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Animal Sciences

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University of Tennessee, Knoxville

Masters Theses

E. coli

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Characterizing The Transfer Of Bacterial Antibiotic Resistance Genes Across Generations Of Swine, Kimberly Nakia Garner May 2002

Characterizing The Transfer Of Bacterial Antibiotic Resistance Genes Across Generations Of Swine, Kimberly Nakia Garner

Masters Theses

Sows and pigs were used to characterize the origin, transfer and persistence of bacterial resistance in swine. Effects of sow’s previous exposure to antibiotics and subsequent use of antibiotics in their pigs on antibiotic resistance of Salmonella enterica Typhimurium, Enterococcus faecalis, and E. coli were determined. Eight pregnant sows were divided into two groups, with four sows receiving oxytetracycline and four sows receiving no antibiotics. Fecal samples were obtained from sows prior to antibiotic exposure, and at 1- week intervals until pigs were weaned. Weaned pigs were challenged with Salmonella Typhimurium containing a nalidixic acid. Pigs from each sow …


Effects Of Management And Environmental Conditions On Antibiotic Resistance In Bacteria Associated With Swine, Patricia Cullen Aug 2001

Effects Of Management And Environmental Conditions On Antibiotic Resistance In Bacteria Associated With Swine, Patricia Cullen

Masters Theses

Weaned pigs (n=58) were challenged with nalidixic resistant Salmonella enterica serotype Typhimurium and separated into eight treatments to determine the effects of various environmental and management conditions on the development of antibiotic resistance among pathogenic and commensal bacteria. Apramycin sulfate was administered in the feed (150g/ton) two days postchallenge for a period of 14 days with the exception of one control group. Treatments included: control without apramycin (control-1); control with apramycin (control-2); and apramycin plus either cold stress, heat stress, overcrowding, intermingling, poor sanitation, and intervention with oxytetracycline (100 ug / ton). Treatments were applied 5 days post initial antibiotic …