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The Positive Role Of Curcumin-Loaded Salmon Nanoliposomes On The Culture Of Primary Cortical Neurons, Mahmoud Hasan, Shahrzad Latifi, Cyril J.F. Kahn, Ali Tamayol, Rouhollah Habibey, Elodie Passeri, Michel Linder, Elmira Arab-Tehrany 2018 Université de Lorraine

The Positive Role Of Curcumin-Loaded Salmon Nanoliposomes On The Culture Of Primary Cortical Neurons, Mahmoud Hasan, Shahrzad Latifi, Cyril J.F. Kahn, Ali Tamayol, Rouhollah Habibey, Elodie Passeri, Michel Linder, Elmira Arab-Tehrany

Mechanical & Materials Engineering Faculty Publications

Curcumin (diferuloylmethane) is a natural bioactive compound with many health-promoting benefits. However, its poor water solubility and bioavailability has limited curcumin’s biomedical application. In the present study, we encapsulated curcumin into liposomes, formed from natural sources (salmon lecithin), and characterized its encapsulation efficiency and release profile. The proposed natural carriers increased the solubility and the bioavailability of curcumin. In addition, various physico-chemical properties of the developed soft nanocarriers with and without curcumin were studied. Nanoliposome-encapsulated curcumin increased the viability and network formation in the culture of primary cortical neurons and decreased the rate of apoptosis.


Numerical Simulation Of Energy Localization In Dynamic Materials, Arkadi Berezovski, Mihhail Berezovski 2018 Tallinn University of Technology

Numerical Simulation Of Energy Localization In Dynamic Materials, Arkadi Berezovski, Mihhail Berezovski

Publications

Dynamic materials are artificially constructed in such a way that they may vary their characteristic properties in space or in time, or both, by an appropriate arrangement or control. These controlled changes in time can be provided by the application of an external (non-mechanical) field, or through a phase transition. In principle, all materials change their properties with time, but very slowly and smoothly. Changes in properties of dynamic materials should be realized in a short or quasi-nil time lapse and over a sufficiently large material region. Wave propagation is a characteristic feature for dynamic materials because it is also ...


Screening Algorithm Based On The Color Halftone Fluorescent Printing And Its Application In Packaging Design, Hu Yaojian, Liu Juan, Wang Ruojing, Zhong Yunfei 2018 Hunan University of Technology

Screening Algorithm Based On The Color Halftone Fluorescent Printing And Its Application In Packaging Design, Hu Yaojian, Liu Juan, Wang Ruojing, Zhong Yunfei

Journal of Applied Packaging Research

Abstract:This paper analyzed the characteristics of colorless fluorescent ink and the existing color separation theory, so that colored additive method should be used in printing color pattern with colorless fluorescent ink as well as three-color screening separation type (red, green and blue). Considering the exhibition of the tone, this paper selected dot parallel screening method. At the same time, through comparing the properties of different dots, this paper adopted a special method of AM screening, using regular triangle as the basic dot model to a threshold matrix of AM screening. Finally, designing a screening algorithm which best suit the ...


Variable Input Observer For State Estimation Of High-Rate Dynamics, Jonathan Hong, Liang Cao, Simon Laflamme, Jacob Dodson 2018 Iowa State University

Variable Input Observer For State Estimation Of High-Rate Dynamics, Jonathan Hong, Liang Cao, Simon Laflamme, Jacob Dodson

Simon Laflamme

High-rate systems operating in the 10 μs to 10 ms timescale are likely to experience damaging effects due to rapid environmental changes (e.g., turbulence, ballistic impact). Some of these systems could benefit from real-time state estimation to enable their full potential. Examples of such systems include blast mitigation strategies, automotive airbag technologies, and hypersonic vehicles. Particular challenges in high-rate state estimation include: 1) complex time varying nonlinearities of system (e.g. noise, uncertainty, and disturbance); 2) rapid environmental changes; 3) requirement of high convergence rate. Here, we propose using a Variable Input Observer (VIO) concept to vary the input ...


Robust Variable Input Observer For Structural Health Monitoring Of Systems Experiencing Harsh Extreme Environments, Jonathan Hong, Liang Cao, Simon Laflamme, Jacob Dodson 2018 Iowa State University

Robust Variable Input Observer For Structural Health Monitoring Of Systems Experiencing Harsh Extreme Environments, Jonathan Hong, Liang Cao, Simon Laflamme, Jacob Dodson

Simon Laflamme

Systems experiencing events in the order of 10μs-10ms timescales, for instance highrate dynamics or harsh extreme environments, may encounter rapid damaging effects. If the structural health of such systems could be accurately estimated in a timely manner, preventative measures could be employed to minimize adverse effects. Previously, a Variable Input Observer (VIO) coupled with a neuro-observer was proposed by the authors as a potential solution in monitoring their structural health. The objective of the VIO is to provide state estimation based on an optimal input space allowed to vary as a function of time. The VIO incorporates the use of ...


Microsecond State Monitoring Of Nonlinear Time-Varying Dynamic Systems, Jacob Dodson, Bryan Joyce, Simon Laflamme, Janet Wolfson 2018 Air Force Research Laboratory

Microsecond State Monitoring Of Nonlinear Time-Varying Dynamic Systems, Jacob Dodson, Bryan Joyce, Simon Laflamme, Janet Wolfson

Simon Laflamme

Reliable operation of next generation high-speed complex structures (e.g. hypersonic air vehicles, space structures, and weapons) relies on the development of microsecond structural health monitoring (μSHM) systems. High amplitude impacts may damage or alter the structure, and therefore change the underlying system configuration and the dynamic response of these systems. While state-of-the-art structural health monitoring (SHM) systems can measure structures which change on the order of seconds to minutes, there are no real-time methods for detection and characterization of damage in the microsecond timescales.

This paper presents preliminary analysis addressing the need for microsecond detection of state and parameter ...


Adaptive Structural Control Using Dynamic Hyperspace, Simon Laflamme 2018 Iowa State University

Adaptive Structural Control Using Dynamic Hyperspace, Simon Laflamme

Simon Laflamme

The design of closed-loop structural control systems necessitates a certain level of robustness to cope with system uncertainties. Neurocontrollers, a type of adaptive control system, have been proposed to cope with those uncertainties. However, the performance of neural networks can be substantially influenced by the choice of the input space, or the hyperspace in which the representation lies. For instance, input selection may influence computation time, adaptation speed, effects of the curse of dimensionality, understanding of the representation, and model complexity. Input space selection is often overlooked in literature, and inputs are traditionally determined offline for an optimized performance of ...


Eigenstrain As A Mechanical Set-Point Of Cells, Shengmao Lin, Marsha C. Lampi, Cynthia A. Reinhart-King, Gary C.P. Tsui, Jian Wang, Carl A. Nelson, Linxia Gu 2018 University of Nebraska-Lincoln

Eigenstrain As A Mechanical Set-Point Of Cells, Shengmao Lin, Marsha C. Lampi, Cynthia A. Reinhart-King, Gary C.P. Tsui, Jian Wang, Carl A. Nelson, Linxia Gu

Mechanical & Materials Engineering Faculty Publications

Cell contraction regulates how cells sense their mechanical environment. We sought to identify the set-point of cell contraction, also referred to as tensional homeostasis. In this work, bovine aortic endothelial cells (BAECs), cultured on substrates with different stiffness, were characterized using traction force microscopy (TFM). Numerical models were developed to provide insights into the mechanics of cell–substrate interactions. Cell contraction was modeled as eigenstrain which could induce isometric cell contraction without external forces. The predicted traction stresses matched well with TFM measurements. Furthermore, our numerical model provided cell stress and displacement maps for inspecting the fundamental regulating mechanism of ...


Ureteral Tunnel Length Versus Ureteral Orifice Configuration In The Determination Of Ureterovesical Junction Competence: A Computer Simulation Model, Carlos A. Villanueva, J. Tong, Carl A. Nelson, Linxia Gu 2018 University of Nebraska Medical Center

Ureteral Tunnel Length Versus Ureteral Orifice Configuration In The Determination Of Ureterovesical Junction Competence: A Computer Simulation Model, Carlos A. Villanueva, J. Tong, Carl A. Nelson, Linxia Gu

Mechanical & Materials Engineering Faculty Publications

Introduction The long-held belief that a ureteral re-implant tunnel should be five times the diameter of the ureter, as proposed by Paquin in 1959, ignores the effect of the orifice on the occurrence of reflux. In 1969, Lyon proposed that the shape of the ureteral orifice (UO) is more important than the intravesical tunnel. However, both theories missed quantitative evidence from principles of physics. The goal of the current study was to test Lyon’s theory through numerical models (i.e. to quantify the sensitivity of ureterovesical junction (UVJ) competence to intravesical tunnel length and to the UO).

Materials and ...


Spot-R By Triax, Purdue ECT Team 2018 Construction Engineering & Management, Purdue University

Spot-R By Triax, Purdue Ect Team

ECT Fact Sheets

Triax’s Spot-r system was developed to tackle the construction industry’s unique safety and productivity challenges, stemming from a demonstrated lack of total jobsite visibility and automatically collected, easily accessible field data. Spot-r by Triax combines a proprietary mesh network with sensor technology to record and transmit previously unattainable workforce and equipment location, activity and safety data within a defined area – all in real-time.

The Spot-r network is installed around the site and operates in a 900 MHz network, with a subset using a cellular connection to forward Spot-r sensor data to Triax’s custom, cloud dashboard. In the ...


Mdp (Machine Drive Power) Intelligent Compaction Technology, Purdue ECT Team 2018 Construction Engineering & Management, Purdue University

Mdp (Machine Drive Power) Intelligent Compaction Technology, Purdue Ect Team

ECT Fact Sheets

Caterpillar developed MDP (Machine Drive Power) technology to fill this gap. Rather than an accelerometer and vibratory drum, it uses the principle of rolling resistance to provide indications of soil stiffness. This allows it to perform more reliably on cohesive and granular soils with less variability than accelerometer systems. It also means that the technology can be used on both vibratory and static drum compactors, which are often used on larger sites. While the technology is quite useful on its own, it is even better as a complementary technology to the existing accelerometer-based systems. Contractors who use vibratory soil compactors ...


Purdue’S Biowall, Purdue ECT Team 2018 Construction Engineering & Management, Purdue University

Purdue’S Biowall, Purdue Ect Team

ECT Fact Sheets

Mechanical ventilation, energy recovery ventilation, and infiltration (air that leaks into a building) are commonly used to introduce fresh air. These are all valid approaches, but a living plant-based filter is an innovative complement to these traditional technologies. A Biowall has the potential to improve indoor air quality while reducing the quantity of air needed for ventilation, creating the potential for energy savings. Figure 1 shows a Biowall prototype being evaluated in the ReNEWW House, a research home located near the Purdue University campus (http://www.renewwhouse.com/).


Effects Of Microstructure And Crystallography On Mechanical Properties Of Cold-Rolled Sae1078 Pearlitic Steel, Y. Liu, C. D. Yang, M. Liu, C. H. Wang, Y. C. Dai, X. Li, Alan M. Russell, C. X. Zhang, Z. H. Zhang, G. H. Cao 2018 Shanghai University

Effects Of Microstructure And Crystallography On Mechanical Properties Of Cold-Rolled Sae1078 Pearlitic Steel, Y. Liu, C. D. Yang, M. Liu, C. H. Wang, Y. C. Dai, X. Li, Alan M. Russell, C. X. Zhang, Z. H. Zhang, G. H. Cao

Materials Science and Engineering Publications

The evolution of the microstructure and crystallography in SAE1078 pearlitic steel sheets under different cold-rolling reductions of up to 90% were quantified using transmission electron microscopy (TEM), electron backscatter diffraction (EBSD), and X-ray diffraction (XRD). The mechanical properties were determined by tensile testing at room temperature. TEM analysis showed that the pearlite structure was obviously refined with the interlamellar spacing decreasing to about 57 nm at the rolling reduction of 90%. EBSD investigations indicated that the ferrite exhibited a {001}texture in the 90% cold-rolled pearlitic steel. The dislocations were mainly concentrated during cold rolling between the 10% and 70 ...


Atomic Force Microscopy-Based Investigation Of Plastic Deformation Mechanisms In Disordered Nanoparticle Packings, Joel Allen Lefever 2018 University of Pennsylvania

Atomic Force Microscopy-Based Investigation Of Plastic Deformation Mechanisms In Disordered Nanoparticle Packings, Joel Allen Lefever

Publicly Accessible Penn Dissertations

Understanding the plastic deformation mechanisms of disordered materials is a longstanding and complex problem in condensed matter physics and materials science. In particular, the elementary plastic rearrangement in a disordered material is believed to be the shear transformation zone, a localized cooperative motion of a handful of constituents. Although observed in mesoscale systems, the shear transformation zone has never been identified in an experiment at the nanoscale. In the present work, atomic force microscopy is used to probe the mechanical response of thin films of disordered nanoparticle packings that have been deposited by spin-coating and layer-by-layer deposition. Results demonstrate that ...


Defect Engineering: Novel Strengthening Mechanism For Low- Dimensional Zinc Oxide Nanostructures, Seyed Emad Rezaei 2018 Wright State University

Defect Engineering: Novel Strengthening Mechanism For Low- Dimensional Zinc Oxide Nanostructures, Seyed Emad Rezaei

Browse all Theses and Dissertations

The advent of nanomaterials has opened a new avenue for designing and fabricating materials with unique properties, e.g., superior mechanical properties. Based on a common notion, the perfect structures are assumed to exhibit better mechanical properties, such as higher yield strength and Young's modulus. Therefore, researchers have devoted an extensive amount of time to decrease defect concentration by fabricating materials with the micro/nanoscale, e.g., nanowires (NWs) and nanobelts (NBs), to enhance the mechanical characteristics of the system. However, defects are a part of the fabrication process and precise control over synthesizing procedure is needed to eliminate ...


Consuming Digital Debris In The Plasticene, Stephen R. Parks 2018 Virginia Commonwealth University

Consuming Digital Debris In The Plasticene, Stephen R. Parks

Theses and Dissertations

Claims of customization and control by socio-technical industries are altering the role of consumer and producer. These narratives are often misleading attempts to engage consumers with new forms of technology. By addressing capitalist intent, material, and the reproduction limits of 3-D printed objects’, I observe the aspirational promise of becoming a producer of my own belongings through new networks of production. I am interested in gaining a better understanding of the data consumed that perpetuates hyper-consumptive tendencies for new technological apparatuses. My role as a designer focuses on the resolution of not only the surface of the object through 3-D ...


Grain-Boundary Kinetics And Nonequilibrium Grain-Boundary Structure, Jian Han 2018 University of Pennsylvania

Grain-Boundary Kinetics And Nonequilibrium Grain-Boundary Structure, Jian Han

Publicly Accessible Penn Dissertations

Microstructure of polycrystalline materials can be described as grain boundary (GB) networks; hence, GBs play major role in a wide-range of polycrystal properties. Control over GB kinetics provides effective means to tailor polycrystal properties through material processing. Understanding and prediction of GB kinetic behavior are always central problems in materials science. In this thesis, these are realized based on a mechanistic model. The mechanistic model describes a GB as intrinsic GB structure decorated by extrinsic defects. GB kinetics is described by the transition among all the stable/metastable intrinsic GB structures and the kinetics of GB defects. A major type ...


Controlled Folding In Precisely Functionalized Polyethylenes: Designing Nanoscale Lamellar Structures For Ion Transport, Edward Boynton Trigg 2018 University of Pennsylvania

Controlled Folding In Precisely Functionalized Polyethylenes: Designing Nanoscale Lamellar Structures For Ion Transport, Edward Boynton Trigg

Publicly Accessible Penn Dissertations

There is great societal need for improved energy storage technology, in applications ranging from electric vehicles to grid storage to emergency power systems. New polymeric membranes with enhanced ion conductivities are needed in batteries and fuel cells to improve these technologies. Despite decades of research, these membrane materials are still not adequate for commercial use. The primary metric that requires improvement is ion or proton conductivity of the membrane under desirable operating conditions.

Modifying linear polyethylene by the addition of precisely periodic functional groups leads to a rich array of intriguing morphologies and properties. Depending on the functional group chemistry ...


A Fast Fourier Transform Approach To Dislocation-Based Polycrystal Plasticity, John Thomas Graham 2018 Iowa State University

A Fast Fourier Transform Approach To Dislocation-Based Polycrystal Plasticity, John Thomas Graham

Graduate Theses and Dissertations

Polycrystalline materials serve as a basis for much of our current technology and will undoubtedly continue to serve a similar role in the future. Their mechanical properties depend not only on intragranular interactions between various defects, including the distribution of sizes and orientations of the grains, but also interactions with the grain boundaries. Modeling the mechanical behavior of polycrystals has become a standard part of the multiscale treatment of deformation. Currently, polycrystalline simulations are done through crystal plasticity methods, which are often informed through elastically isotropic single-crystal dislocation dynamics studies. These single-crystal studies, however, miss out on crucial effects due ...


Computational Dynamics And Virtual Dragline Simulation For Extended Rope Service Life, Muhammad Wardeh 2018 Missouri University of Science and Technology

Computational Dynamics And Virtual Dragline Simulation For Extended Rope Service Life, Muhammad Wardeh

Doctoral Dissertations

"The dragline machinery is one of the largest equipment for stripping overburden materials in surface mining operations. Its effectiveness requires rigorous kinematic and dynamic analyses. Current dragline research studies are limited in computational dynamic modeling because they eliminate important structural components from the front-end assembly. Thus, the derived kinematic, dynamic and stress intensity models fail to capture the true response of the dragline under full operating cycle conditions. This research study advances a new and robust computational dynamic model of the dragline front-end assembly using Kane's method. The model is a 3-DOF dynamic model that describes the spatial kinematics ...


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