Incorporating Solvent-Dependent Kinetics To Design A Multistage, Continuous, Combined Cooling/Antisolvent Crystallization Process,
2019
Rowan University
Incorporating Solvent-Dependent Kinetics To Design A Multistage, Continuous, Combined Cooling/Antisolvent Crystallization Process, Jennifer M. Schall, Gerard Capellades, Jasdeep S. Mandur, Richard D. Braatz, Allan S. Myerson
Henry M. Rowan College of Engineering Faculty Scholarship
Combined cooling and antisolvent crystallization enables crystallization of many pharmaceutical products, but its process design typically neglects solvent composition influences on crystallization kinetics. This paper evaluates the influence of solvent-dependent nucleation and growth kinetics on the design of optimal, multistage mixed-suspension, mixed-product removal (MSMPR) crystallization cascades. The ability to independently select temperature and solvent compositions in each stage of the cascade serves to greatly expand the attainable region for a two-stage cascade, with diminishing returns for additional stages. Failure to include solvent-dependent kinetics can result in simulating incorrect attainable regions, active pharmaceutical ingredient (API) yields, and crystal size distributions. This …
Computational And Experimental Approach To Understanding The Structural Interplay Of Self-Assembled End-Terminated Alkanethiolates On Gold Surfaces,
2019
Jackson State University
Computational And Experimental Approach To Understanding The Structural Interplay Of Self-Assembled End-Terminated Alkanethiolates On Gold Surfaces, Juganta K. Roy, Erick S. Vasquez, Henry P. Pinto, Swati Kumari, Keisha B. Walters, Jerzy Leszcynski
Chemical and Materials Engineering Faculty Publications
Applications of self-assembled monolayers (SAMs) on surfaces are prevalent in modern technologies and drives the need for a better understanding of the surface domain architecture of SAMs. To explore structural interaction at the interface between gold surfaces and a hydroxyl-terminated alkanethiol, 11-hydroxy-1-undecanethiol, (C11TH) we have employed a combined computational and experimental approach. Density functional theory (DFT) calculations were carried out on the thiol–gold interface using both the Perdew–Burke–Ernzerhof (PBE) and van der Waals (optB86b) density functionals. Our ab initio molecular dynamics (AIMD) simulations revealed that the interface consists of four different distinguished phases, each with different C11TH orientations. Experiments involved …
Phase Rule Classification Of Physical And Chemical Critical Effects In Liquid Mixtures,
2019
University of Alabama in Huntsville
Phase Rule Classification Of Physical And Chemical Critical Effects In Liquid Mixtures, James K. Baird, Xingjian Wang, Joshua R. Lang, Pauline Norris
PRC-Affiliated Research
The isobaric heat capacity and the coefficient of thermal expansion of a binary liquid mixture with a critical point of solution diverge as functions of temperature in the critical region. When the same liquids are used as solvents for chemical reactions, the van't Hoff plot of the extent of reaction diverges in the critical region. According to the phase rule, the physical and chemical properties are isomorphic in the sense that in each case the critical behavior is determined by three fixed thermodynamic intensive variables.
Phase Rule Classification Of Physical And Chemical Critical Effects In Liquid Mixtures,
2019
University of Alabama in Huntsville
Phase Rule Classification Of Physical And Chemical Critical Effects In Liquid Mixtures, James K. Baird, Xingjian Wang, Joshua R. Lang, Pauline Norris
PRC-Affiliated Research
The isobaric heat capacity and the coefficient of thermal expansion of a binary liquid mixture with a critical point of solution diverge as functions of temperature in the critical region. When the same liquids are used as solvents for chemical reactions, the van't Hoff plot of the extent of reaction diverges in the critical region. According to the phase rule, the physical and chemical properties are isomorphic in the sense that in each case the critical behavior is determined by three fixed thermodynamic intensive variables.
Phase Rule Classification Of Physical And Chemical Critical Effects In Liquid Mixtures,
2019
University of Alabama in Huntsville
Phase Rule Classification Of Physical And Chemical Critical Effects In Liquid Mixtures, James K. Baird, Xingjian Wang, Joshua R. Lang, Pauline Norris
PRC-Affiliated Research
The isobaric heat capacity and the coefficient of thermal expansion of a binary liquid mixture with a critical point of solution diverge as functions of temperature in the critical region. When the same liquids are used as solvents for chemical reactions, the van't Hoff plot of the extent of reaction diverges in the critical region. According to the phase rule, the physical and chemical properties are isomorphic in the sense that in each case the critical behavior is determined by three fixed thermodynamic intensive variables.
Multiphase Cfd Modeling In Particle-Laden Flows,
2019
Louisiana State University and Agricultural and Mechanical College
Multiphase Cfd Modeling In Particle-Laden Flows, Zhizhong Ding
LSU Doctoral Dissertations
Multiphase modeling is prevalent and useful in solving problems involving multiphase interactions such as fluid and solid. Applications conclude but not limited to fluidized bed, hydraulic conveying, and many others. Modeling techniques with multiple scales can provide various states of details with diverse computational resources used. In this dissertation, two CFD multiphase models are used to disclose interaction details in the particulate system. Two-Fluid Model is used to solve pulsed fluidized bed problem and immersed boundary method based direct numerical method is used to solve particle’s behavior in shear flow. Getting a better understanding of these problems to help to …
Catalyst-Assisted Transformation Of Shale Gas To Transportation Fuels: Performance Of A Single-Site Cobalt Catalyst In Dehydrogenation And Oligomerization Processes,
2019
Purdue University
Catalyst-Assisted Transformation Of Shale Gas To Transportation Fuels: Performance Of A Single-Site Cobalt Catalyst In Dehydrogenation And Oligomerization Processes, Ethan Edwards
The Journal of Purdue Undergraduate Research
No abstract provided.
In-Line Monitoring Of Lubricant Addition Through Passive Vibration Measurements In A V-Blender,
2019
The University of Western Ontario
In-Line Monitoring Of Lubricant Addition Through Passive Vibration Measurements In A V-Blender, Austin Cameron
Electronic Thesis and Dissertation Repository
Process analytical technologies can improve product monitoring and process efficiency in pharmaceutical manufacturing. Passive vibration measurements were evaluated for their potential as a technique to monitor lubricant dispersal in a V-blender. An accelerometer was attached to the lid of a V-blender shell to measure vibrations from particle collisions. Lubricants formed a layer around the surface of particles, altering energy dissipation upon impact. With mixing, vibrational amplitudes approached a stable value indicating a mixing end-point. Mixing profiles were sensitive to changes in particle type, particle size and distribution, and lubricant concentrations for ideal particles and pharmaceutical granules. Axial loading configurations provided …
Role Of Submicrometer Particles In Advanced Technologies Of Carbon Capture,
2019
Washington University in St. Louis
Role Of Submicrometer Particles In Advanced Technologies Of Carbon Capture, Zhichao Li
McKelvey School of Engineering Theses & Dissertations
Oxy-combustion and post-combustion carbon capture technologies are two of the most promising strategies for carbon capture and storage (CCS), which is a commonly accepted approach to address the challenge of climate change. Pressurized oxy-combustion has been actively studied due to its great potential to enhance the power plant energy efficiency by recovering latent heat from water vapor condensation without incurring additional gas compression cost. On the other hand, amine-based CO2 scrubbers have been demonstrated to have high removal efficiency of CO2 with the possibility to recycle amine solutions, which makes the technology a promising candidate for post-combustion carbon capture. Nonetheless, …
Role Of Submicrometer Particles In Advanced Technologies Of Carbon Capture,
2019
Washington University in St. Louis
Role Of Submicrometer Particles In Advanced Technologies Of Carbon Capture, Zhichao Li
McKelvey School of Engineering Theses & Dissertations
Oxy-combustion and post-combustion carbon capture technologies are two of the most promising strategies for carbon capture and storage (CCS), which is a commonly accepted approach to address the challenge of climate change. Pressurized oxy-combustion has been actively studied due to its great potential to enhance the power plant energy efficiency by recovering latent heat from water vapor condensation without incurring additional gas compression cost. On the other hand, amine-based CO2 scrubbers have been demonstrated to have high removal efficiency of CO2 with the possibility to recycle amine solutions, which makes the technology a promising candidate for post-combustion carbon capture. Nonetheless, …
Interfacial Interactions And Dynamic Adhesion Of Synthetic And Living Colloids In Flow,
2019
University of Massachusetts Amherst
Interfacial Interactions And Dynamic Adhesion Of Synthetic And Living Colloids In Flow, Molly Shave
Doctoral Dissertations
This thesis focuses on the interactions between flowing particles and a surface, where hydrodynamics couples with chemical interactions in order to modify the way they come into play. First this thesis shows how electrostatic chemical heterogeneities on a flowing particle affect the interactions with a wall, using a highly tunable electrostatically heterogenous system produced by adsorbing small amounts of cationic polyelectrolytes onto silica particles in suspension and studying their behavior in flow over the fixed surface. By comparing this behavior to a system with equivalent chemical heterogeneity on a channel wall it was shown that the rotation of a particle …
Thermal Removal Of Carbon Dioxide From The Atmosphere: Energy Requirements And Scaling Issues,
2019
Embry-Riddle Aeronautical University
Thermal Removal Of Carbon Dioxide From The Atmosphere: Energy Requirements And Scaling Issues, Ted Von Hippel
Ted von Hippel
I conduct a systems-level study of direct air capture of CO2 using techniques from thermal physics. This system relies on a combination of an efficient heat exchanger, radiative cooling, and refrigeration, all at industrial scale and operated in environments at low ambient temperatures. While technological developments will be required for such a system to operate efficiently, those developments rest on a long history of refrigeration expertise and technology, and they can be developed and tested at modest scale. I estimate that the energy required to remove CO2 via this approach is comparable to direct air capture by other techniques. The …
Evaluation Of Biodegradability Characteristics Of Cellulose-Based Film As Per Is/Iso 14855-1,
2019
Indian Institute of Packaging, Mumbai
Evaluation Of Biodegradability Characteristics Of Cellulose-Based Film As Per Is/Iso 14855-1, Narayan C. Saha Dr, Gaurav Madhu Dr, Diksha B. Kadu Ms
Journal of Applied Packaging Research
Biodegradable polymers (especially those derived from plant sources) begin their lifecycle as renewable resources, usually in the form of starch or cellulose. In this paper, the evaluation of biodegradability of cellulose-based polymer film under controlled composting conditions as per the guidelines of IS/ISO 14855 (Part-1) standard has been described. Microcrystalline cellulose (MCC) powder was taken as positive-control polymer. The apparatus used to analyse the degree and rate of biodegradation was developed indigenously. The validation of the biodegradability testing apparatus was also performed as per the prescribed test method given in IS/ISO 14855-1.
Synthesis, Characterization And Selected Application Of Chitosan-Coated Magnetic Iron Oxide Nanoparticles,
2019
The British University in Egypt
Synthesis, Characterization And Selected Application Of Chitosan-Coated Magnetic Iron Oxide Nanoparticles, Hany A. Elazab Dr
Chemical Engineering
In this research, we report an efficient method to prepare highly active chitosan-coated magnetic iron oxide nanoparticles by implementing co-precipitation technique which is used for waste water treatment applications. Chitosan-coated magnetic iron oxide nanoparticles were synthesized and characterized using TEM, XRD, and XPS. A comparative study has been made between chitosan powder and chitosan coated with magnetic nanoparticles with respect to the rate of adsorption of copper from aqueous solution. It was also experimentally verified that chitosancoated magnetic iron oxide nanoparticles are much more effective in adsorption of heavy metals than chitosan powder and it takes just few minutes instead …
Synthesis And Characterization Of Dinitro Pentamethylene Tetramine (Dpt),
2019
The British University in Egypt
Synthesis And Characterization Of Dinitro Pentamethylene Tetramine (Dpt), M. M. Seleet, S. A. Hassanien, M. A. Radwan, M. A. Sadek
Chemical Engineering
Preparation of dinitro pentamethylene tetramine (DPT) through the action of nitrating mixture formed of ammonium nitrate and fuming nitric acid on hexamine in presence of acetic acid, acetic anhydride and p-formaldehyde has been carried out. DPT was also prepared from hexamine dinitrate which is an important intermediate appears through preparation of DPT from hexamine directly. Prepared DPT was purified and then characterized through the determination of melting point, element test, FTIR spectrometry, UV spectrometry, and high performance liquid chromatography "HPLC". The obtained results were reliable and consistent with the literature.
Investigation Of The Electrode Polarization Effect For Biosensor Applications,
2019
Southern Methodist University
Investigation Of The Electrode Polarization Effect For Biosensor Applications, Anil Koklu
Mechanical Engineering Research Theses and Dissertations
My research focuses on electrokinetic transport. Particularly, in this dissertation, we focus on fabrication and testing of micro electrodes with nanostructured surfaces to minimize the electrode polarization (EP) effects for biosensor applications. In the first study, electrochemical deposition of gold nanoparticles on to planar gold electrodes was used to generate rough surfaces. Dendritic nanostructures that reduced EP up to two orders of magnitude was obtained by optimizing the deposition conditions. These structures also enhanced dielectrophoresis (DEP) response of our bio-chips, making them usable in physiological buffers. In further studies we discovered a universal scaling of EP in the frequency domain, …
Cellulose Nanofibrils (Cnf) For Textile Applications: Production Of Neat Cnf Filaments And Reinforcement Of Natural Fiber Yarns,
2019
University of Maine
Cellulose Nanofibrils (Cnf) For Textile Applications: Production Of Neat Cnf Filaments And Reinforcement Of Natural Fiber Yarns, Shokoofeh Ghasemi
Electronic Theses and Dissertations
Being the most abundant natural polymer on earth, cellulose materials have been used in many different applications. Cellulose nanofibrils (CNF) are a relatively new group of lignocellulose resource-based nanomaterials and have been the topic of many research efforts in wood products and material science field over the recent years. Using CNF in textile applications is one way to diversify product portfolio of these materials as they contain nanoscale fibrils with high mechanical properties which can fulfil textile industry’s demand for strong natural fibers. Considering that CNF is a wood-based cellulosic material in the form of water suspension, in order to …
Component Analysis And Antiangiogenic Activity Of Thailand Stingless Bee Propolis,
2019
Department of Food and Nutritional Sciences, University of Shizuoka, Shizuoka 424-0414, Japan
Component Analysis And Antiangiogenic Activity Of Thailand Stingless Bee Propolis, Eriko Ishizu, Sari Honda, Tosihro Ohta, Boonyadist Vongsak, Shigenori Kumazawa
Makara Journal of Technology
Propolis is a natural resin produced by honey bees from certain plants, has gained popularity as a food and alternative medicine. However, to the best of our knowledge, few studies on native Thailand stingless bee propolis are available. Information on the chemical composition and biological activities of propolis is needed to investigate its potential utility. Recently we have reported the possible plant origin of Thailand stingless bee propolis, Garcinia mangostana. In this study, further component analysis, functional evaluation, and identification of the plant origin of Thailand stingless bee propolis are conducted. Nine xanthones, including α-mangostin, garcinone C, γ-mangostin, cochinchinone T, …
3d Fdtd Method For Modeling Of Seismo-Electromagnetics Disturbance On Crustal Earth,
2019
Faculty of Engineering and Informatics, Universitas Multimedia Nusantara, Tangerang 15811, Indonesia
3d Fdtd Method For Modeling Of Seismo-Electromagnetics Disturbance On Crustal Earth, Nabila Husna Shabrina, Yasuhide Hobara, Achmad Munir
Makara Journal of Technology
The paper deals with the modelling of seismo-electromagnetics disturbance on the crustal earth by use of threedimensional (3D) finite-difference time-domain (FDTD) method. The model is built up by discretizing the frontier geographical region between Java Island and Sumatra Island in a cylindrical coordinate system-based 3D object. The proposed method is applied to compute and analyze electromagnetics (EM) fields of the observed very low frequency (VLF) wave used for the investigation. Boundary condition of uniaxial perfectly matched layer (UPML) are applied surrounding the area of computation for truncating the object of simulation. The investigation are focused on the propagation time of …
Experimental Evaluation Of Three Different Humidity Conditions To Physical And Mechanical Properties Of Three Different Mixtures Of Unfired Soil Bricks,
2019
Civil Engineering Department, Universitas Indonesia, Depok 16424, Indonesia
Experimental Evaluation Of Three Different Humidity Conditions To Physical And Mechanical Properties Of Three Different Mixtures Of Unfired Soil Bricks, Heru Purnomo, Srikandi Wahyu Arini
Makara Journal of Technology
Unfired brick is considered as a more environmentally friendly material than fired brick. It has lower mechanical properties than that of fired brick where humidity influences both bricks. Physical and mechanical properties of unfired bricks made of three kinds of mixtures were studied experimentally under three humidity conditions. The first kind of unfired brick was made only with soil and water while the second type was made of a mixture of soil, water and lime, and the third type was a mixture of soil, water, lime and uniform treated coir where 4% of lime mass was substituted with coir mass. …
