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Articles 1 - 12 of 12
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Quantifying The Respiratory Plasticity Of Common Fishes Of The Indian River Lagoon, Logan Exton
Quantifying The Respiratory Plasticity Of Common Fishes Of The Indian River Lagoon, Logan Exton
Honors Theses
Increasing water temperatures resulting from global climate change introduce new energetic demands for marine organisms. Higher energy input will be required to cope with a subsequently higher metabolic rate, affecting all aspects of an individual’s life and therefore their survival. Because estuaries act as a link between rivers and oceans, they and their inhabitants are considered to be the most threatened by climate change. Therefore, it is crucial to understand how these organisms will respond to increased stressors due to climate change. Checkered pufferfish (Sphoeroides testudineus) are among the most common teleost fish in the Indian River Lagoon, …
Evaluating The Impact Of Temperature And Artificial Light At Night On The Growth, Swimming Performance, And Corticosterone Levels Of Southern Leopard Frog (Lithobates Sphenocephalus) Tadpoles, Skylar Alexander
Honors Theses
Anthropogenic activities caused by urbanization have considerably altered our world’s ecosystems which has led to a global amphibian population decline. Encroaching and unyielding urbanization by humans has contributed to a rise in artificial light at night due to light pollution as well as increased temperature due to climate change. Both rising temperatures and artificial light at night (ALAN) have been shown to individually have negative effects on amphibian physiology such as increased stress and decreased behavior. However, due to the drastic nature of human imposition, amphibians typically encounter these anthropogenic stressors in combination. Therefore, it is important to understand how …
Analysis Of Wild Rodent Gut Microbiota As A Function Of Exposure To Ticks And Tick-Borne Pathogens, Joshua Pandian
Analysis Of Wild Rodent Gut Microbiota As A Function Of Exposure To Ticks And Tick-Borne Pathogens, Joshua Pandian
Honors Theses
Due to advances in high-throughput parallel sequencing, researchers have conducted novel studies exploring relationships between microbiome compositions and different aspects of organism health. Some of these studies have shown that the gut microbiome of rodent models has effects on organism health and behavior and that infection with pathogens and the composition of the skin microbiome are linked to changes in gut microbiome composition. While previous studies have shown how vector microbiota impact vector behavior and pathogen transmission, the effect vectors have on reservoir species microbiomes has been a less prominent focus. We were interested in the relationships between tick parasitism, …
Developing A Novel Place Preference Assay To Compare Drosophila Species Over Time, Martha M. Brinson
Developing A Novel Place Preference Assay To Compare Drosophila Species Over Time, Martha M. Brinson
Honors Theses
Across phylogeny, integration of external factors, memory, and internal states of the organism dictate organismal behavior and mechanisms. The underlying genetic components can affect these behaviors such as in genomic changes arising from speciation. In this thesis, a new place preference assay was evaluated in the analysis and investigation of two species of Drosophila flies (D. melanogaster and D. simulans) to measure similarities and differences and their attraction to two different food substrates. Sleep and circadian measurements were also recorded during experimentation. The Drosophila Activity Monitor 5M (DAM5M) System and Sleep Circadian Analysis MATLAB Program (SCAMP) analysis were …
Characterizing The Roles Of Cannabinoid Receptor 1 & 2 In Zebrafish Behavior, Metabolism, And Seizure-Induced Activity, Kayci Kimmons
Characterizing The Roles Of Cannabinoid Receptor 1 & 2 In Zebrafish Behavior, Metabolism, And Seizure-Induced Activity, Kayci Kimmons
Honors Theses
Epileptic disorders like Dravet Syndrome require novel studies to determine the most ideal treatment. New research linking the endocannabinoid system (ECS) to epileptic disorders is arising, but there is still much to be discovered about the function and regulatory impact of the endocannabinoid system and its receptors in epilepsies like Dravet. In this study, knockout models of larval and adult zebrafish (Danio rerio) were used to investigate the roles of cannabinoid receptors 1 & 2 in behavior, brain mitochondrial metabolism, and seizure-induced activity following exposure to THC and CBD. Larval zebrafish which lacked cannabinoid receptor 1 exhibited increased …
Conditioned Territory Defense In Madagascar Hissing Cockroaches (Gromphadorhina Portentosa), Macy R. Albaitis
Conditioned Territory Defense In Madagascar Hissing Cockroaches (Gromphadorhina Portentosa), Macy R. Albaitis
Honors Theses
In male blue gourami fish (Trichogaster trichopterus), signaled presentation of a male rival produces an aggressive conditioned response that results in an increased likelihood of the male winning the contest (Hollis, 1984). I replicated this classic study in a species that also shows territorial aggression: the Madagascar hissing cockroach (MHC; Gromphadorhina portentosa). During training, four adult male MHCs were designated as “CS+” animals and received a light (NS) followed by visual access to a rival male (US). Simultaneously, another group of four adult male MHCs designated as “UNC” animals received the light (NS) and visual access to a …
Responses To Fine Particulate Matter (Pm2.5) Exposures In Two Wild-Type Zebrafish Strains, Connor Necaise
Responses To Fine Particulate Matter (Pm2.5) Exposures In Two Wild-Type Zebrafish Strains, Connor Necaise
Honors Theses
Atmospheric fine particulate matter (PM2.5) exposure poses great health risks across the globe, causing both acute and chronic illnesses in humans. Therefore, a more complete understanding of the mechanisms in which PM2.5 induces these adverse health effects is urgently needed. Oxidative stress due to PAHs and other common components of PM2.5 is a proposed mechanism for its adverse health effects. However, little is known about the actual mechanisms of PM2.5 damage in humans. This study aimed to distinguish behavioral differences in two lines of zebrafish (AB & 5D) as a result of developmental exposure to …
The Effect Of Agkistrodon Contortrix And Crotalus Horridus Venom Toxicity On Strike Locations With Live Prey., Chase Giese
The Effect Of Agkistrodon Contortrix And Crotalus Horridus Venom Toxicity On Strike Locations With Live Prey., Chase Giese
Honors Theses
This paper aims to uncover if there is a significant difference in the strike location of snake species that have different values of LD50% venom. It is thought that most snakes strike their prey in the anterior (head) area in order for their venom to work quicker in killing them. Venom toxicity is measured by its LD50% value, which is the amount of venom, in mg/kg, to kill 50% of a test population. The Copperhead has an LD50% value of 10.9 mg/kg, and the Timber Rattlesnake has an LD50% value of 1.64 mg/kg. The hypothesis was that if venom toxicity …
The Relationship Between Glucocorticoids And The Humoral Immune Response To Mycoplasma Gallisepticum Challenges In Eastern Bluebirds, Joshua Smith
Honors Theses
Numerous studies have examined relationships between adrenal glucocorticoids and the immune system’s ability to fight disease. The relationship can vary, with glucocorticoids having either stimulatory or inhibitory effects. The pathogenic bacterium Mycoplasma gallisepticum (MG) elicits an adaptive immune response in birds, in which B cells produce MG-specific antibodies to fight the infection and prevent reoccurrence. Previous research found that Eastern Bluebirds that produce the most antibodies in response to MG infection also have the highest glucocorticoid levels. This finding led to the current study investigating whether corticosterone, the primary glucocorticoid in birds, stimulates production of antibodies in response to immune …
Impacts Of Embryonic Exposure To Cannabidiol Or ∆9-Tetrahydrocannabinol On Zebrafish (Danio Rerio) Frailty In F0 And F1 Generations, Anika Faruque
Impacts Of Embryonic Exposure To Cannabidiol Or ∆9-Tetrahydrocannabinol On Zebrafish (Danio Rerio) Frailty In F0 And F1 Generations, Anika Faruque
Honors Theses
Exposure to cannabinoids during critical development periods has increased with epileptic children being commonly prescribed CBD for seizures and pregnant women taking it recreationally. Many studies have been done on the possible benefits and drawbacks of cannabinoid exposure on the human brain, but not much is known about how it can affect the developing brain long-term. To see the potential adverse effects of cannabinoid exposure during critical stages of development and discover potential developmental origins of disease in consuming cannabinoids during embryogenesis, zebrafish embryos (6-96 hours post fertilization) were exposed to varying concentrations of CBD (0.02, 0.1, 0.5 µM), THC …
The Effects Of Phosphate On The Metamorphosis Of Larval Western Barred Tiger Salamanders (Ambystoma Mavortium), Lexy Polivanov
The Effects Of Phosphate On The Metamorphosis Of Larval Western Barred Tiger Salamanders (Ambystoma Mavortium), Lexy Polivanov
Honors Theses
This investigation will collect data to assist in determining if elevated aquatic phosphate levels affects the metamorphosis rate of larval western barred tiger salamanders (Ambystoma mavortium). Monoammonium phosphate fertilizers are being used on crops in Nebraska (NDA, 2017). This area lines up with the area the western barred tiger salamanders are disappearing from (Damme, 2018). Monoammonium phosphate is made up of nitrogen and phosphate. There have been several studies showing how nitrogen is harmful to amphibians such as this salamander (Griffis-Kyle, 2007) (Griffis-Kyle & Richtie, 2007), but there have not been many showing how phosphate affects amphibian’s metamorphosis …
Establishing A Mouse Model For The Study Of Podocyte Regeneration After Injury, John A. Gomez
Establishing A Mouse Model For The Study Of Podocyte Regeneration After Injury, John A. Gomez
Honors Theses
Podocytes are vital, specialized kidney cells that are post-mitotic and cannot proliferate. Nevertheless, regeneration of podocytes after low-level ablation from a presently unidentified stem cell pool has been observed. The objective of this study was to establish a mouse model for the study of this regeneration process. Two transgenic mice were developed, the first of which possessed a tomato-reporter transgene for the assessment of podocyte turnover. Adriamycin was used to induce podocyte damage in this mouse. The second transgenic mouse possessed the tomato-reporter transgene as well as transgene allowing for the diphtheria toxin inducible (iDTR) ablation of podocytes. Dosage tests …