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Animal Sciences

LSU Master's Theses

Theses/Dissertations

2011

Horses

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Intravenous Injection Of Insulin For Measuring Insulin Sensitivity In Horses: Effects Of Epinephrine, Feeding Regimen, And Supplementation With Cinnamon For Fish Oil, Lisa Rosalee Earl Jan 2011

Intravenous Injection Of Insulin For Measuring Insulin Sensitivity In Horses: Effects Of Epinephrine, Feeding Regimen, And Supplementation With Cinnamon For Fish Oil, Lisa Rosalee Earl

LSU Master's Theses

Seven experiments were performed to assess the use of glucose responses to insulin injections as a means of estimating insulin sensitivity in horses; to compare the insulin sensitivities of normal horses vs. those displaying hyperleptinemia; and to put this method into practical application. Experiment 3.1 examined dose-responses in mares of potentially different insulin sensitivities. Recombinant human insulin was injected at doses of 8, 20, 50, and 125 mU/kg BW, as needed, to estimate the dose of insulin causing a 50% decrease in glucose concentrations (ED50). Five mares each of low leptin concentrations (LL) and low BCS, LL and high BCS, …