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Effects Of Hard-To-Soft Segment Ratios On The Synthesis And Physico-Mechanical Properties Of Polyurethane Films, Aaron C. Wilson 2020 University of Texas at Tyler

Effects Of Hard-To-Soft Segment Ratios On The Synthesis And Physico-Mechanical Properties Of Polyurethane Films, Aaron C. Wilson

Mechanical Engineering Theses

Blood-contacting cardiovascular stents often induce a secondary clotting event due to unrestricted enzymatic activities. The use of hemocompatible polyurethane coatings on these implantable devices is one of the most promising methods to reduce device rejection. In this study, four commercial polyurethane films of various thicknesses and compositions were evaluated for their anticoagulation properties. Results suggested that these films exhibited excellent thermal and physico-mechanical properties while capable of increasing contact time with blood plasma by over a thousand-fold as compared to a control surface. Due to the unknown structure and composition of these commercial films, polyurethane samples were synthesized from toluene ...


Design Of A 3d Printed Bioreactor For Bone Cancer Research, Brooklyn K. VanDerWolde, Katelyn Hillson 2020 South Dakota State University

Design Of A 3d Printed Bioreactor For Bone Cancer Research, Brooklyn K. Vanderwolde, Katelyn Hillson

The Journal of Undergraduate Research

Bone cancer is an aggressive disease and has peak occurrence during physiological stimulation of growth and aging. Astronauts who undergo long-term space missions also acquire an increased risk of bone tissue degeneration and cancer. Few in-vitro models currently exist capable of reproducing the complex microenvironment of bone tissue to support multicellular activity in a three-dimensional structure. This limits the ability to understand disease progression and develop suitable treatment strategies. Therefore, developing a bone tissue model and an associated bioreactor is critical to understand the risks associated with cancer progression and improve treatment and preventions related to those risks. The goal ...


Hemodynamic Effects On Aortic Development Due To Outflow Tract Banding, Humza Ismail 2020 Washington University in St. Louis

Hemodynamic Effects On Aortic Development Due To Outflow Tract Banding, Humza Ismail

Engineering and Applied Science Theses & Dissertations

Hemodynamic forces drive remodeling of the early cardiac system in embryonic development. Perturbations of normal cardiac blood flow can cause the formation of defects and malformations within the cardiac system. Specifically, changes in hemodynamics can cause the formation of different congenital heart defects. The formation of heart defects has been studied; however, vasculature specific defects caused by changes in blood flow patterns in the early cardiac system have not been studied to the same degree. In this thesis, the effects of hemodynamic changes on arterial development were studied. Outflow tract banding (OTB) was used to cause a local increase in ...


Golf Swing Trainer Using Wii Balance Board, Brooks M. Leftwich, Nicholas Hassler, Clark A. Hall, Sam Gates, Thomas B. Vickery, Alec Rinehart, Zakkary B A Compton, Ryan A. Singley 2020 University of Tennessee, Knoxville

Golf Swing Trainer Using Wii Balance Board, Brooks M. Leftwich, Nicholas Hassler, Clark A. Hall, Sam Gates, Thomas B. Vickery, Alec Rinehart, Zakkary B A Compton, Ryan A. Singley

Chancellor’s Honors Program Projects

No abstract provided.


A Linear Actuator/Spring Steel-Driven Glove For Assisting Individuals With Activities Of Daily Living, Daniel Chizhik 2020 University of Maine

A Linear Actuator/Spring Steel-Driven Glove For Assisting Individuals With Activities Of Daily Living, Daniel Chizhik

Electronic Theses and Dissertations

Over three million people in the U.S. suffer from forearm and hand disabilities. This can result from aging, neurological disorders (e.g., stroke), chronic disease (e.g., arthritis), and injuries. Injuries to hands comprise one-third of all work-related injuries worldwide. This can lead to difficulties with activities of daily living (ADL), where one needs to grasp, lift, and release objects in the household. There is a rise in demand for assistive orthoses and gloves that can allow many people to regain their grasping/releasing ability and, thereby, their independence. The main contribution of this thesis is developing an assistive ...


Biodiesel Production From Chicken Feather Meal And Its Performance Analysis On Diesel Engine, Venkateswarulu TC, Indira Mikkili, Krupanidhi Srirama, Nazneen Bobby Md., John Babu Dulla, Venkata Narayana Alugunulla, Vivekananda S, Abraham Peele, Bangaraiah P 2020 Department of Bio-Technology, VFSTR (Deemed to be University), Vadlamudi-522213

Biodiesel Production From Chicken Feather Meal And Its Performance Analysis On Diesel Engine, Venkateswarulu Tc, Indira Mikkili, Krupanidhi Srirama, Nazneen Bobby Md., John Babu Dulla, Venkata Narayana Alugunulla, Vivekananda S, Abraham Peele, Bangaraiah P

Karbala International Journal of Modern Science

Biodiesel has intrinsic lubricating properties due to the presence of long chain fatty acids, which significantly help to reduce engine wear and tear. Poultry waste as an alternative energy source could aid in reducing greenhouse gases. Biodiesel acknowledges environmental issues as it is less toxic than diesel and is biodegradable too. It is much safer to handle due to its high flash point and consequently, air quality improves dramatically. From the energy point of view, as a renewable source of energy, it helps in energy conservation and ensures regular availability for production of fuel. The chicken feather meal with moderate ...


Lower Stiffness Orthopaedic Implants For Hemiarthroplasty, Carolyn Berkmortel 2020 The University of Western Ontario

Lower Stiffness Orthopaedic Implants For Hemiarthroplasty, Carolyn Berkmortel

Electronic Thesis and Dissertation Repository

One of the main drawbacks of hemiarthroplasty is that it involves the articulation of a foreign material against the native cartilage, and hence the native cartilage experiences accelerated wear. It is hypothesized that lowering the stiffness of hemiarthroplasty implants will decrease contact pressure and increase contact area, thus decrease wear. Lowering the stiffness was done using finite element analysis to lower the stiffness of the implant materials, and then to change the internal structure of the implants to increase their compliance. Structural changes produced no noticeable or favourable results, whereas material produced improved results for stiffnesses below a Young’s ...


Enhancing The Conductivity Of Cell-Laden Alginate Microfibers With Aqueous Graphene For Neural Applications, Marilyn C. McNamara, Amir Ehsan Niaraki-Asli, Jingshuai Guo, Jasmin Okuzono, Reza Montazami, Nicole N. Hashemi 2020 Iowa State University

Enhancing The Conductivity Of Cell-Laden Alginate Microfibers With Aqueous Graphene For Neural Applications, Marilyn C. Mcnamara, Amir Ehsan Niaraki-Asli, Jingshuai Guo, Jasmin Okuzono, Reza Montazami, Nicole N. Hashemi

Mechanical Engineering Publications

Microfluidically manufacturing graphene-alginate microfibers create possibilities for encapsulating rat neural cells within conductive 3D tissue scaffolding to enable the creation of real-time 3D sensing arrays with high physiological relavancy. Cells are encapsulated using the biopolymer alginate, which is combined with graphene to create a cell-containing hydrogel with increased electrical conductivity. Resulting novel alginate-graphene microfibers showed a 2.5-fold increase over pure alginate microfibers, but did not show significant differences in size and porosity. Cells encapsulated within the microfibers survive for up to 8 days, and maintain ~20% live cells over that duration. The biocompatible aqueous graphene suspension used in this ...


Use Of Body Composition Imaging To Calculate 3-D Inertial Parameters For Inverse Dynamic Analysis Of Youth Pitching Arm Kinetics, Dalton James Jennings 2020 California Polytechnic State University, San Luis Obispo

Use Of Body Composition Imaging To Calculate 3-D Inertial Parameters For Inverse Dynamic Analysis Of Youth Pitching Arm Kinetics, Dalton James Jennings

Master's Theses and Project Reports

The objectives of this study were to 1) calculate participant-specific segment inertial parameters using dual energy X-ray absorptiometry (DXA) data (referred to as full DXA-driven parameters) and compare the pitching arm kinetic predictions using full DXA-driven inverse dynamics vs scaled, DXA mass-driven (using DXA masses but scaled centers of mass and radii of gyration), and DXA scaled inverse dynamics(ID) (using the full DXA-driven inertial parameters averaged across all participants), 2) examine associations between full DXA-driven kinetics and body mass index (BMI) and 3) examine associations between full DXA-driven kinetics and segment mass index (SMI). Eighteen 10- to 11- year-olds ...


Adaptable Clean Energy Laboratory, Joao Marcelo Rocha Belmonte, Marc D. Compere 2020 Embry-Riddle Aeronautical University

Adaptable Clean Energy Laboratory, Joao Marcelo Rocha Belmonte, Marc D. Compere

Sustainability Conference

The Adaptable Clean Energy (ACE) Lab is a real-world, long term, test platform that will guide the courses of the Energy Systems track. The lab will provide realistic electrical and HVAC loads that mimic a solar powered office. The lab is a 20’ high cube shipping container modified with a door, windows, lights computers, air conditioner and appliances. The lab is Net-Zero and powered entirely from the sun. Two insulation test sections expose the exterior walls for research access to real external heat loads in a real building


Heart Valve Isogeometric Sequentially-Coupled Fsi Analysis With The Space–Time Topology Change Method, Takuya Terahara, Kenji Takizawa, Tayfun E. Tezduyar, Yuri Bazilevs, Ming-Chen Hsu 2020 Waseda University

Heart Valve Isogeometric Sequentially-Coupled Fsi Analysis With The Space–Time Topology Change Method, Takuya Terahara, Kenji Takizawa, Tayfun E. Tezduyar, Yuri Bazilevs, Ming-Chen Hsu

Mechanical Engineering Publications

Heart valve fluid–structure interaction (FSI) analysis is one of the computationally challenging cases in cardiovascular fluid mechanics. The challenges include unsteady flow through a complex geometry, solid surfaces with large motion, and contact between the valve leaflets. We introduce here an isogeometric sequentially-coupled FSI (SCFSI) method that can address the challenges with an outcome of high-fidelity flow solutions. The SCFSI analysis enables dealing with the fluid and structure parts individually at different steps of the solutions sequence, and also enables using different methods or different mesh resolution levels at different steps. In the isogeometric SCFSI analysis here, the first ...


Enhancement Of The Syncardia Total Artificial Heart For Pediatric Use, Margaret Clark, Madison Marks 2020 The University of Akron

Enhancement Of The Syncardia Total Artificial Heart For Pediatric Use, Margaret Clark, Madison Marks

Williams Honors College, Honors Research Projects

Pediatric patients with disorders and diseases of the heart have limited options with regards to implantable devices. Many of these implants are ventricular assist devices, which is not always suitable for a patient. Total artificial hearts (TAHs) have supported many adult patients until transplantation, and we believe that they could do the same for pediatric patients. SynCardia has the only Food and Drug Administration (FDA) approved TAH devices. Since SynCardia is the only company with FDA approved TAHs, we decided to modify the design of the SynCardia TAH for use in pediatric patients without compromising the function of the current ...


Medical Device For Loading Of Knee At Differing Angles, Alex Dragota 2020 The University of Akron

Medical Device For Loading Of Knee At Differing Angles, Alex Dragota

Williams Honors College, Honors Research Projects

Abstract

This was a design report for a device that would be used in patellar instability research. The device would be used inside an MRI machine and allow the patient to adjust the angle of their knee to the desired position.

Methods: Solidworks was used in the design process to model and to simulate the strength of the components used. The Solidworks simulation software allowed for a better understanding of the strength of individual components and the strength of the full device. Complexity of operating the device while inside an MRI machine were taken into account by using animations of ...


Recovery Of Encapsulated Adult Neural Progenitor Cells From Microfluidic-Spun Hydrogel Fibers Enhances Proliferation And Neuronal Differentiation, Bhavika B. Patel, Marilyn C. McNamara, Laura S. Pesquera-Colom, Emily M. Kozik, Jasmin Okuzonu, Nicole N. Hashemi, Donald S. Sakaguchi 2020 Iowa State University

Recovery Of Encapsulated Adult Neural Progenitor Cells From Microfluidic-Spun Hydrogel Fibers Enhances Proliferation And Neuronal Differentiation, Bhavika B. Patel, Marilyn C. Mcnamara, Laura S. Pesquera-Colom, Emily M. Kozik, Jasmin Okuzonu, Nicole N. Hashemi, Donald S. Sakaguchi

Genetics, Development and Cell Biology Publications

Because of the limitations imposed by traditional two-dimensional (2D) cultures, biomaterials have become a major focus in neural and tissue engineering to study cell behavior in vitro. 2D systems fail to account for interactions between cells and the surrounding environment; these cell–matrix interactions are important to guide cell differentiation and influence cell behavior such as adhesion and migration. Biomaterials provide a unique approach to help mimic the native microenvironment in vivo. In this study, a novel microfluidic technique is used to encapsulate adult rat hippocampal stem/progenitor cells (AHPCs) within alginate-based fibrous hydrogels. To our knowledge, this is the ...


Atv Dynamics And Pediatric Rider Safety, James T. Auxier II 2020 University of Kentucky

Atv Dynamics And Pediatric Rider Safety, James T. Auxier Ii

Theses and Dissertations--Biomedical Engineering

It has been observed through numerous academic and governmental agency studies that pediatric all-terrain vehicle ridership carries significant risk of injury and death. While no doubt valuable to safety, the post-hoc approach employed in these studies does little to explain the why and how behind the risk factors. Furthermore, there has been no prolonged, widespread, organized, and concerted effort to reconstruct and catalog the details and causes of the large (20,000+) number of ATV-related injuries that occur each year as has been done for road-based motor vehicle accidents. This dissertation takes the opposite approach from a meta-analysis and instead ...


Electrophoresis In Heterogeneous Hydrogels And Applications In Surface Patterning, Ning Ge 2020 University of Kentucky

Electrophoresis In Heterogeneous Hydrogels And Applications In Surface Patterning, Ning Ge

Theses and Dissertations--Mechanical Engineering

The creation of chemical micropatterns on surfaces makes it possible to add unique chemical functionality to surfaces, modifying properties such as wettability, or even adding the ability to selectively bind other molecules. The creation of biochemical surface patterning in particular is useful in a variety of fields including tissue engineering and highthroughput drug screening. There are many existing surface patterning techniques which focus on precise control over the patterned geometry, even down to submicron scale features, but they do not allow local control over chemical concentration. So the results are high resolution patterns with binary concentration. There are also existing ...


Effects Of A Hip Orthosis On Lumbopelvic Coordination In Individuals With And Without Low Back Pain, Colin Drury 2020 University of Kentucky

Effects Of A Hip Orthosis On Lumbopelvic Coordination In Individuals With And Without Low Back Pain, Colin Drury

Theses and Dissertations--Biomedical Engineering

Individuals with low back pain (LBP) demonstrate an abnormal lumbopelvic coordination compared to back-healthy individuals. This abnormal coordination presents itself as a reduction in lumbar contribution and an increase in pelvic contribution to trunk motion. This study investigated the ability of a hip orthosis to correct such an abnormal lumbo-pelvic coordination by restricting pelvic rotation and, as a result, increasing lumbar contributions. The effects of the hip orthosis on the magnitude and timing characteristics of lumbopelvic coordination were investigated in 20 patients with LBP and 20 asymptomatic controls. The orthosis significantly increased lumbar contributions by 11%, 5.42%, 4.84 ...


Efficacy Of Hard Hats In Attenuating Head Accelerations: A Combined Experimental And Computational Investigation, Arthur Aloisio Alves Dos Santos 2020 University of North Florida

Efficacy Of Hard Hats In Attenuating Head Accelerations: A Combined Experimental And Computational Investigation, Arthur Aloisio Alves Dos Santos

UNF Graduate Theses and Dissertations

Struck-by accidents are a leading cause of traumatic brain injuries in the construction industry. While hard hats are the conventional means of industrial head protection, the current test standard to evaluate hard hat performance does not assess their ability to mitigate head accelerations from such impacts. To address this gap in knowledge, three investigations were pursued as part of this thesis. First, a variety of commercially available hard-hat designs – differentiated by shell design, number of suspension points, and suspension tightening system – were tested for their ability to attenuate accelerations during vertical impacts to the head. All hard-hats appreciably reduced head ...


Biomechanical Analysis Of Open-Skull High-Rate Traumatic Brain Injury Using Finite Element Mouse Brain Model, Lihong Lu 2019 The University of Western Ontario

Biomechanical Analysis Of Open-Skull High-Rate Traumatic Brain Injury Using Finite Element Mouse Brain Model, Lihong Lu

Electronic Thesis and Dissertation Repository

To better understand traumatic brain injury (TBI), it is necessary to correlate with injuries, which are observed from in vivo laboratory experiments, to brain mechanical responses, which can so far be best predicted by finite element (FE) models. Firstly, a previously validated FE model was improved to investigate the effect of repeated impacts and lateral movements on brain responses to ensure the accuracy and reproducibility of controlled cortical impact (CCI) across different labs. Then, a new FE mouse brain model with the detailed three-dimensional (3D), non-linear vasculature was developed to study how the vasculature affected brain response in CCI and ...


Cdse Quantum Dots Synthesis Laboratory Course For High School Students, Danlin Zuo, Gyuseok Kim, David Jones 2019 Singh Center for Nanotechnology

Cdse Quantum Dots Synthesis Laboratory Course For High School Students, Danlin Zuo, Gyuseok Kim, David Jones

Protocols and Reports

Cadmium selenide quantum dot is a fascinating subject for leading high school students to the quantum world. An 8-hour laboratory course for up to 12 high school students is proposed. The 8-hour course consist of two 4-hours sections. This laboratory course includes the quantum dot syntheses, absorption and emission characterization, and data analysis. The proposes process runs at relatively lower temperature which means safe and easy, and shows apparent experimental results.


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