Open Access. Powered by Scholars. Published by Universities.®

Biomedical Commons

Open Access. Powered by Scholars. Published by Universities.®

460 Full-Text Articles 679 Authors 127,358 Downloads 55 Institutions

All Articles in Biomedical

Faceted Search

460 full-text articles. Page 1 of 21.

Image Processing Applications In Real Life: 2d Fragmented Image And Document Reassembly And Frequency Division Multiplexed Imaging, Houman Kamran Habibkhani, Houman Kamran Habibkhani 2018 Louisiana State University

Image Processing Applications In Real Life: 2d Fragmented Image And Document Reassembly And Frequency Division Multiplexed Imaging, Houman Kamran Habibkhani, Houman Kamran Habibkhani

LSU Doctoral Dissertations

In this era of modern technology, image processing is one the most studied disciplines of signal processing and its applications can be found in every aspect of our daily life. In this work three main applications for image processing has been studied.

In chapter 1, frequency division multiplexed imaging (FDMI), a novel idea in the field of computational photography, has been introduced. Using FDMI, multiple images are captured simultaneously in a single shot and can later be extracted from the multiplexed image. This is achieved by spatially modulating the images so that they are placed at different locations in the ...


Deep Gaze Velocity Analysis During Mammographic Reading For Biometric Identification Of Radiologists, Hong-Jun Yoon, Folami Alamudun, Kathy Hudson, Garnetta Morin-Ducote, Georgia Tourassi 2018 Biomedical Sciences, Engineering, and Computing Group Health Data Sciences Institute, Oak Ridge National Laboratory

Deep Gaze Velocity Analysis During Mammographic Reading For Biometric Identification Of Radiologists, Hong-Jun Yoon, Folami Alamudun, Kathy Hudson, Garnetta Morin-Ducote, Georgia Tourassi

Journal of Human Performance in Extreme Environments

Several studies have confirmed that the gaze velocity of the human eye can be utilized as a behavioral biometric or personalized biomarker. In this study, we leverage the local feature representation capacity of convolutional neural networks (CNNs) for eye gaze velocity analysis as the basis for biometric identification of radiologists performing breast cancer screening. Using gaze data collected from 10 radiologists reading 100 mammograms of various diagnoses, we compared the performance of a CNN-based classification algorithm with two deep learning classifiers, deep neural network and deep belief network, and a previously presented hidden Markov model classifier. The study showed that ...


Transcranial Magnetic Stimulation-Coil Design With Improved Focality, Priyam Rastogi, E. G. Lee, Ravi L. Hadimani, David C. Jiles 2018 Iowa State University

Transcranial Magnetic Stimulation-Coil Design With Improved Focality, Priyam Rastogi, E. G. Lee, Ravi L. Hadimani, David C. Jiles

Ravi L. Hadimani

Transcranial Magnetic Stimulation (TMS) is a technique for neuromodulation that can be used as a non-invasive therapy for various neurological disorders. In TMS, a time varying magnetic field generated from an electromagnetic coilplaced on the scalp is used to induce an electric field inside the brain. TMS coilgeometry plays an important role in determining the focality and depth of penetration of the induced electric field responsible for stimulation. Clinicians and basic scientists are interested in stimulating a localized area of the brain,while minimizing the stimulation of surrounding neural networks. In this paper, a novel coil has been proposed, namely ...


Big Data And Parkinson’S Disease: Exploration, Analyses, And Data Challenges, Mahalakshmi SenthilarumugamVeilukandammal, Sree Nilakanta, Baskar Ganapathysubramanian, Vellareddy Anantharam, Anumantha Kanthasamy, Auriel A. Willette 2018 Iowa State University

Big Data And Parkinson’S Disease: Exploration, Analyses, And Data Challenges, Mahalakshmi Senthilarumugamveilukandammal, Sree Nilakanta, Baskar Ganapathysubramanian, Vellareddy Anantharam, Anumantha Kanthasamy, Auriel A. Willette

Mechanical Engineering Conference Presentations, Papers, and Proceedings

In healthcare, a tremendous amount of clinical and laboratory tests, imaging, prescription and medication data are being collected. Big data analytics on these data aim at early detection of disease which will help in developing preventive measures and in improving patient care. Parkinson disease is the second-most common neurodegenerative disorder in the United States. To find a cure for Parkinson's disease biological, clinical and behavioral data of different cohorts are collected, managed and propagated through Parkinson’s Progression Markers Initiative (PPMI). Applying big data technology to this data will lead to the identification of the potential biomarkers of Parkinson ...


Brain Science = Biology + Engineering, Jennifer Welborn, Guangyu Xu, Morton Sternheim, Chris Emery 2018 Amherst Regional Middle School

Brain Science = Biology + Engineering, Jennifer Welborn, Guangyu Xu, Morton Sternheim, Chris Emery

Science and Engineering Saturday Seminars

This interdisciplinary (physical and life sciences) seminar exposes participants to cutting edge research at UMASS, Amherst, on cell imaging using a chip which gathers a variety of data on the activities of single cells. Part of the seminar will be a presentation of current research in this area, followed by hands-on activities and a visit to the lab where this research is conducted. Application of this new technology to brain research will be discussed as well as the NGSS standards alignment and classroom applications at various levels and disciplines.


Adaptive Interventions Treatment Modelling And Regimen Optimization Using Sequential Multiple Assignment Randomized Trials (Smart) And Q-Learning, Abiral Baniya 2018 South Dakota State University

Adaptive Interventions Treatment Modelling And Regimen Optimization Using Sequential Multiple Assignment Randomized Trials (Smart) And Q-Learning, Abiral Baniya

Electronic Theses and Dissertations

Nowadays, pharmacological practices are focused on a single best treatment to treat a disease which sounds impractical as the same treatment may not work the same way for every patient. Thus, there is a need of shift towards more patient-centric rather than disease-centric approach, in which personal characteristics of a patient or biomarkers are used to determine the tailored optimal treatment. The “one size fits all” concept is contradicted by research area of personalized medicine. The Sequential Multiple Assignment Randomized Trial (SMART) is a multi-stage trials to inform the development of dynamic treatment regimens (DTR’s). In SMART, a subject ...


Eeg And Emg Sensorimotor Measurements To Assess Proprioception Following Acl Reconstruction, Teagan Frances Northrup 2018 University of New Hampshire

Eeg And Emg Sensorimotor Measurements To Assess Proprioception Following Acl Reconstruction, Teagan Frances Northrup

Honors Theses and Capstones

The Anterior Cruciate Ligament (ACL) is the primary source of rotational stability in the knee by preventing the tibia from sliding in front of the femur. When the ACL is torn, it typically must be repaired through reconstructive surgery which results in proprioceptive deficiencies in the knee. Proprioception plays an important role in understanding where one’s knee is in space, sensing movement and reacting accordingly. This study examines an alternative method of measuring proprioceptive responses to a stimulus (motion) by using electromyogram (EMG) and electroencephalogram (EEG) signals to observe muscle and brain activity. Two participants (one with an ACL ...


Investigation Of Shape, Position, And Permeability Of Shielding Material In Quadruple Butterfly Coil For Focused Transcranial Magnetic Stimulation, Priyam Rastogi, Bowen Zhang, Yalun Tang, Erik G. Lee, Ravi L. Hadimani, David C. Jiles 2018 Iowa State University

Investigation Of Shape, Position, And Permeability Of Shielding Material In Quadruple Butterfly Coil For Focused Transcranial Magnetic Stimulation, Priyam Rastogi, Bowen Zhang, Yalun Tang, Erik G. Lee, Ravi L. Hadimani, David C. Jiles

Electrical and Computer Engineering Publications

Transcranial magnetic stimulation has been gaining popularity in the therapy for several neurological disorders. A time-varying magnetic field is used to generate electric field in the brain. As the development of TMS methods takes place, emphasis on the coil design increases in order to improve focal stimulation. Ideally reduction of stimulation of neighboring regions of the target area is desired. This study, focused on the improvement of the focality of the Quadruple Butterfly Coil (QBC) with supplemental use of different passive shields. Parameters such as shape, position and permeability of the shields have been explored to improve the focus of ...


Chronic Risk And Disease Management Model Using Structured Query Language And Predictive Analysis, Mamata Ojha 2018 South Dakota State University

Chronic Risk And Disease Management Model Using Structured Query Language And Predictive Analysis, Mamata Ojha

Electronic Theses and Dissertations

Individuals with chronic conditions are the ones who use health care most frequently and more than 50% of top ten causes of death are chronic diseases in United States and these members always have health high risk scores. In the field of population health management, identifying high risk members is very important in terms of patient health care, disease management and cost management. Disease management program is very effective way of monitoring and preventing chronic disease and health related complications and risk management allows physicians and healthcare companies to reduce patient’s health risk, help identifying members for care/disease ...


Optimal Decomposition Strategy For Tree Edit Distance, Shaofeng Jiang 2017 The University of Western Ontario

Optimal Decomposition Strategy For Tree Edit Distance, Shaofeng Jiang

Electronic Thesis and Dissertation Repository

An ordered labeled tree is a tree where the left-to-right order among siblings is significant. Given two ordered labeled trees, the edit distance between them is the minimum cost edit operations that convert one tree to the other.

In this thesis, we present an algorithm for the tree edit distance problem by using the optimal tree decomposition strategy. By combining the vertical compression of trees with optimal decomposition we can significantly reduce the running time of the algorithm. We compare our method with other methods both theoretically and experimentally. The test results show that our strategies on compressed trees are ...


Skills Assessment In Arthroscopic Surgery By Processing Kinematic, Force, And Bio-Signal Data, Behnaz Poursartip 2017 The University of Western Ontario

Skills Assessment In Arthroscopic Surgery By Processing Kinematic, Force, And Bio-Signal Data, Behnaz Poursartip

Electronic Thesis and Dissertation Repository

Arthroscopic surgery is a type of Minimally Invasive Surgery (MIS) performed in human joints, which can be used for diagnostic or treatment purposes. The nature of this type of surgery makes it such that surgeons require extensive training to become experts at performing surgical tasks in tight environments and with reduced force feedback. MIS increases the possibility of erroneous actions, which could result in injury to the patient. Many of these injuries can be prevented by implementing appropriate training and skills assessment methods.

Various performance methods, including Global Rating Scales and technical measures, have been proposed in the literature. However ...


Synthesis And Characterization Of Thermoresponsive Hydrogels Based On N-Isopropylacrylamide Crosslinked With 4,4′-Dihydroxybiphenyl Diacrylate, Shuo Tang, Martha Floy, Rohit Bhandari, Manjula Sunkara, Andrew J. Morris, Thomas D. Dziubla, J. Zach Hilt 2017 University of Kentucky

Synthesis And Characterization Of Thermoresponsive Hydrogels Based On N-Isopropylacrylamide Crosslinked With 4,4′-Dihydroxybiphenyl Diacrylate, Shuo Tang, Martha Floy, Rohit Bhandari, Manjula Sunkara, Andrew J. Morris, Thomas D. Dziubla, J. Zach Hilt

Chemical and Materials Engineering Faculty Publications

A novel crosslinker [4,4′-dihydroxybiphenyl diacrylate (44BDA)] was developed, and a series of temperature-responsive hydrogels were synthesized through free radical polymerization of N-isopropylacrylamide (NIPAAm) with 44BDA. The temperature-responsive behavior of the resulting gels was characterized by swelling studies, and the lower critical solution temperature (LCST) of the hydrogels was characterized through differential scanning calorimetry. Increased content of 44BDA led to a decreased swelling ratio and shifted the LCST to lower temperatures. These novel hydrogels also displayed resiliency through multiple swelling–deswelling cycles, and their temperature responsiveness was reversible. The successful synthesis of NIPAAm-based hydrogels crosslinked with 44BDA has ...


Portable 6 Lead 4 Electrode Ekg, Cody Magnuson, Wes Archbold 2017 California Polytechnic State University, San Luis Obispo

Portable 6 Lead 4 Electrode Ekg, Cody Magnuson, Wes Archbold

Electrical Engineering

This project focused on designing a small, portable, 6 lead 4 electrode electrocardiogram (EKG) machine with enough accuracy and resolution to successfully diagnose clinical issues. The electrical design used to measure signals originating from the heart can be broken up into three stages. The first stage is the human device interface. Next, is the analog block that filters out common mode noise and conditions the signal for digital encoding using instrumentation amplifiers, a right leg circuit, high pass, low pass, and an amplifier. This circuit filters all frequencies above and below the frequency band of meaningful data (1-160Hz), rejects signals ...


Design And Evaluation Of Neurosurgical Training Simulator, Trinette L. Wright 2017 Western University

Design And Evaluation Of Neurosurgical Training Simulator, Trinette L. Wright

Electronic Thesis and Dissertation Repository

Surgical simulators are becoming more important in surgical training. Consumer smartphone technology has improved to allow deployment of VR applications and are now being targeted for medical training simulators. A surgical simulator has been designed using a smartphone, Google cardboard 3D glasses, and the Leap Motion (LM) hand controller. Two expert and 16 novice users were tasked with completing the same pointing tasks using both the LM and the medical simulator NeuroTouch. The novice users had an accuracy of 0.2717 bits (SD 0.3899) and the experts had an accuracy of 0.0925 bits (SD 0.1210) while using ...


Technobiology Paradigm In Nanomedicine: Treating Cancer With Magnetoelectric Nanoparticles, Emmanuel Stimphil 2017 Florida International University

Technobiology Paradigm In Nanomedicine: Treating Cancer With Magnetoelectric Nanoparticles, Emmanuel Stimphil

FIU Electronic Theses and Dissertations

Today, cancer is the world’s deadliest disease. Despite significant progress to find a cure, especially over the last decade, with immunotherapy rapidly becoming the state of the art, major open questions remain. Each successful therapy is not only limited to a few cancers but also has relatively low specificity to target cancer cells; although cancer cells can indeed be eradicated, many normal cells are sacrificed as collateral damage. To fill this gap, we have developed a class of multiferroic nanostructures known as magnetoelectric nanoparticles (MENs) that can be used to enable externally controlled high-specificity targeted delivery and release of ...


Force Sensing Surgical Grasper With Folding Capacitive Sensor, Dave BP Tripp 2017 The University of Western Ontario

Force Sensing Surgical Grasper With Folding Capacitive Sensor, Dave Bp Tripp

Electronic Thesis and Dissertation Repository

Minimally-invasive surgery (MIS) has brought many benefits to the operating room, however, MIS procedures result in an absence of force feedback, and surgeons cannot as accurately feel the tissue they are working on, or the forces that they are applying. One of the barriers to introducing MIS instruments with force feedback systems is the high cost of manufacturing and assembly. Instruments must also be sterilized before every use, a process that can destroy embedded sensing systems. An instrument that can be disposed of after a single use and produced in bulk at a low cost is desirable. Printed circuit micro-electro-mechanical ...


Pulmonary Image Segmentation And Registration Algorithms: Towards Regional Evaluation Of Obstructive Lung Disease, Fumin Guo 2017 The University of Western Ontario

Pulmonary Image Segmentation And Registration Algorithms: Towards Regional Evaluation Of Obstructive Lung Disease, Fumin Guo

Electronic Thesis and Dissertation Repository

Pulmonary imaging, including pulmonary magnetic resonance imaging (MRI) and computed tomography (CT), provides a way to sensitively and regionally measure spatially heterogeneous lung structural-functional abnormalities. These unique imaging biomarkers offer the potential for better understanding pulmonary disease mechanisms, monitoring disease progression and response to therapy, and developing novel treatments for improved patient care. To generate these regional lung structure-function measurements and enable broad clinical applications of quantitative pulmonary MRI and CT biomarkers, as a first step, accurate, reproducible and rapid lung segmentation and registration methods are required. In this regard, we first developed a 1H MRI lung segmentation algorithm that ...


Gui For Mri-Compatible Neural Stimulator And Recorder, Soo Han Soon, Nishant Babaria, Ranajay Mandal, Zhongming Liu 2017 Purdue University

Gui For Mri-Compatible Neural Stimulator And Recorder, Soo Han Soon, Nishant Babaria, Ranajay Mandal, Zhongming Liu

The Summer Undergraduate Research Fellowship (SURF) Symposium

Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) are useful tools to analyze brain activities given active stimulation. However, the electromagnetic noise from the MRI distorts the brain signal recording and damages the subject with excessive heat generated on the electrodes attached to the skin. MRI-compatible recording and stimulation systems previously developed at LIBI lab were capable of removing the electromagnetic noise during the imaging process. Previously, the hardware systems had required the integrative software that could control both circuits simultaneously and enable users to easily change recording and stimulation parameters. Graphical user interface (GUI) programmed with computer language informed ...


Optimization Of Prosthetic Hands: Utilizing Modularity To Improve Grip Force, Grasp, And Versatility, Jordan William Harris 2017 University of Nevada, Las Vegas

Optimization Of Prosthetic Hands: Utilizing Modularity To Improve Grip Force, Grasp, And Versatility, Jordan William Harris

UNLV Theses, Dissertations, Professional Papers, and Capstones

It has been demonstrated that although many varieties of upper limb prosthetics exist, commercially available prosthetics are outdated and unsatisfactory. Ineffectiveness and limitations have led to some prosthesis wearers having to own multiple devices, whereas others have given up on them entirely. Even though ample research has been conducted to design and test new hand designs, the industry appears to rest in an overall stagnated state.

It was proposed here, that one problem with prosthetic research is an excess of variables involved in testing, and therefore the improper application of the scientific method. It seems that each time a research ...


Design And Implementation Of A Low‐Power Wireless Respiration Monitoring Sensor, Ifana Mahbub 2017 Univeristy of Tennessee, Knoxville

Design And Implementation Of A Low‐Power Wireless Respiration Monitoring Sensor, Ifana Mahbub

Doctoral Dissertations

Wireless devices for monitoring of respiration activities can play a major role in advancing modern home-based health care applications. Existing methods for respiration monitoring require special algorithms and high precision filters to eliminate noise and other motion artifacts. These necessitate additional power consuming circuitry for further signal conditioning. This dissertation is particularly focused on a novel approach of respiration monitoring based on a PVDF-based pyroelectric transducer. Low-power, low-noise, and fully integrated charge amplifiers are designed to serve as the front-end amplifier of the sensor to efficiently convert the charge generated by the transducer into a proportional voltage signal. To transmit ...


Digital Commons powered by bepress