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A Scalable Method For Solving High-Dimensional Continuous Pomdps Using Local Approximation, Tom Erez, William D. Smart 2010 Washington University in St Louis

A Scalable Method For Solving High-Dimensional Continuous Pomdps Using Local Approximation, Tom Erez, William D. Smart

All Computer Science and Engineering Research

Partially-Observable Markov Decision Processes (POMDPs) are typically solved by finding an approximate global solution to a corresponding belief-MDP. In this paper, we offer a new planning algorithm for POMDPs with continuous state, action and observation spaces. Since such domains have an inherent notion of locality, we can find an approximate solution using local optimization methods. We parameterize the belief distribution as a Gaussian mixture, and use the Extended Kalman Filter (EKF) to approximate the belief update. Since the EKF is a first-order filter, we can marginalize over the observations analytically. By using feedback control and state estimation during policy execution ...


Integrated Circuit Implementation For A Gan Hfet Driver Circuit, Bo Wang, Jason D. Bakos, Antonello Monti 2010 University of South Carolina - Columbia

Integrated Circuit Implementation For A Gan Hfet Driver Circuit, Bo Wang, Jason D. Bakos, Antonello Monti

Faculty Publications

This paper presents the design and implementation of a new integrated circuit (IC) that is suitable for driving the new generation of high-frequency GaN HFETs. The circuit, based upon a resonant switching transition technique, is first briefly described and then discussed in detail, focusing on the design process practical considerations. A new level-shifter topology, used to generate the zero and negative gate-source voltages required to switch the GaN HFET, is introduced and analyzed. The experimental measurements included in this paper report the results of tests carried out on an IC designed and fabricated as part of the multiproject die in ...


Discrete Coordinate Transformation For Designing All-Dielectric Flat Antennas, Wenxuan Tang, Christos Argyropoulos, Efthymios Kallos, Wei Song, Yang Hao 2010 University of London

Discrete Coordinate Transformation For Designing All-Dielectric Flat Antennas, Wenxuan Tang, Christos Argyropoulos, Efthymios Kallos, Wei Song, Yang Hao

Faculty Publications from the Department of Electrical and Computer Engineering

Transformation electromagnetics provides a practical approach to control electromagnetic fields at will. Based on this principle, novel devices such as the invisible cloak have been proposed. Here we examine the extension of this technique as applied to the design of flat devices in antenna systems. A method using discrete coordinate transformation is proposed, which allows the conversion of conventional devices with curved shapes into flat systems, while preserving their non-dispersive, isotropic, broadband, and lossless properties. Two specific design examples, a flat reflector and a flat lens embedded in free space, are presented. To avoid the loss and narrow bandwidth issues ...


Bioinformatic Identification And Characterization Of Human Endothelial Cell-Restricted Genes, Manoj Bhasin, Lei Yuan, Derin B. Keskin, Hasan H. Otu, Towia A. Libermann, Peter Oettgen 2010 Harvard Medical School

Bioinformatic Identification And Characterization Of Human Endothelial Cell-Restricted Genes, Manoj Bhasin, Lei Yuan, Derin B. Keskin, Hasan H. Otu, Towia A. Libermann, Peter Oettgen

Faculty Publications from the Department of Electrical and Computer Engineering

Background: In this study, we used a systematic bioinformatics analysis approach to elucidate genes that exhibit an endothelial cell (EC) restricted expression pattern, and began to define their regulation, tissue distribution, and potential biological role.

Results:Using a high throughput microarray platform, a primary set of 1,191 transcripts that are enriched in different primary ECs compared to non-ECs was identified (LCB >3, FDR

Conclusion: The study provides an initial catalogue of EC-restricted genes most of which are ubiquitously expressed in different endothelial cells.


Clustering Of Protein Families Into Functional Subtypes Using Relative Complexity Measure With Reduced Amino Acid Alphabets, Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman 2010 Sabanci University

Clustering Of Protein Families Into Functional Subtypes Using Relative Complexity Measure With Reduced Amino Acid Alphabets, Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman

Faculty Publications from the Department of Electrical and Computer Engineering

Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize multiple alignment of sequences and are based on an evolutionary model. However, multiple alignment is not an automated procedure and requires human intervention to maintain alignment integrity and to produce phylogenies consistent with the functional splits in underlying sequences. To address this problem, we propose to use the alignment-free Relative Complexity Measure (RCM) combined with reduced amino acid alphabets to cluster protein families into functional subtypes purely on sequence criteria. Comparison with an alignment-based approach was ...


Data Compression Concepts And Algorithms And Their Applications To Bioinformatics, Ozkan U. Nalbantoglu, David J. Russell, Khalid Sayood 2010 University of Nebraska-Lincoln

Data Compression Concepts And Algorithms And Their Applications To Bioinformatics, Ozkan U. Nalbantoglu, David J. Russell, Khalid Sayood

Faculty Publications from the Department of Electrical and Computer Engineering

Data compression at its base is concerned with how information is organized in data. Understanding this organization can lead to efficient ways of representing the information and hence data compression. In this paper we review the ways in which ideas and approaches fundamental to the theory and practice of data compression have been used in the area of bioinformatics. We look at how basic theoretical ideas from data compression, such as the notions of entropy, mutual information, and complexity have been used for analyzing biological sequences in order to discover hidden patterns, infer phylogenetic relationships between organisms and study viral ...


Tob1 Is A Constitutively Expressed Repressor Of Liver Regeneration, Karen J. Ho, Nhue L. Do, Hasan H. Otu, Martin J. Dib, Xianghui Ren, Keiichi Enjyoji, Simon C. Robson, Ernest F. Terwilliger, Seth J. Karp 2010 Beth Israel Deaconess Medical Center

Tob1 Is A Constitutively Expressed Repressor Of Liver Regeneration, Karen J. Ho, Nhue L. Do, Hasan H. Otu, Martin J. Dib, Xianghui Ren, Keiichi Enjyoji, Simon C. Robson, Ernest F. Terwilliger, Seth J. Karp

Faculty Publications from the Department of Electrical and Computer Engineering

How proliferative and inhibitory signals integrate to control liver regeneration remains poorly understood. A screen for antiproliferative factors repressed after liver injury identified transducer of ErbB2.1 (Tob1), a member of the PC3/BTG1 family of mito-inhibitory molecules as a target for further evaluation. Tob1 protein decreases after 2/3 hepatectomy in mice secondary to posttranscriptional mechanisms. Deletion of Tob1 increases hepatocyte proliferation and accelerates restoration of liver mass after hepatectomy. Down-regulation of Tob1 is required for normal liver regeneration, and Tob1 controls hepatocyte proliferation in a dose-dependent fashion. Tob1 associates directly with both Caf1 and cyclindependent kinase (Cdk) 1 ...


Iterative Signal Processing In Communications, Christian Schlegel, Peter Hoeher, Owe Axelsson, Lance C. Pérez 2010 University of Alberta

Iterative Signal Processing In Communications, Christian Schlegel, Peter Hoeher, Owe Axelsson, Lance C. Pérez

Faculty Publications from the Department of Electrical and Computer Engineering

Iterative signal processing in communications has experienced an explosive rise in popularity in recent years. The catalytic origins of this paradigm-shifting new philosophy among communications experts can be traced to the invention of turbo coding, and the subsequent rediscovery of low-density parity check (LDPC) coding, both in the field of error control coding. Both systems rely on iterative decoding algorithms to achieve their astounding performance. However, iterative signal processing is not confined to the decoding of error control codes and rather quickly spread to many other possible applications. The purpose of this special issue is to examine the concept of ...


Protein Adsorption On And Swelling Of Polyelectrolyte Brushes: A Simultaneous Ellipsometry-Quartz Crystal Microbalance Study, Eva Bittrich, Keith B. Rodenhausen Jr., Klaus-Jochen Eichhorn, Tino Hofmann, Mathias Schubert, Manfred Stamm, Petra Uhlmann 2010 Leibniz Institute of Polymer Research Dresden

Protein Adsorption On And Swelling Of Polyelectrolyte Brushes: A Simultaneous Ellipsometry-Quartz Crystal Microbalance Study, Eva Bittrich, Keith B. Rodenhausen Jr., Klaus-Jochen Eichhorn, Tino Hofmann, Mathias Schubert, Manfred Stamm, Petra Uhlmann

Faculty Publications from the Department of Electrical and Computer Engineering

With a coupled spectroscopic ellipsometry-quartz crystal microbalance with dissipation (QCM-D) experimental setup, quantitative information can be obtained about the amount of buffer components (water molecules and ions) coupled to a poly(acrylic acid) (PAA) brush surface in swelling and protein adsorption processes. PAA Guiselin brushes with more than one anchoring point per single polymer chain were prepared. For the swollen brushes a high amount of buffer was found to be coupled to the brush-solution interface in addition to the content of buffer inside the brush layer. Upon adsorption of bovine serum albumin the further incorporation of buffer molecules into the ...


Prognosis: A Wearable System For Health Monitoring Of People At Risk, Alexandros A. Pantelopoulos 2010 Wright State University

Prognosis: A Wearable System For Health Monitoring Of People At Risk, Alexandros A. Pantelopoulos

Browse all Theses and Dissertations

Wearable Health Monitoring Systems (WHMS) have drawn a lot of attention from the research community and the industry during the last decade. The development of such systems has been motivated mainly by increasing healthcare costs and by the fact that the world population is ageing. In addition to that, RandD in WHMS has been propelled by recent technological advances in miniature bio-sensing devices, smart textiles, microelectronics and wireless communications techniques. These portable health systems can comprise various types of small physiological sensors, which enable continuous monitoring of a variety of human vital signs and other physiological parameters such as heart ...


Semantic Provenance: Modeling, Querying, And Application In Scientific Discovery, Satya Sanket Sahoo 2010 Wright State University

Semantic Provenance: Modeling, Querying, And Application In Scientific Discovery, Satya Sanket Sahoo

Browse all Theses and Dissertations

Provenance metadata, describing the history or lineage of an entity, is essential for ensuring data quality, correctness of process execution, and computing trust values. Traditionally, provenance management issues have been dealt with in the context of workflow or relational database systems. However, existing provenance systems are inadequate to address the requirements of an emerging set of applications in the new eScience or Cyberinfrastructure paradigm and the Semantic Web. Provenance in these applications incorporates complex domain semantics on a large scale with a variety of uses, including accurate interpretation by software agents, trustworthy data integration, reproducibility, attribution for commercial or legal ...


Understanding User-Generated Content On Social Media, Bala Meenakshi Nagarajan 2010 Wright State University

Understanding User-Generated Content On Social Media, Bala Meenakshi Nagarajan

Browse all Theses and Dissertations

Over the last few years, there has been a growing public and enterprise fascination with 'social media' and its role in modern society. At the heart of this fascination is the ability for users to participate, collaborate, consume, create and share content via a variety of platforms such as blogs, micro-blogs, email, instant messaging services, social network services, collaborative wikis, social bookmarking sites, and multimedia sharing sites.

This dissertation is devoted to understanding informal user-generated textual content on social media platforms and using the results of the analysis to build Social Intelligence Applications.

The body of research presented in this ...


Visualization Of Complex Unsteady 3d Flow: Flowing Seed Points And Dynamically Evolving Seed Curves With Applications To Vortex Visualization In Cfd Simulations Of Ultra Low Reynolds Number Insect Flight, Christopher M. Koehler 2010 Wright State University

Visualization Of Complex Unsteady 3d Flow: Flowing Seed Points And Dynamically Evolving Seed Curves With Applications To Vortex Visualization In Cfd Simulations Of Ultra Low Reynolds Number Insect Flight, Christopher M. Koehler

Browse all Theses and Dissertations

Three dimensional integration-based geometric visualization is a very powerful tool for analyzing flow phenomena in time dependent vector fields. Streamlines in particular have many perceptual benefits due to their ability to provide a snapshot of the vectors near key features of complex 3D flows at any instant in time. However, streamlines do not lend themselves well to animation. Subtle changes in the vector field at each time step lead to increasingly large changes between streamlines with the same seed point the longer they are integrated. Path lines, which show particle trajectories over time suffer from similar problems when attempting to ...


Patterns Of Dipeptide Usage For Gene Prediction, Dayananda Sagar Gangadharaiah 2010 Wright State University

Patterns Of Dipeptide Usage For Gene Prediction, Dayananda Sagar Gangadharaiah

Browse all Theses and Dissertations

As the number of complete genomes that have been sequenced continues to grow rapidly, the identification of genes regions in DNA sequence data remains one of the most important open problems in bio-informatics. Improving the accuracy of such gene finding tools by a small percentage would affect accurate predictions of many genes of an organism (Zhu et al., 2010). This thesis presents a novel approach for identifying coding regions of a genome based on dipeptide usage.

The patterns in dipeptide usage are used to discriminate between coding and non-coding DNA regions. Two sample T-tests are used as tests of significance ...


Innovations In The Internet’S Architecture That Challenge The Status Quo, Christopher S. Yoo 2010 University of Pennsylvania Law School

Innovations In The Internet’S Architecture That Challenge The Status Quo, Christopher S. Yoo

Faculty Scholarship at Penn Law

The current debate over broadband policy has largely overlooked a number of changes to the architecture of the Internet that have caused the price paid by and quality of service received by traffic traveling across the Internet to vary widely. Topological innovations, such as private peering, multihoming, secondary peering, server farms, and content delivery networks, have caused the Internet’s traditionally hierarchical architecture to be replaced by one that is more heterogeneous. Moreover, network providers have begun to employ an increasingly varied array of business arrangements. Some of these innovations are responses to the growing importance of peer-to-peer technologies. Others ...


Real-Time 3-D Reconstruction By Means Of Structured Light Illumination, Kai Liu 2010 University of Kentucky

Real-Time 3-D Reconstruction By Means Of Structured Light Illumination, Kai Liu

University of Kentucky Doctoral Dissertations

Structured light illumination (SLI) is the process of projecting a series of light striped patterns such that, when viewed at an angle, a digital camera can reconstruct a 3-D model of a target object's surface. But by relying on a series of time multiplexed patterns, SLI is not typically associated with video applications. For this purpose of acquiring 3-D video, a common SLI technique is to drive the projector/camera pair at very high frame rates such that any object's motion is small over the pattern set. But at these high frame rates, the speed at which the ...


Unified Role Assignment Framework For Wireless Sensor Networks, Manish Mahendra Kumar Kochhal 2010 Wayne State University

Unified Role Assignment Framework For Wireless Sensor Networks, Manish Mahendra Kumar Kochhal

Wayne State University Dissertations

Wireless sensor networks are made possible by the continuing improvements in embedded sensor, VLSI, and wireless radio technologies. Currently, one of the important challenges in sensor networks is the design of a systematic network management framework that allows localized and collaborative resource control uniformly across all application services such as sensing, monitoring, tracking, data aggregation, and routing.

The research in wireless sensor networks is currently oriented toward a cross-layer network abstraction that supports appropriate fine or course grained resource controls for energy efficiency. In that regard, we have designed a unified role-based service paradigm for wireless sensor networks. We pursue ...


Robotic Goal-Based Semi-Autonomous Algorithms Improve Remote Operator Performance, Shawn Hunt 2010 Wayne State University

Robotic Goal-Based Semi-Autonomous Algorithms Improve Remote Operator Performance, Shawn Hunt

Wayne State University Dissertations

The focus of this research was to determine if reliable goal-based semi-autonomous algorithms are able to improve remote operator performance or not. Two semi-autonomous algorithms were examined: visual servoing and visual dead reckoning. Visual servoing uses computer vision techniques to generate movement commands while using internal properties of the camera combined with sensor data that tell the robot its current position based on its previous position. This research shows that the semi-autonomous algorithms developed increased performance in a measurable way. An analysis of tracking algorithms for visual servoing was conducted and tracking algorithms were enhanced to make them as robust ...


Augmented Reality Navigation Interfaces Improve Human Performance In End-Effector Controlled Telerobotics, Keshav Chintamani 2010 Wayne State University

Augmented Reality Navigation Interfaces Improve Human Performance In End-Effector Controlled Telerobotics, Keshav Chintamani

Wayne State University Dissertations

On the International Space Station (ISS) and space shuttles, the National Aeronautics and Space Administration (NASA) has used robotic manipulators extensively to perform payload handling and maintenance tasks. Teleoperating robots require expert skills and optimal performance is crucial to mission completion and crew safety. Degradation in performance is observed when manual control is mediated through remote camera views, resulting in poor end-effector navigation quality and extended task completion times. This thesis explores the application of three-dimensional augmented reality (AR) interfaces specifically designed to improve human performance during end-effector controlled teleoperations. A modular telerobotic test bed was developed for this purpose ...


Filter Scheduling Function Model In Internet Server: Resource Configuration, Performance Evaluation And Optimal Scheduling, Minghua Xu 2010 Wayne State University

Filter Scheduling Function Model In Internet Server: Resource Configuration, Performance Evaluation And Optimal Scheduling, Minghua Xu

Wayne State University Dissertations

ABSTRACT

FILTER SCHEDULING FUNCTION MODEL IN INTERNET SERVER:

RESOURCE CONFIGURATION, PERFORMANCE EVALUATION AND

OPTIMAL SCHEDULING

by

MINGHUA XU

August 2010

Advisor: Dr. Cheng-Zhong Xu

Major: Computer Engineering

Degree: Doctor of Philosophy

Internet traffic often exhibits a structure with rich high-order statistical properties like selfsimilarity

and long-range dependency (LRD). This greatly complicates the problem of

server performance modeling and optimization. On the other hand, popularity of Internet

has created numerous client-server or peer-to-peer applications, with most of them,

such as online payment, purchasing, trading, searching, publishing and media streaming,

being timing sensitive and/or financially critical. The scheduling policy in Internet ...


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