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459 full-text articles. Page 1 of 17.

Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller 2017 Universite de Montpellier II

Estimation Of The Centre Of Mass From Motion Capture And Force Plate Recordings: A Study On The Elderly, Sebastien Cotton, Michele Vanoncini, Philippe Fraisse, Nacim Ramdani, Emel Demircan, Andrew P. Murray, Thierry Keller

Andrew P. Murray

The estimation of the centre of mass position in humans is usually based on biomechanical models developed from anthropometric tables. This method can potentially introduce errors in studies involving elderly people, since the ageing process is typically associated with a modification of the distribution of the body mass. In this paper, an alternative technique is proposed, and evaluated with an experimental study on 9 elderly volunteers. The technique is based on a virtual chain, identified from experimental data and locating the subject's centre of mass. Its configuration defines the location of the centre of mass, and is a function ...


Skin Strain Measurement To Predict Knee Joint Angles Through Nanocomposite Stain Gauges, Adin Martineau, James Tracy, Gavin Collins, Parker Rosquist, Dustin A. Bruening, Matt K. Seeley, David T. Fullwood, Anton E. Bowden 2017 Brigham Young University

Skin Strain Measurement To Predict Knee Joint Angles Through Nanocomposite Stain Gauges, Adin Martineau, James Tracy, Gavin Collins, Parker Rosquist, Dustin A. Bruening, Matt K. Seeley, David T. Fullwood, Anton E. Bowden

Biomedical Engineering Western Regional Conference

Explores the possibility of using high deflection nanocomposite strain gauges as knee joint angle sensor.


Characterization Of Essential Tremor In The Major Degrees Of Freedom Of The Upper Limb, Adam Pigg, David Standring, Steven Charles 2017 Brigham Young University - Provo

Characterization Of Essential Tremor In The Major Degrees Of Freedom Of The Upper Limb, Adam Pigg, David Standring, Steven Charles

Biomedical Engineering Western Regional Conference

No abstract provided.


Computational Characterization Of Blood Vessel Strain In Wire Myography, Sameer S. Nandikar, M Converse, K L. Monson 2017 University of Utah

Computational Characterization Of Blood Vessel Strain In Wire Myography, Sameer S. Nandikar, M Converse, K L. Monson

Biomedical Engineering Western Regional Conference

Blood vessels, and the mechanical forces that act on them, play a key role in both health and disease. As a consequence, the mechanical properties of vessels have been under study for over a century. A variety of approaches have been used to define vessel properties, including stretching of vessel rings to study circumferential behavior, a configuration commonly used in wire myography. The objective of the present study was to develop a finite element model to quantify strains throughout a vessel ring during such loading.


Using Optimization To Determine Tremor Propagation, Paul Curtis, Steven K. Charles 2017 Brigham Young University - Provo

Using Optimization To Determine Tremor Propagation, Paul Curtis, Steven K. Charles

Biomedical Engineering Western Regional Conference

: Essential Tremor (ET) is one of the most common movement disorders, with millions affected in the US. Currently there are two main treatment options: medication and deep brain stimulation (DBS). Available medications are only 50% effective, and in only 50% of patients, and many patients consider DBS too invasive. The purpose of our research is to determine the origin and propagation of tremor throughout the upper limb.


Rapid And Label-Free Detection Of Interferon Gamma Via An Electrochemical Aptasensor Comprising A Ternary Surface Monolayer On A Gold Interdigitated Electrode Array, Shaowei Ding, Curtis L. Mosher, Xian Y. Lee, Suprem R. Das, Allison A. Cargill, Xiaohui Tang, Bolin Chen, Eric S. McLamore, Carmen Gomes, Jesse M. Hostetter, Jonathan C. Claussen 2017 Iowa State University

Rapid And Label-Free Detection Of Interferon Gamma Via An Electrochemical Aptasensor Comprising A Ternary Surface Monolayer On A Gold Interdigitated Electrode Array, Shaowei Ding, Curtis L. Mosher, Xian Y. Lee, Suprem R. Das, Allison A. Cargill, Xiaohui Tang, Bolin Chen, Eric S. Mclamore, Carmen Gomes, Jesse M. Hostetter, Jonathan C. Claussen

Mechanical Engineering Publications

A label-free electrochemical impedance spectroscopy (EIS) aptasensor for rapid detection (<35 min) of interferon-gamma (IFN-γ) was fabricated by immobilizing a RNA aptamer capture probe (ACP), selective to IFN-γ, on a gold interdigitated electrode array (Au IDE). The ACP was modified with a thiol group at the 5′ terminal end and subsequently co-immobilized with 1,6-hexanedithiol (HDT) and 6-mercapto-1-hexanolphosphate (MCH) to the gold surface through thiol–gold interactions. This ACP/HDT-MCH ternary surface monolayer facilitates efficient hybridization with IFN-γ and displays high resistance to nonspecific adsorption of nontarget proteins [i.e., fetal bovine serum (FBS) and bovine serum albumin (BSA)]. The Au IDE functionalized with ACP/HDT-MCH was able to measure IFN-γ in actual FBS solution with a linear sensing range from 22.22 pM to 0.11 nM (1–5 ng/mL) and a detection limit of 11.56 pM. The ability to rapidly sense IFN-γ within this sensing range makes the developed electrochemical platform conducive toward in-field disease detection of a variety of diseases including paratuberculosis (i.e., Johne’s Disease). Furthermore, experimental results were numerically validated with an equivalent circuit model that elucidated the effects of the sensing process and the influence of the immobilized ternary monolayer on signal output. This is the first time that ternary surface monolayers have been used to selectively capture/detect IFN-γ on Au IDEs.


Skintronics: Wireless, Skin-Wearable Electronics For Monitoring Of Electrocardiogram, Matthew B. Piper, Woon-Hong Yeo, Yongkuk Lee 2017 Virginia Commonwealth University

Skintronics: Wireless, Skin-Wearable Electronics For Monitoring Of Electrocardiogram, Matthew B. Piper, Woon-Hong Yeo, Yongkuk Lee

Undergraduate Research Posters

The ECGs I micro-fabricate are designed to be flexible, stretchable and wireless circuits that can be applied to the skin directly. The device is encased in a conformal, silicon-like substrate, that allows the ECG to be attached with the electrodes. Each electrode has been previously measured and verified that it will be correctly placed for an accurate reading. Prototyping this ECG/electrode device allows the user to mount the prototype directly to the patient without having to attach and wire ten other electrodes. This prototype solves the issue that comes about when a doctor, nurse or emergency medical technician must ...


Lighted Ear Curette, Kaitlin Klotzle, Kelsey Ashmore, Crysta Yamamoto, Katrina Elfrink, Cynthia Stoller 2017 The University of Akron

Lighted Ear Curette, Kaitlin Klotzle, Kelsey Ashmore, Crysta Yamamoto, Katrina Elfrink, Cynthia Stoller

Honors Research Projects

The ear canal is a sensitive and small part of the human body that is prone to accumulate cerumen or lodge foreign bodies. In order to clean the ear canal or remove foreign bodies, three hands are required: one to brace the patient's head, one to maneuver the curette that is used to clean the ear, and one to hold a light source in order to make the small, dark area visible. Therefore, a design is needed that can allow a doctor to safely clean an ear with an instrument that only requires two hands. Furthermore, the design must ...


An Emg-Based Patient Monitoring System Using Zynq Soc Device, Farhad Fallahlalehzari 2016 University of Nevada, Las Vegas

An Emg-Based Patient Monitoring System Using Zynq Soc Device, Farhad Fallahlalehzari

UNLV Theses, Dissertations, Professional Papers, and Capstones

This thesis describes the design, development, and testing of an EMG-based patient monitoring system using the Zynq device. Zynq is a system on chip device designed by Xilinx which consists of an ARM dual cortex-A9 processor as well as an FPGA integrated into one chip. This work also analyzes the performance of image-processing algorithms on this system and compares that performance to more traditional PC-based systems. Image processing algorithms, such as Sobel edge detection, dilation and erosion, could be used in conjunction with a camera for the patient monitoring purposes. These algorithms often perform sub-optimally on processors because of their ...


The Effects Of Cryopreservation On Human Dental Pulp-Derived Mesenchymal Stem Cells, Allison Elaine Tomlin 2016 University of Nevada, Las Vegas

The Effects Of Cryopreservation On Human Dental Pulp-Derived Mesenchymal Stem Cells, Allison Elaine Tomlin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Many studies have demonstrated clinical applications for the use of dental pulp stem cells (DPSC) for the treatment of various conditions. This has driven medical and scientific interest in the collection, isolation and banking of DPSC tissues for research into these potential therapies. Few studies to date have evaluated the viability of DPSC following long-term cryopreservation. The purpose of this study is to evaluate the effects of cryopreservation on dental pulp-derived stem cells (DPSC) viability over a period of three years. Dental pulp-derived stem cells were isolated and cultured from thirty-one healthy teeth. DPSC isolates were assessed for doubling-time and ...


Design And Evaluation Of Pediatric Gait Rehabilitation Robots, Cale J. Stolle 2016 University of Nebraska-Lincoln

Design And Evaluation Of Pediatric Gait Rehabilitation Robots, Cale J. Stolle

Mechanical (and Materials) Engineering -- Dissertations, Theses, and Student Research

Gait therapy methodologies were studied and analyzed for their potential for pediatric patients. Using data from heel, metatarsal, and toe trajectories, a nominal gait trajectory was determined using Fourier transforms for each foot point. These average trajectories were used as a basis of evaluating each gait therapy mechanism. An existing gait therapy device (called ICARE) previously designed by researchers, including engineers at the University of Nebraska-Lincoln, was redesigned to accommodate pediatric patients. Unlike many existing designs, the pediatric ICARE did not over- or under-constrain the patient’s leg, allowing for repeated, comfortable, easily-adjusted gait motions. This design was assessed under ...


Flex-Ro: Design, Implementation, And Control Of Subassemblies For An Agricultural Robotic Platform, Jared Patrick Werner 2016 University of Nebraska - Lincoln

Flex-Ro: Design, Implementation, And Control Of Subassemblies For An Agricultural Robotic Platform, Jared Patrick Werner

Biological Systems Engineering--Dissertations, Theses, and Student Research

Automation technology in agriculture is growing, making agricultural robotics viable. Innovative field usable multi-purpose robotic platforms are needed for the successful progression of agricultural robotics. Furthermore, the field of agricultural robotics would benefit from a robotic platform design allowing for variable height, thus accommodating navigation throughout various crop growth stages. A variable height machine, Flex-Ro was developed to accommodate this feature. Multiple sub-assemblies were designed and implemented for Flex-Ro. An electronic control unit (ECU) enabled engine was used to power Flex-Ro. An embedded application program was developed to control engine speed using proprietary Controller Area Network (CAN) messages in conjunction ...


Development And Implementation Of High Fidelity Human Models For The Investigation Of Blast And Non-Penetrating Projectile Impact, Candice F. Cooper 2016 University of New Mexico

Development And Implementation Of High Fidelity Human Models For The Investigation Of Blast And Non-Penetrating Projectile Impact, Candice F. Cooper

Mechanical Engineering ETDs

Military operations abroad have highlighted the effects of several types of physical traumas including traumatic brain injury and behind armor blunt trauma. While previous approaches toward understanding and mitigating trauma caused by blast or blunt impact relied upon physical testing of animal subjects, post mortem human subjects, or human tissue surrogates, recent advances in computational capability have spurred a growing area of research in computational investigations into wound injury and its mitigation. The development of high-fidelity human torso and head-neck-torso models are presented here. These models are employed in blast and non-penetrating projectile impact simulations in order to demonstrate the ...


Fluid Dynamic Factors As A Cause And Effect Of Biofilm Formation Of Staphylococcus Aureus Biofilms, Erica Sherman 2016 University of Nebraska - Lincoln

Fluid Dynamic Factors As A Cause And Effect Of Biofilm Formation Of Staphylococcus Aureus Biofilms, Erica Sherman

Mechanical (and Materials) Engineering -- Dissertations, Theses, and Student Research

Staphylococcus aureus bacteria are able to form biofilms and distinctive tower structures that facilitate their ability to tolerate treatment and to spread within the human body. The formation of towers, which break off, get carried downstream and serve to initiate biofilms in other parts of the body are of particular interest here. It is known that flow conditions play a role in the development, dispersion and propagation of biofilms. The influence of flow on tower formation and what factors lead to tower formation is not at all understood The hypothesis being examined is that tower structures form within a specific ...


Movement And Distribution Of Bacteria Near Surfaces, Daniel A. Quinkert, Adib Ahmadzadegan, Arezoo M. Ardekani 2016 Purdue University

Movement And Distribution Of Bacteria Near Surfaces, Daniel A. Quinkert, Adib Ahmadzadegan, Arezoo M. Ardekani

The Summer Undergraduate Research Fellowship (SURF) Symposium

Bacteria are found everywhere in nature, including within human/animal bodies, biomedical devices, industrial equipment, oceans and lakes. They can be found in planktonic state within a bulk liquid phase or attached to surfaces with the potential to form biofilms. In this study we are interested in the movement and distribution of bacteria near surfaces. The concentrations and fluid interactions of bacteria were characterized at various distances from a surface. Psuedomonas putida F1 was observed in a suspension near a surface. Bacteria movements were visualized with an inverted microscope at 40x magnification. P. putida F1 exhibited greater density in close ...


Mechanical Reliability Of Implantable Polyimide-Based Magnetic Microactuators For Biofouling Removal, Christian G. Figueroa-Espada, Qi Yang, Hyowon Lee 2016 University of Puerto Rico, Mayaguez

Mechanical Reliability Of Implantable Polyimide-Based Magnetic Microactuators For Biofouling Removal, Christian G. Figueroa-Espada, Qi Yang, Hyowon Lee

The Summer Undergraduate Research Fellowship (SURF) Symposium

Hydrocephalus is a neurological disorder that typically requires a long-term implantation of a shunt system to manage its symptoms. These shunt systems are notorious for their extremely high failure rate. More than 40% of all implanted shunt systems fail within the first year of implantation. On average, 85% of all hydrocephalus patients with shunt systems undergo at least two shunt-revision surgeries within 10 years of implantation. A large portion of this high failure rate can be attributed to biofouling-related obstructions and infections. Previously, we developed flexible polyimide-based magnetic microactuators to remove obstructions formed on hydrocephalus shunts. To test the long-term ...


Microfluidic Platform For Impedance Characterization Of Endothelial Cells Under Fluid Shear Stress., Vanessa Velasco 2016 University of Louisville

Microfluidic Platform For Impedance Characterization Of Endothelial Cells Under Fluid Shear Stress., Vanessa Velasco

Electronic Theses and Dissertations

Endothelium dysfunction has been associated with many pathophysiological processes leading to cardiovascular diseases. Studying endothelium behavior is vital to understand the onset, prevention, and treatment of such diseases. Electrical impedance spectroscopy has been shown to provide a real-time in vitro evaluation of cell behavior including cell monolayer permeability. However, the majority of published work has been primarily with static cell culture models or macro-scale models that do not properly represent the physiological sizes, structures, and environmental conditions of human blood vessels. Within this dissertation, the design, fabrication, characterization, and application of a microfluidic impedance platform is presented for the in ...


Strain Energy Absorption Corresponds To Decreased Incidence Of Ventricular Fibrillation In A Commotio Cordis Model, Kayt E. Frisch, Mark S. Link, John Van Weelden 2016 Dordt College

Strain Energy Absorption Corresponds To Decreased Incidence Of Ventricular Fibrillation In A Commotio Cordis Model, Kayt E. Frisch, Mark S. Link, John Van Weelden

Faculty Work: Comprehensive List

A healthy teenage boy is playing high school baseball, when he is struck in the chest by the ball; minutes later, his heart is experiencing ventricular fibrillation (VF) and the only way to resuscitate him is to use a defibrillator. This phenomenon, is known as Commotio Cordis (CC), and occurs as many as 20 times each year in the United States. CC most frequently occurs in sports with small balls (e.g. baseball or lacrosse) and requires a specific set of circumstances–a projectile with a certain amount of energy that impacts directly over the left ventricle of the heart ...


Developing Predictive Models For Upper Extremity Post–Stroke Motion Quality Estimation Using Decision Trees And Bagging Forest, Sarvenaz Chaeibakhsh 2016 University of Tennessee, Knoxville

Developing Predictive Models For Upper Extremity Post–Stroke Motion Quality Estimation Using Decision Trees And Bagging Forest, Sarvenaz Chaeibakhsh

Masters Theses

Stroke is one of the leading causes of long–term disability. Approximately twothirds of stroke survivors require long-term rehabilitation, which suggests the importance of understanding the post-stroke recovery process during his activities of daily living. This problem is formulated as quantifying and estimating the poststroke movement quality in real world settings. To address this need, we have developed an approach that quantifies physical activities and can evaluate the performance quality. Wearable accelerometer and gyroscope are used to measure the upper extremity motions and to develop a mathematical framework to objectively relates sensors’ data to clinical performance indices. In this article ...


Non-Puncturing, No Slip Thv Leaflet Gripper, Brooks Kelly, Eric Nagaoka, Johnny Phane 2016 California Polytechnic State University, San Luis Obispo

Non-Puncturing, No Slip Thv Leaflet Gripper, Brooks Kelly, Eric Nagaoka, Johnny Phane

Mechanical Engineering

Confidential


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