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The Effect Of Temperature On The Rate Of Antibiotic Resistance Development In Vibrio Vulnificus, Amber Marie Richardson
The Effect Of Temperature On The Rate Of Antibiotic Resistance Development In Vibrio Vulnificus, Amber Marie Richardson
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Vibrio vulnificus is an environmentally encountered pathogen that humans may be exposed to through open wound contact with brackish waters or by ingestion of contaminated shellfish. In susceptible individuals, a V. vulnificus infection can spread rapidly, resulting in hospitalization, amputation, or even death. This bacterial species can cause aggressive infection, so treatment must often be aggressive as well. A typical treatment regimen includes combination therapy with a third-generation cephalosporin along with either a tetracycline or a fluoroquinolone. Although this method can work for now, antibiotic resistance is a looming threat that has emerged in many bacterial pathogens, including V. vulnificus. …
Environmental Specific Effects On Life History And Energy Metabolism Traits In A Permethrin Resistant Strain Of Anopheles Gambiae, Dennis Otali
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Widespread use of pyrethroids for control of malaria vectors together with use in agriculture for pest control has led to an increase in emergence of populations of pyrethroid resistant phenotypes. Insecticide resistance can likely alter vector development time, reproduction, behavior, and longevity, all of which can affect the potential for disease transmission. In this study we assessed whether the genetic modifications (kdr mutation, cytochrome P450 and esterase detoxification) in a permethrin resistant strain of An. gambiae influence traits related to fitness. The performances of these traits were compared between two strains of An. gambiae, one permethrin susceptible (ASEMBO1) and the …
The Comparison Of Mitochondrial Functions Of 2 Drosophila Species: Drosophila Ananassae And Drosophila Subobscura, Hye J. Shin
The Comparison Of Mitochondrial Functions Of 2 Drosophila Species: Drosophila Ananassae And Drosophila Subobscura, Hye J. Shin
All ETDs from UAB
Recently, it has been suggested that differences in mitochondrial function enabled Homo sapiens to migrate out of Africa by enabling humans to adapt to colder environments as they migrated to higher latitude areas. Through mitochondrial mutations that partially uncoupled oxidative phosphorylation, humans that moved to colder areas were able to generate more heat for better survival, while producing less energy. However, due to challenges in working with human populations, no specific studies have been able to show the existence of such differences in mitochondrial function within healthy humans. Because of numerous advantages of Drosophila as a developmental model, such as …