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Uncovering Functional Relationships In Leukemia, Reginald Mcgee May 2017

Uncovering Functional Relationships In Leukemia, Reginald Mcgee

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Hiv Dynamics Following 3bnc117 Antibody Infusion, Samantha Erwin May 2017

Modeling Hiv Dynamics Following 3bnc117 Antibody Infusion, Samantha Erwin

Biology and Medicine Through Mathematics Conference

No abstract provided.


On The Analysis Of The Sir Epidemic Model For Small Networks: An Application In Hospital Settings, Martin Lopez-Garcia May 2017

On The Analysis Of The Sir Epidemic Model For Small Networks: An Application In Hospital Settings, Martin Lopez-Garcia

Biology and Medicine Through Mathematics Conference

No abstract provided.


Balanced Excitation And Inhibition Shapes The Dynamics Of A Neuronal Network For Movement And Reward, Anca R. Radulescu May 2017

Balanced Excitation And Inhibition Shapes The Dynamics Of A Neuronal Network For Movement And Reward, Anca R. Radulescu

Biology and Medicine Through Mathematics Conference

No abstract provided.


Oscillations In Epidemic Models With Spread Of Awareness, Ying Xin May 2017

Oscillations In Epidemic Models With Spread Of Awareness, Ying Xin

Biology and Medicine Through Mathematics Conference

No abstract provided.


Analyzing Sexual Transmission In The Spread Of The Zika Virus In Colombia, Victoria M. Kelley May 2017

Analyzing Sexual Transmission In The Spread Of The Zika Virus In Colombia, Victoria M. Kelley

Biology and Medicine Through Mathematics Conference

No abstract provided.


High Performance Computation Of Cardiac Models In Real-Time Using Webgl, Abouzar Kaboudian, Flavio H. Fenton May 2017

High Performance Computation Of Cardiac Models In Real-Time Using Webgl, Abouzar Kaboudian, Flavio H. Fenton

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Role Of E-Antigen In Hepatitiv B Virus Infection, Mirjam Sarah Kadelka May 2017

The Role Of E-Antigen In Hepatitiv B Virus Infection, Mirjam Sarah Kadelka

Biology and Medicine Through Mathematics Conference

No abstract provided.


Applying Fmri Complexity Analyses To The Single-Subject: A Case Study For Proposed Neurodiagnostics, Anca R. Radulescu, Emily R. Hannon May 2017

Applying Fmri Complexity Analyses To The Single-Subject: A Case Study For Proposed Neurodiagnostics, Anca R. Radulescu, Emily R. Hannon

Biology and Medicine Through Mathematics Conference

No abstract provided.


An Interdisciplinary Approach To Computational Neurostimulation, Madison Guitard May 2017

An Interdisciplinary Approach To Computational Neurostimulation, Madison Guitard

Biology and Medicine Through Mathematics Conference

No abstract provided.


Noisy Neural Oscillators With Intrinsic And Network Heterogeneity, Kyle P. Wendling, Cheng Ly May 2017

Noisy Neural Oscillators With Intrinsic And Network Heterogeneity, Kyle P. Wendling, Cheng Ly

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Large Reaction-Diffusion Model For Cell Polarization In Yeast, Marissa Renardy May 2017

A Large Reaction-Diffusion Model For Cell Polarization In Yeast, Marissa Renardy

Biology and Medicine Through Mathematics Conference

No abstract provided.


Evolution Of Influenza H3n2: A Random Walk In High Dimensions, James R. Moore May 2017

Evolution Of Influenza H3n2: A Random Walk In High Dimensions, James R. Moore

Biology and Medicine Through Mathematics Conference

No abstract provided.


A Model For A Parameter Related To Free Virus Production From Infected Target Cells, Evan C. Haskell May 2017

A Model For A Parameter Related To Free Virus Production From Infected Target Cells, Evan C. Haskell

Biology and Medicine Through Mathematics Conference

No abstract provided.


The Kinetics Of Type I Interferons During Influenza Virus Infection, Margaret A. Myers May 2017

The Kinetics Of Type I Interferons During Influenza Virus Infection, Margaret A. Myers

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Modeling Of Normal And Abnormal Responses To The Valsalva Maneuver, Eric Benjamin Randall May 2017

Mathematical Modeling Of Normal And Abnormal Responses To The Valsalva Maneuver, Eric Benjamin Randall

Biology and Medicine Through Mathematics Conference

No abstract provided.


Dynamics Of Fluorescent Imaging In Glob-Driven Breakup, Lan Zhong, Christiaan Ketelaar, Richard J. Braun, Carolyn G. Begley, Peter Ewen King-Smith May 2017

Dynamics Of Fluorescent Imaging In Glob-Driven Breakup, Lan Zhong, Christiaan Ketelaar, Richard J. Braun, Carolyn G. Begley, Peter Ewen King-Smith

Biology and Medicine Through Mathematics Conference

No abstract provided.


Control Policies And Sensitivity Analysis In A Cutaneous Leishmaniasis Model: A Case Study In Cusco Region, Peru., Rocio M. Caja-Rivera, Ignacio Barradas May 2017

Control Policies And Sensitivity Analysis In A Cutaneous Leishmaniasis Model: A Case Study In Cusco Region, Peru., Rocio M. Caja-Rivera, Ignacio Barradas

Biology and Medicine Through Mathematics Conference

No abstract provided.


Code For "Noise-Enhanced Coding In Phasic Neuron Spike Trains", Cheng Ly, Brent D. Doiron Jan 2017

Code For "Noise-Enhanced Coding In Phasic Neuron Spike Trains", Cheng Ly, Brent D. Doiron

Statistical Sciences and Operations Research Data

This zip file contains Matlab scripts and ode (XPP) files to calculate the statistics of the models in "Noise-Enhanced Coding in Phasic Neuron Spike Trains". This article is published in PLoS ONE.


A Two-Species Stage-Structured Model For West Nile Virus Transmission, Taylor A. Beebe, Suzanne L. Robertson Jan 2017

A Two-Species Stage-Structured Model For West Nile Virus Transmission, Taylor A. Beebe, Suzanne L. Robertson

Mathematics and Applied Mathematics Publications

We develop a host–vector model of West Nile virus (WNV) transmission that incorporates multiple avian host species as well as host stage-structure (juvenile and adult stages), allowing for both species-specific and stage-specific biting rates of vectors on hosts. We use this ordinary differential equation model to explore WNV transmission dynamics that occur between vectors and multiple structured host populations as a result of heterogeneous biting rates on species and/or life stages. Our analysis shows that increased exposure of juvenile hosts generally results in larger outbreaks of WNV infectious vectors when compared to differential host species exposure. We also find that …


A Theoretical Framework For Analyzing Coupled Neuronal Networks: Application To The Olfactory System, Andrea K. Barreiro, Shree Hari Gautam, Woodrow L. Shew, Cheng Ly Jan 2017

A Theoretical Framework For Analyzing Coupled Neuronal Networks: Application To The Olfactory System, Andrea K. Barreiro, Shree Hari Gautam, Woodrow L. Shew, Cheng Ly

Mathematics and Applied Mathematics Publications

Determining how synaptic coupling within and between regions is modulated during sensory processing is an important topic in neuroscience. Electrophysiological recordings provide detailed information about neural spiking but have traditionally been confined to a particular region or layer of cortex. Here we develop new theoretical methods to study interactions between and within two brain regions, based on experimental measurements of spiking activity simultaneously recorded from the two regions. By systematically comparing experimentally-obtained spiking statistics to (efficiently computed) model spike rate statistics, we identify regions in model parameter space that are consistent with the experimental data. We apply our new technique …


A Mathematical System For Human Implantable Wound Model Studies, Salomonsky Paul-Michael, Rebecca Segal Jan 2017

A Mathematical System For Human Implantable Wound Model Studies, Salomonsky Paul-Michael, Rebecca Segal

Mathematics and Applied Mathematics Publications

In this work, we present a mathematical model, which accounts for two fundamental processes involved in the repair of an acute dermal wound. These processes include the inflammatory response and fibroplasia. Our system describes each of these events through the time evolution of four primary species or variables. These include the density of initial damage, inflammatory cells, fibroblasts and deposition of new collagen matrix. Since it is difficult to populate the equations of our model with coefficients that have been empirically derived, we fit these constants by carrying out a large number of simulations until there is reasonable agreement between …


Management Of Invasive Allee Species, David Chan, C. M. Kent, D. M. Johnson Jan 2017

Management Of Invasive Allee Species, David Chan, C. M. Kent, D. M. Johnson

Mathematics and Applied Mathematics Publications

In this study, we use a discrete, two-patch population model of an Allee species to examine different methods in managing invasions. We first analytically examine the model to show the presence of the strong Allee effect, and then we numerically explore the model to test the effectiveness of different management strategies. As expected invasion is facilitated by lower Allee thresholds, greater carrying capacities and greater proportions of dispersers. These effects are interacting, however, and moderated by population growth rate. Using the gypsy moth as an example species, we demonstrate that the effectiveness of different invasion management strategies is context-dependent, combining …


The Effects Of Disturbance And Species Specific Interactions On Diversity In An Agent Based Forest Simulation, Matthew E. Mills Jan 2017

The Effects Of Disturbance And Species Specific Interactions On Diversity In An Agent Based Forest Simulation, Matthew E. Mills

Theses and Dissertations

In ecology literature, there is much data which suggests that conspecific negative density dependence (CNDD) and abiotic disturbances increase biodiversity in forests. This thesis elucidates the notion that not only do these two forces increase diversity, but they may also interact with one another in order to achieve higher levels of biodiversity. Abiotic disturbances, like fires and hurricanes, can indirectly impact conspecific effects because when these forces remove individuals from the landscape, the role of the conspecific effects will change. The interaction of these two factors in biodiversity are explored in an agent based forest simulation through a resource surface. …


Mathematical Models Of The Inflammatory Response In The Lungs, Sarah B. Minucci Jan 2017

Mathematical Models Of The Inflammatory Response In The Lungs, Sarah B. Minucci

Theses and Dissertations

Inflammation in the lungs can occur for many reasons, from bacterial infections to stretch by mechanical ventilation. In this work we compare and contrast various mathematical models for lung injuries in the categories of acute infection, latent versus active infection, and particulate inhalation. We focus on systems of ordinary differential equations (ODEs), agent-based models (ABMs), and Boolean networks. Each type of model provides different insight into the immune response to damage in the lungs. This knowledge includes a better understanding of the complex dynamics of immune cells, proteins, and cytokines, recommendations for treatment with antibiotics, and a foundation for more …


Computational Fluid Dynamics In A Terminal Alveolated Bronchiole Duct With Expanding Walls: Proof-Of-Concept In Openfoam, Jeremy Myers Jan 2017

Computational Fluid Dynamics In A Terminal Alveolated Bronchiole Duct With Expanding Walls: Proof-Of-Concept In Openfoam, Jeremy Myers

Theses and Dissertations

Mathematical Biology has found recent success applying Computational Fluid Dynamics (CFD) to model airflow in the human lung. Detailed modeling of flow patterns in the alveoli, where the oxygen-carbon dioxide gas exchange occurs, has provided data that is useful in treating illnesses and designing drug-delivery systems. Unfortunately, many CFD software packages have high licensing fees that are out of reach for independent researchers. This thesis uses three open-source software packages, Gmsh, OpenFOAM, and ParaView, to design a mesh, create a simulation, and visualize the results of an idealized terminal alveolar sac model. This model successfully demonstrates that OpenFOAM can be …


Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri Jan 2017

Network Analytics For The Mirna Regulome And Mirna-Disease Interactions, Joseph Jayakar Nalluri

Theses and Dissertations

miRNAs are non-coding RNAs of approx. 22 nucleotides in length that inhibit gene expression at the post-transcriptional level. By virtue of this gene regulation mechanism, miRNAs play a critical role in several biological processes and patho-physiological conditions, including cancers. miRNA behavior is a result of a multi-level complex interaction network involving miRNA-mRNA, TF-miRNA-gene, and miRNA-chemical interactions; hence the precise patterns through which a miRNA regulates a certain disease(s) are still elusive. Herein, I have developed an integrative genomics methods/pipeline to (i) build a miRNA regulomics and data analytics repository, (ii) create/model these interactions into networks and use optimization techniques, motif …


Series Solutions Of Polarized Gowdy Universes, Doniray Brusaferro Jan 2017

Series Solutions Of Polarized Gowdy Universes, Doniray Brusaferro

Theses and Dissertations

Einstein's field equations are a system of ten partial differential equations. For a special class of spacetimes known as Gowdy spacetimes, the number of equations is reduced due to additional structure of two dimensional isometry groups with mutually orthogonal Killing vectors. In this thesis, we focus on a particular model of Gowdy spacetimes known as the polarized T3 model, and provide an explicit solution to Einstein's equations.