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Identification, Creation, And Characterization Of Bio-Based Antifreeze Agents, Joshua Samuel Saad

Masters Theses

Ice recrystallization is a key problem leading to quality deterioration of frozen foods and biomedical materials. Molecules possessing ice recrystallization inhibition (IRI) activity can control ice crystal size after freezing, reducing the degree of freezing-induced damage. While these IRI active molecules have shown promise in maintaining the quality of frozen foods, their slow discovery, limited creation strategies, and lack of mechanistic understanding limit their hypothesis-driven design. In this work, we address these above-stated needs required for the streamlined implementation of these materials into frozen systems by the creation of a machine-learning-based IRI screening method, the development of a new IRI …