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Time Enough - Consequences Of Human Microchip Implantation, Elaine M. Ramesh 2016 University of New Hampshire

Time Enough - Consequences Of Human Microchip Implantation, Elaine M. Ramesh

RISK: Health, Safety & Environment

Dr. Ramesh argues that microchip implantation is both possible and, for some purposes, desirable and suggests that now is the time to consider strategies for preventing potentially grievous intrusion into personal privacy.


A Multi-Channel 3d-Printed Bioreactor For Evaluation Of Growth And Production In The Microalga Dunaliella Sp, Cristian A. Cox 2016 University of Maine

A Multi-Channel 3d-Printed Bioreactor For Evaluation Of Growth And Production In The Microalga Dunaliella Sp, Cristian A. Cox

Electronic Theses and Dissertations

We explored the capabilities of additive manufacturing using a photo-cured jetted material 3D printer to manufacture a milli-microfluidic device with direct application in microalgae Dunaliella sp growth and intracellular compounds biosynthesis tests. A continuous microbioreactor for microalgae culture was CAD designed and successfully built in 1 hour and 49 minutes using black photopolymer cured by UV and a support material. The microreactor was made up of 2 parts including the bioreactor itself and a microchannel network for culture media fluids and microalgae. Both parts were assembled to form a single unit. Additional optical and auxiliar components were added. An external ...


Analysis, Segmentation And Prediction Of Knee Cartilage Using Statistical Shape Models, Joseph Michael Johnson 2016 University of Tennessee - Knoxville

Analysis, Segmentation And Prediction Of Knee Cartilage Using Statistical Shape Models, Joseph Michael Johnson

Michael Johnson

Osteoarthritis (OA) of the knee is one of the leading causes of chronic disability (along with the hip). Due to rising healthcare costs associated with OA, it is important to fully understand the disease and how it progresses in the knee. One symptom of knee OA is the degeneration of cartilage in the articulating knee. The cartilage pad plays a major role in painting the biomechanical picture of the knee. This work attempts to quantify the cartilage thickness of healthy male and female knees using statistical shape models (SSMs) for a deep knee bend activity. Additionally, novel cartilage segmentation from ...


Analysis, Segmentation And Prediction Of Knee Cartilage Using Statistical Shape Models, Joseph Michael Johnson 2016 University of Tennessee - Knoxville

Analysis, Segmentation And Prediction Of Knee Cartilage Using Statistical Shape Models, Joseph Michael Johnson

Michael Johnson

Osteoarthritis (OA) of the knee is one of the leading causes of chronic disability (along with the hip). Due to rising healthcare costs associated with OA, it is important to fully understand the disease and how it progresses in the knee. One symptom of knee OA is the degeneration of cartilage in the articulating knee. The cartilage pad plays a major role in painting the biomechanical picture of the knee. This work attempts to quantify the cartilage thickness of healthy male and female knees using statistical shape models (SSMs) for a deep knee bend activity. Additionally, novel cartilage segmentation from ...


Synchronization Of Coupled Neurons Via Robust Feedback, Hector Puebla, Ricardo Aguilar-Lopez, Priti Kumar Roy 2016 Universidad Autonoma Metropolitana

Synchronization Of Coupled Neurons Via Robust Feedback, Hector Puebla, Ricardo Aguilar-Lopez, Priti Kumar Roy

Annual Symposium on Biomathematics and Ecology: Education and Research

No abstract provided.


Neural Representation Of Vocalizations In Noise In The Primary Auditory Cortex Of Marmoset Monkeys, Ruiye Ni 2016 Washington University in St. Louis

Neural Representation Of Vocalizations In Noise In The Primary Auditory Cortex Of Marmoset Monkeys, Ruiye Ni

Engineering and Applied Science Theses & Dissertations

Robust auditory perception plays a pivotal function in processing behaviorally relevant sounds, particularly when there are auditory distractions from the environment. The neuronal coding enabling this ability, however, is still not well understood. In this study we recorded single-unit activity from the primary auditory cortex of alert common marmoset monkeys (Callithrix jacchus) while delivering conspecific vocalizations degraded by two different background noises: broadband white noise (WGN) and vocalization babble (Babble).

Noise effects on single-unit neural representation of target vocalizations were quantified by measuring the response similarity elicited by natural vocalizations as a function of signal-to-noise ratio (SNR). Four consistent response ...


Haptic Foot Feedback For Kicking Training In Virtual Reality, Hank Huang, Hong Tan 2016 Purdue University

Haptic Foot Feedback For Kicking Training In Virtual Reality, Hank Huang, Hong Tan

The Summer Undergraduate Research Fellowship (SURF) Symposium

As means to further supplement athletic performances increases, virtual reality is becoming helpful to sports in terms of cognitive training such as reaction, mentality, and game strategies. With the aid of haptic feedback, interaction with virtual objects increases by another dimension, in addition to the presence of visual and auditory feedback. This research presents an integrated system of a virtual reality environment, motion tracking system, and a haptic unit designed for the dorsal foot. The prototype simulates a scenario of virtual kicking and returns haptic response upon collision between the user’s foot and virtual object. The overall system was ...


Mechanical Reliability Of Implantable Polyimide-Based Magnetic Microactuators For Biofouling Removal, Christian G. Figueroa-Espada, Qi Yang, Hyowon Lee 2016 University of Puerto Rico, Mayaguez

Mechanical Reliability Of Implantable Polyimide-Based Magnetic Microactuators For Biofouling Removal, Christian G. Figueroa-Espada, Qi Yang, Hyowon Lee

The Summer Undergraduate Research Fellowship (SURF) Symposium

Hydrocephalus is a neurological disorder that typically requires a long-term implantation of a shunt system to manage its symptoms. These shunt systems are notorious for their extremely high failure rate. More than 40% of all implanted shunt systems fail within the first year of implantation. On average, 85% of all hydrocephalus patients with shunt systems undergo at least two shunt-revision surgeries within 10 years of implantation. A large portion of this high failure rate can be attributed to biofouling-related obstructions and infections. Previously, we developed flexible polyimide-based magnetic microactuators to remove obstructions formed on hydrocephalus shunts. To test the long-term ...


A Novel Particle Filtering Method For Estimation Of Pulse Pressure Variation During Spontaneous Breathing, Sunghan Kim, Fouzia Noor, Mateo Aboy, James McNames 2016 East Carolina University

A Novel Particle Filtering Method For Estimation Of Pulse Pressure Variation During Spontaneous Breathing, Sunghan Kim, Fouzia Noor, Mateo Aboy, James Mcnames

Electrical and Computer Engineering Faculty Publications and Presentations

Background: We describe the first automatic algorithm designed to estimate the pulse pressure variation ([Formula: see text]) from arterial blood pressure (ABP) signals under spontaneous breathing conditions. While currently there are a few publicly available algorithms to automatically estimate [Formula: see text] accurately and reliably in mechanically ventilated subjects, at the moment there is no automatic algorithm for estimating [Formula: see text] on spontaneously breathing subjects. The algorithm utilizes our recently developed sequential Monte Carlo method (SMCM), which is called a maximum a-posteriori adaptive marginalized particle filter (MAM-PF). We report the performance assessment results of the proposed algorithm on real ...


The Design And Validation Of A Wireless Bat-Mounted Sonar Recording System, Jeremy Joseph Langford 2016 University of Tennessee, Knoxville

The Design And Validation Of A Wireless Bat-Mounted Sonar Recording System, Jeremy Joseph Langford

Masters Theses

Scientists studying the behavior of bats monitor their echolocation calls, as their calls are important for navigation and feeding, but scientist are typically restricted to ground-based recording. Recording bat calls used for echolocation from the back of the bat as opposed to the ground offers the opportunity to study bat echolocation from a vantage otherwise only offered to the bats themselves. However, designing a bat mounted in-flight audio recording system, (bat-tag), capable of recording the ultra-sound used in bat echolocation presents a unique set of challenges. Chiefly, the bat-tag must be sufficiently light weight as to not overburden the bat ...


Sonochemical Synthesis Of Zinc Oxide Nanostructures For Sensing And Energy Harvesting, Phani Kiran Vabbina 2016 Department of Electrical and Computer Engineering, Florida International University

Sonochemical Synthesis Of Zinc Oxide Nanostructures For Sensing And Energy Harvesting, Phani Kiran Vabbina

FIU Electronic Theses and Dissertations

Semiconductor nanostructures have attracted considerable research interest due to their unique physical and chemical properties at nanoscale which open new frontiers for applications in electronics and sensing. Zinc oxide nanostructures with a wide range of applications, especially in optoelectronic devices and bio sensing, have been the focus of research over the past few decades. However ZnO nanostructures have failed to penetrate the market as they were expected to, a few years ago. The two main reasons widely recognized as bottleneck for ZnO nanostructures are (1) Synthesis technique which is fast, economical, and environmentally benign which would allow the growth on ...


Microbubble Generation By Piezoelectric Transducers For Biomedical Studies, Mohammed Alkhazal 2016 Old Dominion University

Microbubble Generation By Piezoelectric Transducers For Biomedical Studies, Mohammed Alkhazal

Electrical & Computer Engineering Theses & Disssertations

Bubbles induced by blast waves or shocks are speculated as the major cause of damage in biological cells in mild traumatic brain injuries (TBI). Microbubble collapse was found to induce noticeable cell detachment from the cell substrate, changes in focal adhesion, and biomechanics. To better understand the bubble mechanism, a system needs to be constructed which allows clear differentiation on the impact of bubbles from that of shocks. Such a generator needs to be low profile in order to place under a microscope. A piezoelectric transducer system was designed to meet the need. The system uses either a flat or ...


Automated Microscopy Platform For High-Throughput Analysis Of Cellular Characteristics, Hussam Ibrahim 2016 Augustana College - Rock Island

Automated Microscopy Platform For High-Throughput Analysis Of Cellular Characteristics, Hussam Ibrahim

Physics: Student Scholarship & Creative Works

Existing microscopy platforms allow analysis post-hoc, but not in real time. This is an issue in the world of Bioengineering because you are limited to performing further analysis on specimen. The aim of my research was to design a sophisticated system whereby information can be exchanged between the software which acquires images and software that analyzes the images immediately after acquisition. In this system, images would be acquired by the microscope and analyzed by customized scripts (MATLAB, Mathworks) in real time. Specifically, MATLAB would wait for new images to be saved on the hard drive, import these images, and perform ...


A Stroke Therapy Brace Design, Evan Kirkbride 2016 California Polytechnic State University, San Luis Obispo

A Stroke Therapy Brace Design, Evan Kirkbride

Electrical Engineering

Victims of stroke often have difficulty with rehabilitation. With limited movement on their affected arm, patients often do not want to move much for physical therapy. In this project, we design a robotic brace that helps stroke patients move their arm more effectively in a reaching or pulling motion. By giving patients more movement in their affected arm than they would have otherwise, patients gain more from rehabilitation. The brace also adapts to the patient’s needs, providing more inclination or resistance as needed for their physical therapy. This kind of therapy engages patients rather than relying on their likely ...


Hall Effect Modeling In Fem Simulators And Comparison To Experimental Results In Silicon And Printed Sensors, Leonardo A. Frem 2016 California Polytechnic State University, San Luis Obispo

Hall Effect Modeling In Fem Simulators And Comparison To Experimental Results In Silicon And Printed Sensors, Leonardo A. Frem

Master's Theses and Project Reports

Finite element method simulation models for thin-film semiconductor-based Hall sensors were developed using secondary data in order to understand their behavior under strong magnetic fields. Given a device geometry and charge carrier density and mobility, the models accurately calculated sensor resistance, Hall voltage under a normally-incident constant magnetic field, and expected offset from a population of Hall devices. The model was successfully matched against data from integrated chip Hall sensors from St. Jude Medical. Additionally, the feasibility of creating Hall effect devices with common carbon ink was explored experimentally. The material properties obtained from testing these ink-based devices through the ...


Simulations Of A Variable Friction Device For Multihazard Mitigation, Liang Cao, Simon Laflamme, Douglas Taylor, James Ricles 2016 Iowa State University

Simulations Of A Variable Friction Device For Multihazard Mitigation, Liang Cao, Simon Laflamme, Douglas Taylor, James Ricles

Civil, Construction and Environmental Engineering Publications

This paper investigates the performance of a novel semiactive damping device at mitigating nonsimultaneous multihazard loads. The device, termed modified friction device (MFD), has been previously proposed by the authors. It consists of a variable friction system based on automotive drum brake technology. The device has been demonstrated in a laboratory environment, and its dynamic behavior has been modeled. This model is used to conduct numerical simulations on two representative structures, one short building located in Japan and the other tall building located in Boston, MA. Simulated hazards include wind, blast, and seismic loads. Various control cases are considered, including ...


Improving Radiation Therapy Through Motion Tracking, Hanlin Wan 2016 Washington University in St. Louis

Improving Radiation Therapy Through Motion Tracking, Hanlin Wan

Engineering and Applied Science Theses & Dissertations

Radiation therapy is a widely-used cancer treatment method in which lethal doses of ionizing radiation are delivered to cancerous cells. Given the high dose requirements and the risk of associated complications, it is essential that radiation be targeted to cancerous cells while minimizing the dose to surrounding tissue. While current technology allows for accurate targeting of radiation dose, there is one major hurdle: Respiratory motion causes movement of up to a few centimeters of tumors in the abdomen and thorax, rendering even the most accurate radiation delivery machine highly inaccurate. Imaging devices integrated with the treatment machines allow us to ...


Translational Photoacoustic Tomography, Yong Zhou 2016 Washington University in St. Louis

Translational Photoacoustic Tomography, Yong Zhou

Engineering and Applied Science Theses & Dissertations

Combining optical excitation and ultrasonic detection, photoacoustic tomography (PAT) offers deep imaging with high resolution. With optical excitation, PAT maintains the high contrast of optical imaging. Because of the low scattering of ultrasonic waves in tissue, PAT achieves high spatial resolution at depths. Several advantages make PAT suitable for clinical application, including its scalable penetration and resolution, high optical absorption contrast, fast imaging speed, and ability to perform spectral decomposition. Based on different image reconstruction mechanisms, PAT can be further divided into two embodiments: raster-scanning-based photoacoustic microscopy (PAM) and reconstruction-algorism-based photoacoustic computed tomography (PACT). This dissertation aims to advance the ...


Portable High Throughput Digital Microfluidics And On-Chip Bacteria Cultures, Yiyan Li 2016 University of Nevada, Las Vegas

Portable High Throughput Digital Microfluidics And On-Chip Bacteria Cultures, Yiyan Li

UNLV Theses, Dissertations, Professional Papers, and Capstones

An intelligent, portable, and high throughput digital microfluidic (DMF) system is developed. Chapter 1 introduces microfluidics and DMF systems. In Chapter 2, a low-cost and high resolution capacitive-to-digital converter integrated circuit is used for droplet position detection. A field-programmable gate array FPGA is used as the integrated logic hub of the system for highly reliable and efficient control of the circuit. In this chapter a fast-fabricating PCB (printed circuit board) substrate microfluidic system is proposed. Smaller actuation threshold voltages than those previously reported are obtained. Droplets (3 µL) are actuated using 200 V, 500 Hz DC pulses. Droplet positions can ...


Design And Implementation Of An Integrated Biosensor Platform For Lab-On-A-Chip Diabetic Care Systems, Khandaker Abdullah Al Mamun 2016 University of Tennessee - Knoxville

Design And Implementation Of An Integrated Biosensor Platform For Lab-On-A-Chip Diabetic Care Systems, Khandaker Abdullah Al Mamun

Doctoral Dissertations

Recent advances in semiconductor processing and microfabrication techniques allow the implementation of complex microstructures in a single platform or lab on chip. These devices require fewer samples, allow lightweight implementation, and offer high sensitivities. However, the use of these microstructures place stringent performance constraints on sensor readout architecture. In glucose sensing for diabetic patients, portable handheld devices are common, and have demonstrated significant performance improvement over the last decade. Fluctuations in glucose levels with patient physiological conditions are highly unpredictable and glucose monitors often require complex control algorithms along with dynamic physiological data. Recent research has focused on long term ...


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