Design Of An Affordable Rotating Drum Electrospinner For Classroom Education, 2020 South Dakota State University
Design Of An Affordable Rotating Drum Electrospinner For Classroom Education, Peder Solberg
The Journal of Undergraduate Research
Electrospinning is a technology used to generate small fibers down to nano-scale size. This method of fiber creation has been around for many years. However, in recent years electrospinning has found increased applications, especially in the area of tissue engineering due to its ability to create fibers with properties similar to the extracellular matrix in tissue. An electrospinning platform can illustrate concepts of engineering, electro-mechanical system design, manufacturing, and biomedical applications in one single package. Hence, it provides an excellent opportunity to integrate into secondary (middle and high school) and post-secondary (undergraduate) technology education.
Furthermore, just as integration of 3D ...
In-Situ Gold-Ceria Nanoparticles: Superior Optical Fluorescence Quenching Sensor For Dissolved Oxygen, 2020 Old Dominion University
In-Situ Gold-Ceria Nanoparticles: Superior Optical Fluorescence Quenching Sensor For Dissolved Oxygen, Nader Shehata, Ishac Kandas, Effat Samir
Electrical & Computer Engineering Faculty Publications
Cerium oxide (ceria) nanoparticles (NPs) have been proved to be an efficient optical fluorescent material through generating visible emission (~530 nm) under violet excitation. This feature allowed ceria NPs to be used as an optical sensor via the fluorescence quenching Technique. In this paper, the impact of in-situ embedded gold nanoparticles (Au NPs) inside ceria nanoparticles was studied. Then, gold–ceria NPs were used for sensing dissolved oxygen (DO) in aqueous media. It was observed that both fluorescence intensity and lifetime were changed due to increased concentration of DO. Added gold was found to enhance the sensitivity of ceria to ...
Eyecom: An Innovative Approach For Computer Interaction, 2020 Marshall University
Eyecom: An Innovative Approach For Computer Interaction, Anam Mazhar
Theses, Dissertations and Capstones
The world is innovating rapidly, and there is a need for continuous interaction with the technology. Sadly, there do not exist promising options for paralyzed people to interact with the machines i.e., laptops, smartphones, and tabs. A few commercial solutions such as Google Glasses are costly and cannot be afforded by every paralyzed person for such interaction. Towards this end, the thesis proposes a retina-controlled device called EYECOM. The proposed device is constructed from off-the-shelf cost-effective yet robust IoT devices (i.e., Arduino microcontrollers, Xbee wireless sensors, IR diodes, and accelerometer). The device can easily be mounted on to ...
Characterization Of Left Ventricular Volumes And Ejection Fraction In Patients With A Left Ventricular Assist Device, 2020 University of Central Florida
Characterization Of Left Ventricular Volumes And Ejection Fraction In Patients With A Left Ventricular Assist Device, Viswajith Siruvallur Vasudevan
Electronic Theses and Dissertations, 2020-
In the treatment of heart patients, as a bridge to recovery, the challenge currently in using a continuous-flow left ventricular assist device (LVAD), is to provide a method to monitor the recovery of the heart. This dissertation addresses the hypothesis that continuous monitoring of the ejection fraction of a patient implanted with an LVAD should be to examine the progress of the patient without the need for excessive in vivo measurements. Also, the ejection fraction can be used to provide a control mechanism for the pump depending on the requirements of each patient. In this dissertation, the left ventricle, in ...
Cdse Quantum Dots Synthesis Laboratory Course For High School Students, 2019 Singh Center for Nanotechnology
Cdse Quantum Dots Synthesis Laboratory Course For High School Students, Danlin Zuo, Gyuseok Kim, David Jones
Protocols and Reports
Cadmium selenide quantum dot is a fascinating subject for leading high school students to the quantum world. An 8-hour laboratory course for up to 12 high school students is proposed. The 8-hour course consist of two 4-hours sections. This laboratory course includes the quantum dot syntheses, absorption and emission characterization, and data analysis. The proposes process runs at relatively lower temperature which means safe and easy, and shows apparent experimental results.
Blood Glucose Predictor, 2019 California Polytechnic State University, San Luis Obispo
Blood Glucose Predictor, Jessica Patterson
For my senior project, I perform data analysis using statistical methods to determine body metrics that correlate with blood glucose levels. Working with Dr. Tina Smilkstein, I take repeat measurements from 6 different volunteers to establish trends in bodily metric data. The data taken includes weight, body fat, pulse rate, VO2, blood glucose, blood pressure, hours slept, and quality of sleep. Using these values, I use the program MiniTab to view results.
A few examples of correlations with blood glucose found in this project are:
- Systolic blood pressure for females had a regression line of 124.0 -0.3366*Blood ...
Nanosecond Pulsed Electric Fields Induce Endoplasmic Reticulum Stress Accompanied By Immunogenic Cell Death In Murine Models Of Lymphoma And Colorectal Cancer, Alessandra Rossi, Olga N. Pakhomova, Peter A. Mollica, Maura Casciola, Uma Mangalanathan, Andrei G. Pakhomov, Claudia Muratori
Depending on the initiating stimulus, cancer cell death can be immunogenic or non-immunogenic. Inducers of immunogenic cell death (ICD) rely on endoplasmic reticulum (ER) stress for the trafficking of danger signals such as calreticulin (CRT) and ATP. We found that nanosecond pulsed electric fields (nsPEF), an emerging new modality for tumor ablation, cause the activation of the ER-resident stress sensor PERK in both CT-26 colon carcinoma and EL-4 lymphoma cells. PERK activation correlates with sustained CRT exposure on the cell plasma membrane and apoptosis induction in both nsPEF-treated cell lines. Our results show that, in CT-26 cells, the activity of ...
Effect Of Annealing On The Contact Resistance Of Aluminum On A P-Type Substrate, 2019 Singh Center for Nanotechnology
Effect Of Annealing On The Contact Resistance Of Aluminum On A P-Type Substrate, Shrey Shah, George Patrick Watson
Protocols and Reports
Aluminum contacts are widely used to form both ohmic and rectifying contacts. The process to form these contacts involves annealing, thus it is important to study the effect of annealing on the electrical properties of the contacts. Here, we present a way to measure the contact resistance of aluminum contacts formed on a p-type silicon substrate. It was found the contact resistivity decreased by an average of 18%. It was thus found that annealing at 400°C in a forming gas environment improves the electrical properties of aluminum contacts.
Enhancing Cpr Training: Development And Assessment Of An Affordable, Open-Source Real-Time Feedback Manikin, Anish Sangari, Nitish Sood, Joseph Andrew Hauger
Georgia Undergraduate Research Conference (GURC)
Cardiopulmonary Resuscitation (CPR) is a life-saving technique used in cases of cardiac arrest. Immediate CPR can increase survival rates two to three-fold. While many CPR training courses use non-electronic CPR manikins, recent literature has shown that training on a real-time feedback CPR manikin improves functional outcomes such as chest compression rate and mean tidal volume. However, current commercially available real-time feedback manikins only measure metrics on chest compressions or can be prohibitively expensive ( >$200). Accordingly, we have designed, constructed, and tested a low-cost Arduino microcontroller-based CPR manikin that provides real-time feedback to trainees on eight critical metrics including force of ...
Scan Parameter Optimization For Histotripsy Treatment Of S. Aureus Biofilms On Surgical Mesh, 2019 Iowa State University
Scan Parameter Optimization For Histotripsy Treatment Of S. Aureus Biofilms On Surgical Mesh, Timothy Bigelow, Clayton L. Thomas, Huaiqing Wu
Electrical and Computer Engineering Publications
There is a critical need to develop new noninvasive therapies to treat bacteria biofilms. Previous studies have demonstrated the effectiveness of cavitation-based ultrasound histotripsy to destroy these biofilms. In this study, the dependence of biofilm destruction on multiple scan parameters was assessed by conducting exposures at different scan speeds (0.3-1.4 beam widths/sec), step sizes (0.25-0.5 beam widths), and number of passes of the focus across the mesh (2-6). For each of the exposure conditions, the number of colony forming units (CFUs) remaining on the mesh was quantified. A regression analysis was then conducted revealing that ...
Influence Of Flow Rate, Nozzle Speed, Pitch And The Number Of Passes On The Thickness Of S1805 Photoresist In Suss Microtec As8 Spray Coater, 2019 Singh Center for Nanotechnology
Influence Of Flow Rate, Nozzle Speed, Pitch And The Number Of Passes On The Thickness Of S1805 Photoresist In Suss Microtec As8 Spray Coater, Rohan Sanghvi, Gyuseok Kim
S1805 positive photoresist has been deposited on single crystalline Si wafers using a Suss MicroTec Alta Spray. The inﬂuence of ﬂow rate, nozzle speed, pitch and number of passes on the thickness of the photoresist was studied. Results show that the thickness of S1805 is linearly proportional to the ﬂow rate and number of passes, and inversely proportional to the nozzle speed and pitch.
Antibacterial Properties Of Mussel-Inspired Polydopamine Coatings Prepared By A Simple Two-Step Shaking-Assisted Method, 2019 Michigan Technological University
Antibacterial Properties Of Mussel-Inspired Polydopamine Coatings Prepared By A Simple Two-Step Shaking-Assisted Method, Pegah Kord Fooroshani, Elizabeth Polega, Kevin Thomson, Mohammad Saleh Akram Bhuiyan, Rattapol Pinnaratip, Mikhail Trought, Chito E. Kendrick, Yuesheng Gao, Kahryn Perrine, Lei Pan, Bruce P. Lee
Michigan Tech Publications
A simple two-step, shaking-assisted polydopamine (PDA) coating technique was used to impart polypropylene (PP) mesh with antimicrobial properties. In this modified method, a relatively large concentration of dopamine (20 mg ml−1) was first used to create a stable PDA primer layer, while the second step utilized a significantly lower concentration of dopamine (2 mg ml−1) to promote the formation and deposition of large aggregates of PDA nanoparticles. Gentle shaking (70 rpm) was employed to increase the deposition of PDA nanoparticle aggregates and the formation of a thicker PDA coating with nano-scaled surface roughness (RMS = 110 nm and Ra ...
A Heterogeneous Patient-Specific Biomechanical Model Of The Lung For Tumor Motion Compensation And Effective Lung Radiation Therapy Planning, 2019 The University of Western Ontario
A Heterogeneous Patient-Specific Biomechanical Model Of The Lung For Tumor Motion Compensation And Effective Lung Radiation Therapy Planning, Parya Jafari
Electronic Thesis and Dissertation Repository
Radiation therapy is a main component of treatment for many lung cancer patients. However, the respiratory motion can cause inaccuracies in radiation delivery that can lead to treatment complications. In addition, the radiation-induced damage to healthy tissue limits the effectiveness of radiation treatment. Motion management methods have been developed to increase the accuracy of radiation delivery, and functional avoidance treatment planning has emerged to help reduce the chances of radiation-induced toxicity. In this work, we have developed biomechanical model-based techniques for tumor motion estimation, as well as lung functional imaging. The proposed biomechanical model accurately estimates lung and tumor motion ...
Influence Of Naoh Concentration On Transfer Process Of Graphene, 2019 Singh Center for Nanotechnology
Influence Of Naoh Concentration On Transfer Process Of Graphene, Francisco Saldana, Chengyu Wen, George Patrick Watson
Protocols and Reports
The process of transferring a monolayer of graphene using two diﬀerent concentrations of sodium hydroxide (NaOH) solution unto a silicon dioxide (SiO2) coated Si chip using electrochemistry was performed. The transfer process is crucial for the delamination of a continuous graphene monolayer ﬁlm from copper foil. After examining and inspecting the integrity of the graphene monolayer, it was observed that the lower concentration to NaOH led to slower rate of hydrogen bubble generation; this condition was found to be less destructive and yielded a graphene ﬁlm with fewer visible tears.
Evaluation Activity Of Alanine Aminopeptidase (Aap) In Patients With Renal Dialysis, Purification And Isolation Of Isoenzymes, 2019 Directorate of Baghdad Education Karkh III, Ministry of Education, Baghdad, Iraq
Evaluation Activity Of Alanine Aminopeptidase (Aap) In Patients With Renal Dialysis, Purification And Isolation Of Isoenzymes, Taghreed Mohammad, Sawsan Mahdi, Tammara Al-Kareim, Journal Port Science Research
port Science Research
Investigation Of The Electrode Polarization Effect For Biosensor Applications, 2019 Southern Methodist University
Investigation Of The Electrode Polarization Effect For Biosensor Applications, Anil Koklu
Mechanical Engineering Research Theses and Dissertations
My research focuses on electrokinetic transport. Particularly, in this dissertation, we focus on fabrication and testing of micro electrodes with nanostructured surfaces to minimize the electrode polarization (EP) effects for biosensor applications. In the first study, electrochemical deposition of gold nanoparticles on to planar gold electrodes was used to generate rough surfaces. Dendritic nanostructures that reduced EP up to two orders of magnitude was obtained by optimizing the deposition conditions. These structures also enhanced dielectrophoresis (DEP) response of our bio-chips, making them usable in physiological buffers. In further studies we discovered a universal scaling of EP in the frequency domain ...
Interdependent Mechanisms Of Stress Susceptibility, 2019 University of South Carolina
Interdependent Mechanisms Of Stress Susceptibility, Julie Elaine Finnell
Theses and Dissertations
Social stress is a significant risk factor for the emergence of psychiatric disorders including depression and anxiety. While there are a number of commercially available therapeutic options for the treatment of these disorders, these treatments require weeks of continuous use to produce behavioral efficacy. It has also been suggested that these traditional therapies are only marginally effective in producing complete remission, suggesting that our understanding as it pertains to the mechanisms underlying stressinduced behavioral dysfunction is still in its infancy. In the last few years, inflammation has become a major focus in the field of stress and depression as clinical ...
Improving 3d Printed Prosthetics With Sensors And Motors, 2019 Bridgewater College
Improving 3d Printed Prosthetics With Sensors And Motors, Rachel Zarin
A 3D printed hand and arm prosthetic was created from the idea of adding bionic elements while keeping the cost low. It was designed based on existing models, desired functions, and materials available. A tilt sensor keeps the hand level, two motors move the wrist in two different directions, a limit switch signals the fingers to open and close, and another motor helps open and close the fingers. All sensors and motors were built on a circuit board, programmed using an Arduino, and powered by a battery. Other supporting materials include metal brackets, screws, guitar strings, elastic bands, small clamps ...
The Contribution Of Adipose Tissue From Ovariectomized Mice To Colon Cancer, 2019 University of South Carolina
The Contribution Of Adipose Tissue From Ovariectomized Mice To Colon Cancer, Meredith Smith Carson
Theses and Dissertations
Obesity is considered a major public health concern worldwide due to the increased incidences of metabolic dysfunction and cancer risk. The obese state is, in part, attributable to the overconsumption of calorie-dense foods commonly seen in a standard Western diet, which aids in the progression of chronic, lowgrade inflammation. The role of estrogen varies depending on menopausal status, where estrogen deficiency coupled with increased visceral fat associated with post-menopause leads to increased secretions of pro-inflammatory adipokines and cytokines. However, the presence of estrogen in a premenopausal state has been shown to attenuate the pro-inflammatory response, which has been demonstrated when ...
Astrocyte Sensitivity To Dopamine In Culture And Ex Vivo, 2019 University of South Carolina
Astrocyte Sensitivity To Dopamine In Culture And Ex Vivo, Ashley L. Galloway
Theses and Dissertations
Dopamine is critical for processing of reward and etiology of drug addiction. Astrocytes throughout the brain express dopamine receptors, but consequences of astrocytic dopamine receptor signaling are not well established. This thesis illustrates effects of dopamine on cultured astrocytes and astrocytes in brain slices (ex vivo). In striatal cultures, extracellular dopamine triggered changes in astrocytic Ca2+ signaling and rapid concentration-dependent stellation of astrocytic processes that was not a result of dopamine oxidation, but instead relied on both cAMP-dependent and cAMP-independent dopamine receptor signaling. To isolate possible mechanisms underlying these structural and functional changes, whole-genome RNA sequencing was used in ...