Chemotherapeutic Drug Cytotoxicity Measurement With A 3d Biomimetic Microfluidic Device And Computational Fluid Dynamics Model, 2018 Virginia Polytechnic Institute and State University
Chemotherapeutic Drug Cytotoxicity Measurement With A 3d Biomimetic Microfluidic Device And Computational Fluid Dynamics Model, Maryam Moarefian, Caroline Jones, Luke Achenie, Danesh Tafti
Biology and Medicine Through Mathematics Conference
No abstract provided.
Modeling Of Swimming Cells From Nano-Scale To Micro-Scale, 2018 Washinton University in St. Louis
Modeling Of Swimming Cells From Nano-Scale To Micro-Scale, Yicheng Zhao
Engineering and Applied Science Theses & Dissertations
Certain human genetic diseases -- primary ciliary dyskinesia, infertility, and hydrocephalus -- are characterized by changes in beat frequency and waveform of cilia and flagella. Chlamydomonas reinhardtii, which is a single-cell green alga about ten micrometers in diameter that swims with two flagella, serves as an excellent biological model because its flagella share the same structure and genetic background as mammalian cilia and flagella. This study uses the finite element method to investigate the behavior of C. reinhardtii swimming from nano-scale to micro-scale. At the device-level, micro-scale modeling indicates that well-designed acoustic microfluidic devices can be used to trap groups of C ...
Digital Enhancement Of Analog Measurement Systems For Temperature Compensation Of Strain Gages, 2018 University of Texas at Tyler
Digital Enhancement Of Analog Measurement Systems For Temperature Compensation Of Strain Gages, Islombek Karimov
Electrical Engineering Theses
Generally known temperature compensation techniques for strain gages (like the use of a dummy gage or the implementation of half- and full-bridge configurations) are not applicable to all strain-measurement situations and cannot fully compensate for all sources of error. Digital Enhancement of Analog Measurement Systems presents a universal method of corrections for these effects in which temperature is measured independently of other variables and ex post facto corrections are computed and applied to digitized readings of the analog measurement system.
A single, linear-pattern strain gage, self-temperature-compensated for steel 1018, has been utilized in a quarter-bridge to measure tensile strain in ...
Baseline Data From Servo Motors In A Robotic Arm For Autonomous Machine Fault Diagnosis, 2018 University of Arkansas, Fayetteville
Baseline Data From Servo Motors In A Robotic Arm For Autonomous Machine Fault Diagnosis, Jacob Brown
Mechanical Engineering Undergraduate Honors Theses
Fault diagnosis can prolong the life of machines if potential sources of failure are discovered and corrected before they occur. Supervised machine learning, or the use of training data to enable machines to discover these faults on their own, makes failure prevention much easier. The focus of this thesis is to investigate the feasibility of creating datasets of various faults at both the component and system level for a servomotor and a compatible robotic arm, such that this data can be used in machine learning algorithms for fault diagnosis. The faults induced at the component level in different servomotors include ...
Microheater Array Powder Sintering (Maps) For Printing Flexible Electronics, 2018 University of Arkansas, Fayetteville
Microheater Array Powder Sintering (Maps) For Printing Flexible Electronics, Nicholas Holt
Theses and Dissertations
Microheater array powder sintering (MAPS) is a novel additive manufacturing process that uses an array of microheaters to selectively sinter powder particles. MAPS shows great promise as a new method of printing flexible electronics by enabling digital curing of conductive inks on a variety of substrates. MAPS operation relies on establishing a precision air gap of a few microns between an array of microheaters, which can reach temperatures of 600°C, and a layer of conductive ink which can be deposited onto a flexible substrate. This system presents challenges, being: the fabrication of a microheater that can reach suitable temperatures ...
Fluid Phase Separation Via Nanochannel Array, 2018 University of Arkansas, Fayetteville
Fluid Phase Separation Via Nanochannel Array, John Lee
Theses and Dissertations
Microelectromechanical systems (MEMS) and nanoelectromechanical systems (NEMS) generate ideas and techniques for creating new devices at the micro/nano scale. This dissertation study designed a gas generator system utilizing nanochannels for phase separation that is useful for micro-pneumatic actuators, micro-valves, and micro-pumps. The new gas generator has the potential to be an integral part of a propulsion system for small-scale satellites. Nano/picosatellites have limited orientation capability partly due to the current limitations of microthruster devices. Development of a self-contained micro propulsion system enables dynamic orbital maneuvering of pico- and nano-class satellites.
Additionally, the new gas generator utilizes a high ...
Numerical Simulation Of A High Strain Rate Biaxial Compression Apparatus, 2018 Washington University in St. Louis
Numerical Simulation Of A High Strain Rate Biaxial Compression Apparatus, Michael Lagieski
Engineering and Applied Science Theses & Dissertations
Few experimental methods today are capable of exploring the strength of materials at high strain rates (105 s-1). Those that are capable, such as the Split Hopkinson Bar, Taylor Anvil and Plate Impact suffer from instability and are generally limited to one dimensional wave propagation. Of particular interest is material response under biaxial compression, similar to that seen in inertial confinement fusion. Laser fusion fuel pellets typically undergo large strain rates as well as plastic deformation and non-linear behavior. This work briefly outlines an experimental procedure designed to replicate these large strain rates under biaxial compression using spherical ...
Fabrication Of 3d Conjugated Polymer Structures Via Vat Polymerization Additive Manufacturing, 2018 The University of Western Ontario
Fabrication Of 3d Conjugated Polymer Structures Via Vat Polymerization Additive Manufacturing, Andrew T. Cullen
Electronic Thesis and Dissertation Repository
Conjugated polymers are a class of electromechanically active materials that can produce motion in response to an electric potential. This motion can be harnessed to perform mechanical work, and therefore these materials are particularly well suited for use as sensors and actuators in microelectromechanical systems. Conventional methods to fabricate conjugated polymer actuators result in planar morphologies that limit fabricated devices to simplistic linear or bending actuation modes. To overcome this limitation, this work develops a conjugated polymer formulation and associated additive manufacturing method capable of realizing three-dimensional conductive polymer structures. A light-based additive manufacturing technique known as vat polymerization is ...
Design Of Force Versus Displacement Test Stand, 2018 Western Michigan University
Design Of Force Versus Displacement Test Stand, Andrew Fritchley
Performing mechanical design around sensors is a critical skill which all engineering students should be familiar with. Of equal importance is gathering and correctly interpreting electrical data from engineering tests. The aim of this project is to design a force versus displacement test stand for applications related to the measurement of spring force-displacement correlation. The design uses a strain gauge load cell, and a magnetic linear encoder to provide accurate, repeatable force and travel measurements. A mechanical design to mount each sensor was created based initial project constraints. Finite element analysis was performed on all critical components to ensure that ...
Optimization Of Microfluidic Chip Fabrication Via Femtosecond Laser Ablation, 2018 University of South Carolina
Optimization Of Microfluidic Chip Fabrication Via Femtosecond Laser Ablation, Kenneth Aycock
Microfluidic devices have become staple tools in biomedical research and have a promising future as low cost, point-of-care (POC) diagnostic devices. Despite the advancements in microfluidic device technology, the manipulation and fabrication of these systems can be tedious and expensive. Repeatable techniques in which computer-aided designs are translated into microfluidic systems in a matter of minutes are highly desirable both for researchers and manufacturers. Laser ablation of tape substrates has shown promise in producing cost-effective, rapidly manipulable devices, but the work done thus far has utilized continuous wave lasers that perform suboptimally due to the relatively short wavelengths used and ...
Superpositioning High Power Lasers For Mid-Air Image Formation, 2018 University of Nebraska at Omaha
Superpositioning High Power Lasers For Mid-Air Image Formation, Auston Viotto
Student Research and Creative Activity Fair
This research evaluates different methods to create voxels, 3-dimensional pixels, in air without the need for special glasses or reflections off of surfaces. Research on the advantages of superimposing or the culmination, focusing, of laser light will be conducted. The point of superpositioning/culmination will be evaluated by the brightness of the voxel due to the Rayleigh Scatter Effect. The voxel’s brightness is dependent on the laser output strength and inversely proportional to its wavelength. Once a superimposed/culminated voxel has been created in the lab the next step will be to manipulate the location of the voxel ...
Electroosmotic Flow Of Viscoelastic Fluid In A Nanoslit, 2018 Old Dominion University
Electroosmotic Flow Of Viscoelastic Fluid In A Nanoslit, Lanju Mei, Hongna Zhang, Hongxia Meng, Shizhi Qian
Mechanical & Aerospace Engineering Faculty Publications
The electroosmotic flow (EOF) of viscoelastic fluid in a long nanoslit is numerically studied to investigate the rheological property effect of Linear Phan-Thien-Tanner (LPTT) fluid on the fully developed EOF. The non-linear Poisson-Nernst-Planck equations governing the electric potential and the ionic concentration distribution within the channel are adopted to take into account the effect of the electrical double layer (EDL), including the EDL overlap. When the EDL is not overlapped, the velocity profiles for both Newtonian and viscoelastic fluids are plug-like and increase sharply near the charged wall. The velocity profile resembles that of pressure-driven flow when the EDL is ...
Microfluidic Technology And Application In Urinal Analysis, 2018 Louisiana State University and Agricultural and Mechanical College
Microfluidic Technology And Application In Urinal Analysis, Jiwen Xiang
LSU Doctoral Dissertations
Microfluidic technology offers numerous advantages in minimizing and integrating the traditional assays. However, the lack of efficient control components of the microfluidic systems has been hindering the widely commercialization of the technology. The research work in this dissertation focused on the development of effective control components for microfluidic applications.
A linear peristaltic pump was firstly designed, fabricated, and tested for conventional microfluidics by synchronously compressing the microfluidic channel with a miniature cam-follower system in Chapter 2. The miniature cam-follower system and microfluidic chip was prototyped using three-dimensional (3D) printing technology and soft lithography technology. Results from experimental test showed that ...
Electrical Stimulus Controlled Binding/Unbinding Of Human Thrombin-Aptamer Complex, 2018 Iowa State University
Electrical Stimulus Controlled Binding/Unbinding Of Human Thrombin-Aptamer Complex, Pranav Shrotriya, Agnivo Gosai, Xiao Ma, Ganesh Balasubraminian
The binding/unbinding of the human thrombin and its 15-mer single stranded DNA aptamer, under the application of external stimulus in the form of electrostatic potential/electric field, is investigated by a combination of continuum analysis and atomistic molecular dynamics simulation. In agreement with the experiments that demonstrate the influence of electrostatic potential on the thrombin/aptamer complex, our computations show that the application of positive electric field successfully unbinds the thrombin from the aptamer. Results from umbrella sampling simulations reveal that there is a decrease in the free energy of binding between the thrombin and aptamer in presence of ...
Pressure-Driven Stabilization Of Capacitive Deionization, 2018 University of Kentucky
Pressure-Driven Stabilization Of Capacitive Deionization, Landon S. Caudill
Theses and Dissertations--Mechanical Engineering
The effects of system pressure on the performance stability of flow-through capacitive deionization (CDI) cells was investigated. Initial data showed that the highly porous carbon electrodes possessed air/oxygen in the micropores, and the increased system pressure boosts the gases solubility in saline solution and carries them out of the cell in the effluent. Upon applying a potential difference to the electrodes, capacitive-based ion adsorption occurs in competition with faradaic reactions that consume oxygen. Through the addition of backpressure, the rate of degradation decreases, allowing the cell to maintain its salt adsorption capacity (SAC) longer. The removal of oxygen from ...
Enhancement Of Instruction Pamphlet Insertion Machine, 2018 The University of Akron
Enhancement Of Instruction Pamphlet Insertion Machine, Zachary Skraba, Colton Rentsch, Brad Ruhaak, Abdulwahab Almuhwish, Faris Almulhim
Honors Research Projects
For this project, we were tasked with improving the current operation of a pamphlet insertion machine for Weaver Industries. Located in Cuyahoga Falls, Ohio, Weaver Industries is a company whose mission is to “maximize the independence and personal fulfillment of individuals with disabilities.” The main operation of the prototype is to assist the handicapped operator by automating the process for one of their products, a “Kong” dog toy. Currently, the workers manually insert each pamphlet into the cardboard packaging by hand. Over the past three years, there have been three separate design groups tasked with building and improving upon each ...
Ball Oscillating Bouncer, 2018 The University of Akron
Ball Oscillating Bouncer, Eric Blok, Daniel Altemese, Ryan Nowacki, Maram Qurban
Honors Research Projects
The purpose of this report is to document the need, objectives, marketing and engineering requirements, as well as validate the design of an autonomous control device capable of continuously bouncing a table tennis ball on a paddle. This includes the design of a self correcting system using lightweight materials, and as few sensors and components as possible to achieve a compact, portable design. To accomplish this, the system is designed to react to a ball falling from as short a distance as 10 centimeters above the paddle, meaning all sensor processing, control processing, and motor drives should be able to ...
Human Powered Vehicle Design Team: Speed Variable Steering Stabilizer, 2018 The University of Akron
Human Powered Vehicle Design Team: Speed Variable Steering Stabilizer, Eric Miller, Matt Kraml
Honors Research Projects
The Human Powered Vehicle Competition (HPVC) is held annually by ASME at a few locations. The University of Akron has competed in the ASME-East and ASME-West competitions over the past handful of years against universities from all over the world. Objectives of each team for the competition are three-fold: vehicle design, racing performance, and innovation. Our senior design project involved working on the innovation concept for ASME-East 2018 held at Penn State University during the weekend of 4/13. Speed variable steering was decided upon by the entire HPVC team early in the design process as the innovation choice for ...
Dynamic Mechanical Analysis Piezoelectric Design, 2018 The University of Akron
Dynamic Mechanical Analysis Piezoelectric Design, Letia Bass, Michaela N. Mccrae, Ethan W. Goodman, Joesph W. Mazur
Honors Research Projects
This project is a continuation into the design and implementation of a Dynamic Mechanical Analysis (DMA) device that will be used to conduct high frequency testing on tire tread compounds. The design requirements necessary were to design a device that will produce a target frequency of 10 kHz with a 0.05% strain, while being at room temperature. The 3-D model developed by the previous year’s students was improved upon and new parts were designed as well. The assemblies (most importantly the connector piece) were 3-D modeled using Creo Parametric and analyzed with COMSOL Multiphysics. A new design involving ...
An Experimental Study On Static And Dynamic Strain Sensitivity Of Smart Concrete Sensors Doped With Carbon Nanotubes For Shm Of Large Structures, Andrea Meoni, Antonella D'Alessandro, Austin Downey, Enrique García-Macías, Marco Rallini, A. Luigi Materazzi, Luigi Torre, Simon Laflamme, Rafael Castro-Triguero, Filippo Ubertini
Civil, Construction and Environmental Engineering Publications
The availability of new self-sensing cement-based strain sensors allows the development of dense sensor networks for Structural Health Monitoring (SHM) of reinforced concrete structures. These sensors are fabricated by doping cement-matrix materials with conductive fillers, such as Multi Walled Carbon Nanotubes (MWCNTs), and can be embedded into structural elements made of reinforced concrete prior to casting. The strain sensing principle is based on the multifunctional composites outputting a measurable change in their electrical properties when subjected to a deformation. Previous work by the authors was devoted to material fabrication, modeling and applications in SHM. In this paper, we investigate the ...