issues that needed to be addressed in five areas – healthcare, language and …


Sea Urchins Under Predicted Near-Future Ocean Conditions: The Effects Of Ocean Warming And Acidification On Physiology And Behavior, Cecilia Joy Brothers Jan 2016

Sea Urchins Under Predicted Near-Future Ocean Conditions: The Effects Of Ocean Warming And Acidification On Physiology And Behavior, Cecilia Joy Brothers

All ETDs from UAB

Sea urchins (Class Echinoidea) play important economic and ecological roles in the marine ecosystems they inhabit. However, climate change is causing seawater temperatures to increase and pH and the saturation state of polymorphs of calcium calcite to decrease at unprecedented rates, and these changes may have serious implications for the fitness and survival of sea urchin populations. The purpose of the present dissertation was to determine the effects of ocean warming and acidification on the physiology and behavior of sea urchins. This research was conducted on three sea urchin taxa (Lytechinus variegatus, Heliocidaris erythrogramma, and Sterechinus spp.) representing species that …


Mending Rural America: Disaster Recovery In Small Municipalities, Marybrook Burchfield Jan 2016

Mending Rural America: Disaster Recovery In Small Municipalities, Marybrook Burchfield

All ETDs from UAB

Long-term disaster recovery is an important aspect of public administration, especially as the United States is more frequently affected by natural disasters. Federal, state and local governments must adapt and respond to their citizens’ needs. This research analyzes one small Alabama community’s recovery following a devastating series of tornados. This case study on the City of Cordova is conducted via a document analysis of local newspaper articles, government documents and personal communication. The experiences of Cordova are analyzed using principles outlined in FEMA’s National Disaster Recovery Framework. The analysis suggests that disaster recovery in a small city or town is …


Primary Visual Cortex And Plasticity Following Central Vision Loss, Wesley K. Burge Jan 2016

Primary Visual Cortex And Plasticity Following Central Vision Loss, Wesley K. Burge

All ETDs from UAB

Age-related macular degeneration is one of the most common causes of blindness in the industrialized world, and the advanced phase of the disease that causes significant vision impairment affects nearly 2 million individuals in the United States (Friedman et al., 2004). It is characterized by the degeneration and eventual death of retinal photoreceptors in the macula, which is the area of the retina that mediates central vision. The resulting loss of cells often leads to profound deficits in visual function. However, many individuals with age-related macular degeneration learn to use their spared peripheral vision for visual tasks such as reading, …


Symbols Of Independence, Love, And Sorrow: Georgia O'Keeffe's Skyscraper Series, Kelly Allen Gentry Jan 2016

Symbols Of Independence, Love, And Sorrow: Georgia O'Keeffe's Skyscraper Series, Kelly Allen Gentry

All ETDs from UAB

Georgia O’Keeffe (1887-1986) became known as one of the first and most prolific American modern artists of the twentieth century. Her expansive oeuvre, which spans over six decades, is primarily comprised of pure abstractions, large-scale flower paintings, and series of landscapes, crosses, and bones from the southwestern landscape of New Mexico, where she spent the latter half of her life. In the mid-1920s however, O’Keeffe created approximately twenty images of the skyscrapers of New York City, her home from 1918 to 1949. This thesis argues that within this skyscraper series, O’Keeffe fully realized her uniquely personal and recognizable language. This …


The (Non)Tragic Passing Of Rena Walden: Black Female Agency In Charles Chesnutt's The House Behind The Cedars, Sarah Emily Goggans Jan 2016

The (Non)Tragic Passing Of Rena Walden: Black Female Agency In Charles Chesnutt's The House Behind The Cedars, Sarah Emily Goggans

All ETDs from UAB

This project analyzes Charles W. Chesnutt’s The House Behind the Cedars in an attempt to accredit Chesnutt as a forerunner of Critical Race Theory (CRT). Secondly, this project argues that Rena gains agency solely through her black ancestry in her ability to read and write both cultural and written texts. I will also argue in that creating a metanarrative form for his novel, Chesnutt is able to provide a radically feminist text through his representation of the power of Rena’s literacy, and furthermore, that Chesnutt is able to critique the laws and customs of normative white society. Lastly, this project …


Toward A Scalable, Transactional, Fault-Tolerant Message Passing Interface For Petascale And Exascale Machines, Amin Hassani Jan 2016

Toward A Scalable, Transactional, Fault-Tolerant Message Passing Interface For Petascale And Exascale Machines, Amin Hassani

All ETDs from UAB

Increases in the scale of computing machines directly correlate with the rate of failures. High Performance Computing (HPC) applications provide fault-tolerance through redundancy in “resources.” However, dominant underlying parallel programming models, such as Message Passing Interface (MPI), are sensitive to the slightest errors such that a node failure aborts the entire application stack. Recent advances in application level fault-tolerance require a fault-tolerant MPI implementation. Studies (including this one) investigate all previous approaches thoroughly and determined their limitations. The purpose of this dissertation is to design a fault-tolerant MPI for data-parallel and Bulk Synchronous Parallel (BSP) applications by increasing the probability …


Andy Loves Richard: The Revelations Of Vote Mcgovern (1972), Amelia Hobson Jan 2016

Andy Loves Richard: The Revelations Of Vote Mcgovern (1972), Amelia Hobson

All ETDs from UAB

In 1972, Pop artist Andy Warhol was asked by the Democratic National Convention to design a poster for the campaign of George McGovern in his race against presidential incumbent Richard Nixon. The final print was produced in an edition of 250 prints and sold at auction with the proceeds donated to McGovern’s campaign. The work commands almost immediate attention as it depicts not George McGovern, as might be expected, but his opponent President Richard Nixon. Nixon’s head consumes the greater portion of the print and looms over the scrawled text, “VOTE MCGOVERN.” Nixon’s eyes are yellow and his face green …


Resveratrol And Pterostilbene: A Novel Combinatorial Epigenetic Therapy In Targeting Triple-Negative Breast Cancer, Rishabh Kala Jan 2016

Resveratrol And Pterostilbene: A Novel Combinatorial Epigenetic Therapy In Targeting Triple-Negative Breast Cancer, Rishabh Kala

All ETDs from UAB

Although the majority of breast cancers are estrogen receptor (ER)-positive, progesterone receptor (PGR)-positive and/or HER2 positive, approximately 20% of them are triple-negative and lack ER, PGR and HER2 protein expression. These cancers are robust and hard to treat with conventional hormone therapies. The plant-based dietary compounds resveratrol and pterostilbene (a dimethyl derivative of resveratrol) have been shown to modulate the growth of cancer cells individually via affecting genetic and epigenetic profiles, but none of the studies to date have addressed the effects of these two compounds in combination in targeting triple-negative breast cancers (TNBC). We have discovered a synergistic effect …


Fastnumerics: Compiling Matlab To C++, Sujan Khadka Jan 2016

Fastnumerics: Compiling Matlab To C++, Sujan Khadka

All ETDs from UAB

Matlab is a popular language among researchers and scientists. It allows mathematical and scientific calculations to be formulated in a way that is close to mathematical notation which makes developing prototypes easier and faster. Our preliminary results show that computation intensive programs written in Matlab tend to be slower than equivalent programs written in C++. C++ being a compiled language exposes advanced optimization opportunities that will help speed up sequential code as compared to Matlab. Hence, there is a need to translate Matlab code to languages like C/C++ for maximum performance. C++ also provides libraries to run a program in …


Towards Trustworthy Authentication In Service Oriented Computing, Rasib Hassan Khan Jan 2016

Towards Trustworthy Authentication In Service Oriented Computing, Rasib Hassan Khan

All ETDs from UAB

Today's Internet and network-based applications are highly driven by the service-oriented architecture model. Given the variety of online services, we hypothesized that there is a significant non-uniformity in the behavior of users pertaining to security-oriented practices on the Internet. We performed statistical analysis on open source user-survey datasets to establish the validity of the statement. We performed further study with respect to the security-oriented behavioral practices in developing countries. We were able to determine certain traits and insecure practices that general Internet users from both developed and developing countries adopt, and addressed the corresponding issues to devise secure authentication technologies …