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Suicide Ideation And Risk Factors Among Correctional Officers, Logan Lavender Jan 2023

Suicide Ideation And Risk Factors Among Correctional Officers, Logan Lavender

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The correctional work environment is detrimental to correctional officers’ (COs) health and wellness. While research shows that COs experience high rates of stress, PTSD, and other mental and physical health problems, relatively little research has examined the issue of CO suicide. The current study addresses this knowledge gap by drawing on a survey of COs from Washington state (N=420). Utilizing a Structural Equation Modeling (SEM) framework, this study examines the prevalence of critical incidents (CIs), work stress, PTSD, and suicide ideation, estimates the degree to which exposure to CIs predicts suicide ideation, and assesses how work stress and PTSD moderate …


Examining The Pathophysiology Through Which Violence Exposure Varies With Functional Brain Connectivity And The Psychophysiological Response To Stress, Heather Elizabeth Dark Jan 2021

Examining The Pathophysiology Through Which Violence Exposure Varies With Functional Brain Connectivity And The Psychophysiological Response To Stress, Heather Elizabeth Dark

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Violence exposure during childhood and adolescence is associated with susceptibility to internalizing disorders such as depression and anxiety. The relationship between childhood violence exposure and internalizing disorders may be explained by changes in brain function. For example, childhood maltreatment, including violence exposure, is associated with changes in brain regions that are important for emotion regulation. Reciprocal connections among these brain regions are important for healthy responses to stress. Thus, examining how childhood violence exposure varies with acute stress-induced changes in functional brain connectivity and psychophysiological stress responses may elucidate how childhood violence exposure may contribute to susceptibility to internalizing disorders. …


Stress, Inflammation, And Mood: A Role For Leptin?, Kathleen Hodgin Jan 2021

Stress, Inflammation, And Mood: A Role For Leptin?, Kathleen Hodgin

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Prior research has suggested a possible role for the proinflammatory adipokine leptin in depression. Leptin has also been associated with stress, a known predictor of depression. The purpose of this project was to investigate associations between stress, leptin, and depressed mood. We used data from a larger observational study that collected daily levels of plasma leptin and self-reported stress and depressed mood from 55 women over 25 days. Women with and without chronic fatigue syndrome (CFS) were included. We hypothesized the following: increased stress would be associated with both worsened mood and higher leptin, and that leptin would be positively …


A Stress Process Approach To Assessing Caregiver Burden, Depressive Symptoms, And Quality Of Life: The Role Of Attachment In Adult Relationships, Ghislaine Celine Atkins Jan 2021

A Stress Process Approach To Assessing Caregiver Burden, Depressive Symptoms, And Quality Of Life: The Role Of Attachment In Adult Relationships, Ghislaine Celine Atkins

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Aging adults (65 years and older) are projected to be the largest age group in the United States by around the year 2030. Importantly, the population of aging adults is expected to outnumber their adult children for the first time by the year 2033. The extant literature posits that the majority of carer-care-recipient relationships are between adult children/in law and their aging parent or a spouse/partner. Familial carers dealing with these multiple stressors are more likely to exhibit depressive symptoms, have higher appraisals of stress and have worse quality of life. This dissertation project utilized sociologist Pearlin’s Stress Process Model …


Examining The Role Of The Unfolded Protein Response In Depression, Matthew Timberlake Jan 2019

Examining The Role Of The Unfolded Protein Response In Depression, Matthew Timberlake

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Depression is the leading cause of disability worldwide and impacts nearly 350 million people with a disproportionate representation in women with a 1:1.7 ratio of occurrence compared to men. This disorder is characterized by shifts in mood to include feelings of hopelessness, sadness, and lethargy as well as changes in diet, motivation, and sleep patterns. Further, over 50% of patients who struggle with depression also have suicidal ideation and as many as 10% of those commit suicide. At present, treatment plans include behavioral therapy (often) in conjunction with antidepressant medications which act on monoamines and their circuits in the central …


Effect Of Occupational Demands On Driving Safety In Surgical Residents, Benjamin Mcmanus Jan 2018

Effect Of Occupational Demands On Driving Safety In Surgical Residents, Benjamin Mcmanus

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The Accreditation Council for Graduate Medical Examination recently revised and implemented duty hour standards that increased maximum duty hours for first year medical residents and reduced the minimal amount of time off between duty periods for all medical residents. The new standards were introduced largely without consideration of empirical research on objectively measured occupational health and safety factors for medical residents, particularly in contexts where their safety may be at-risk such as driving. Little work has examined driving performance in medical residents at multiple periods surrounding duty, including in reference to off-duty driving performance as a baseline. Certain work-related factors …


Neural Network Associated With The Psychobiological Response To Stress, Muriah Wheelock Jan 2016

Neural Network Associated With The Psychobiological Response To Stress, Muriah Wheelock

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The biobehavioral response to acute stress is an allostatic process. Dysregulation of the stress response has been implicated in allostatic load and the pathophysiology of a wide range of physical and psychological disorders. There have been considerable advances within the last two decades in the field’s understanding of allostatic load and a consistent finding across studies has been that individual differences are the norm rather than the exception. That is, exposure to stress seems to have minimal negative consequences for some, but substantial negative consequences for others. Determining the neural processes associated with individual differences in stress reactivity may advance …


The Role Of Spinal Serotonergic Receptors 5-Ht1a And 5-Ht3 In Stress-Induced Urinary Bladder Hypersensitivity, Chelsea L. Crawford Jan 2014

The Role Of Spinal Serotonergic Receptors 5-Ht1a And 5-Ht3 In Stress-Induced Urinary Bladder Hypersensitivity, Chelsea L. Crawford

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Disorders in which pain originates from the urinary bladder such as interstitial cystitis (IC) are steadily increasing in prevalence. A common finding among patients with IC is the comorbidity with stress or anxiety disorders. In rats, footshock stress alone is sufficient to elicit bladder hypersensitivity. Serotonin (5-hydroxytryptamine; 5-HT) has been established as a mediator in anxiety and pain separately, but little is known about the role of 5-HT in stress-induced visceral hypersensitivity. The current set of studies addresses three main concerns: (1) the impact of spinal 5-HT1A and 5-HT3 receptor blockade with WAY-100635 (10 µg) and ondansetron (10 µg), respectively, …


Stress And Myostatin In Salmoninae, Nicholas Galt Jan 2014

Stress And Myostatin In Salmoninae, Nicholas Galt

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The relationship between the muscle growth inhibitor, myostatin, and the stress response has been extensively studied in mammals, and myostatin is now known to partially mediate the degradative effects of stress in skeletal muscle. In fish, this relationship has not yet been clearly described. Herein, the effects of two stress mimetics, cortisol treatment and crowding, on myostatin-1a, -1b, and -2a expression in rainbow trout (Oncorhynchus mykiss), cutthroat trout (Oncorhynchus clarki), Chinook salmon (Oncorhynchus tshawytscha), brook trout (Salvelinus fontinalis), and Atlantic salmon (Salmo salar) are described. In study I, no clear effects on myostatin mRNA expression were detected in rainbow trout …


Estrogen Increases Stress Resilience And Hippocampal Synaptic Physiology In The Learned Helplessness Model Of Depression In Female Rats, Teruko Michelle Bredemann Jan 2011

Estrogen Increases Stress Resilience And Hippocampal Synaptic Physiology In The Learned Helplessness Model Of Depression In Female Rats, Teruko Michelle Bredemann

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A recent focus of psychiatric research is estrogen related mood disorders such as postpartum depression and major depressive disorder in women. It is now clear that women are more susceptible to depression in response to stress during reproductive events when ovarian hormones are low or fluctuating. Depressive episodes are characterized by feelings of helplessness and despair as well as learning and memory impairments that have been linked to the hippocampus. Thus, decreased functioning of hippocampal circuits likely contributes to the cognitive symptoms associated with depression. Preclinical research shows that stress, which triggers depressive episodes, decreases the ability of excitatory synapses …


The Effect Of The Release Of A Thermal Stressor On Bluegill (Lepomis Macrochirus) Morphology And Physiology, Jessica Eagar Jan 2011

The Effect Of The Release Of A Thermal Stressor On Bluegill (Lepomis Macrochirus) Morphology And Physiology, Jessica Eagar

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Temperature is considered a very important abiotic factor in fish communities. An increase in water temperature, as is found with the use of nuclear production reactors, can act as a stressor in aquatic systems. The P-reactor, operational from 1954-1988, on the Savannah River Site near Aiken, South Carolina, utilized the Par Pond Reservoir System as part of its cooling mechanisms. During reactor operation, heated effluents were displaced into Pond C, causing the water to be heated to around 45° C. Fischer (1994) found that the bluegill population had adapted with changes to their morphology and physiology. The bluegill from the …


The Impact Of Stressful Neighborhoods On The Mental Health Of Emerging Adolescents, Vicki P. Winstead Jan 2011

The Impact Of Stressful Neighborhoods On The Mental Health Of Emerging Adolescents, Vicki P. Winstead

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Life within the ecological context of a disadvantaged and disordered neighborhood is characterized by daily exposure to chronic stressors which are often outside the realm of control of the individual and have negative consequences for the mental health of its residents and in particular, adolescents Using data from Healthy Passages, a multilevel, multi-method longitudinal study which examines health trajectories of adolescents over a ten year period, this paper examines whether daily exposure to a threatening environment in disadvantaged and disordered neighborhoods lead to depression in young people who are on the verge of adolescence. The current study tested the relationships …


Study Of The Role Of The Amygdala In The Effects Of Stress On Sensory Processing Of The Urinary Bladder, Jennifer De Berry Jan 2010

Study Of The Role Of The Amygdala In The Effects Of Stress On Sensory Processing Of The Urinary Bladder, Jennifer De Berry

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Interstitial cystitis (IC) is a chronic visceral condition of the urinary bladder characterized by pelvic/suprapubic pain, and urinary frequency and urgency. There is no documented cause for IC, but a prominent role for stress in its pathophysiology and presentation are well-documented. In the clinical setting, IC pain-related symptomatology is exacerbated during periods of stress. Numerous laboratory studies of humans and animals have similarly demonstrated stress-induced visceral hypersensitivity. The amygdala is highly connected with physiological stress response systems and pain modulatory pathways, and its connectivity with these systems places it in a unique anatomical position for mediating the reciprocal relationship between …


Parental Well-Being And Child Outcomes Among School-Aged, Prematurely-Born Children., Desiree Maria De Jong Jan 2010

Parental Well-Being And Child Outcomes Among School-Aged, Prematurely-Born Children., Desiree Maria De Jong

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Children born prematurely are at a significantly higher risk than their full-term peers for developing cognitive, behavioral, attention, and executive functioning difficulties by the time they reach school-age. Parents of children born prematurely are also at greater risk for developing symptoms of depression and stress compared to parents of full-term children. However, the literature is conflicting with respect to whether or not parental well-being remains compromised by the time the preterm child reaches school-age. Additionally, much of the research examining this relationship is conducted prior to school-age, with little research beyond these years. A primary purpose of the current study …