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Estradiol Interactions With Dopamine Antagonists In Mares: Prolactin Secretion And Reproductive Traits, Kristian Kandis Kelley

LSU Master's Theses

Two experiments studied the effects of pretreatment with estradiol benzoate before treatment with a dopamine antagonist on prolactin secretion and reproductive traits in mares during 1) the seasonal anovulatory period and 2) the normal breeding season. Experiment 1 was performed in winter with 17 mares selected for low follicular activity. Nine mares received estradiol benzoate injections every other day for a total of 10 injections; 8 mares received similar injections of vehicle. Ten days after onset of injections, all mares were placed on a daily injections of sulpiride (250 mg) for 45 d or until ovulation. Plasma prolactin concentrations were …