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Analyzing Tortuosity In Patterns Formed By Colonies Of Embryonic Stem Cells Using Topological Data Analysis, Jackie Driscoll
Analyzing Tortuosity In Patterns Formed By Colonies Of Embryonic Stem Cells Using Topological Data Analysis, Jackie Driscoll
Master's Theses
Pluripotent stem cells have been observed to segregate into Turing-like patterns during the early stages of Dox-inducible hiPSC differentiation. In this thesis, we de- velop a tool to quantify the tortuosity in the patterns formed by colonies of pluripo- tent stem cells using methods from topological data analysis. We use clustering techniques and the mapper algorithm to create simplicial complexes representing samples of cells and detail a method of evaluating the tortuosity of these complexes. We use the resulting persistence landscapes and their associated norms to evaluate experimental data and simulated data from an agent based model. This thesis finds …
The Commutant Of The Fourier–Plancherel Transform, Brianna Cantrall
The Commutant Of The Fourier–Plancherel Transform, Brianna Cantrall
Honors Theses
One can see that this matrix is unitary and has eigenvalues {1,−i,−1, I}, each of infinite multiplicity. Throughout the remainder of this thesis, we will convince the reader that the above linear transformation is actually the Fourier transform. We will compute the commutant, as well as its invariant subspaces. The key to do this relies on the Hermite polynomials. Why do we recast the Fourier transform from its well-known and well studied integral form to the matrix form shown above? As we will see, the matrix form allows us to efficiently discover the operator theory of the Fourier transform obfuscated …