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Pharmacokinetics Of Cbd Supplementation In Horses: Single Dose Vs. Long-Term Feeding, Madilyn Adamchik May 2023

Pharmacokinetics Of Cbd Supplementation In Horses: Single Dose Vs. Long-Term Feeding, Madilyn Adamchik

Honors College Theses

Research about supplemental feeding of cannabidiol (CBD) to horses is still in its early stages, but many horse owners are feeding CBD supplements for supposed benefits, including behavior and pain management. Cannabinoids work through the endocannabinoid system to modulate nervous and hormonal actions in the body, working to maintain a healthy homeostatic balance. Safety and efficacy have been tested for dosages of up to 500 mg of CBD per day for horses, but further research about the pharmacokinetics based on dosage amount and form of CBD are still needed. The objectives of this study were to evaluate the pharmacokinetics of …


Pharmacokinetics Of Single Feeding Of Cannabidiol In Cattle: A Pilot Study, Haley Cornette Apr 2023

Pharmacokinetics Of Single Feeding Of Cannabidiol In Cattle: A Pilot Study, Haley Cornette

Honors College Theses

Cannabidiol (CBD) is a substance that has been used in complementary medicine for many years. However, modern medicine has little knowledge of how this substance is utilized and metabolized in ruminant animals. Regulations on quality assurance and use in animals are lacking, and CBD supplementation in livestock is not approved. If CBD supplements can be shown to be safe and effective, detection in the animal will be important for determining regulation of use. A withdrawal period can then be established to allow time for deterioration of product to safe levels before livestock products enter human markets. This study sought to …


Comparison Of Corticosterone Concentrations Between Serum And Fecal Samples As A Measure Of Stress In Male Broilers., Kayla Weinacht Jan 2023

Comparison Of Corticosterone Concentrations Between Serum And Fecal Samples As A Measure Of Stress In Male Broilers., Kayla Weinacht

Murray State Theses and Dissertations

Stress has long been a topic of interest in the poultry industry due to its potential negative effects on chicken health and production of both eggs and meat. With increased global growth in egg and broiler production, more attention has been paid to the stressors that affect chickens in modern poultry operations, particularly environmental temperature and stocking density. Improving quantitative measurement of stress is always needed in poultry welfare research. In most studies, blood serum is measured for corticosterone, one of the biomarker hormones associated with stress in chickens. Methods of collecting blood serum are by their nature disruptive to …