Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, 2019 University of Connecticut
Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi S. Patel
University Scholar Projects
Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.
Objective: Here, we establish a biodegradable, piezoelectric …
Final Design Report For The Bioburden Pre-Cleaning Device And Dr. Mark Rasnake At The University Of Tennessee Medical Center, 2019 University of Tennessee
Final Design Report For The Bioburden Pre-Cleaning Device And Dr. Mark Rasnake At The University Of Tennessee Medical Center, Katherine Elizabeth Stiles, Megan Pitz, Kayla Franklin, Simran Dayal, Austin Bullock
Chancellor’s Honors Program Projects
No abstract provided.
A Bioinstrumentation Active Learning Educational Module: The Design Of A Working Temperature Sensor Using A Ntc Thermistor, 2019 University of Arkansas, Fayetteville
A Bioinstrumentation Active Learning Educational Module: The Design Of A Working Temperature Sensor Using A Ntc Thermistor, Baylor Bush
Biomedical Engineering Undergraduate Honors Theses
The Department of Biomedical Engineering at the University of Arkansas has continued to develop over the years, with more students enrolling in the program each year. Within the first biomedical engineering course, Introduction to Biomedical Engineering, various topics are introduced to students, and the topic of bioinstrumentation has been one of the most complex and difficult topics for students to comprehend through just a few lectures. In order to aid students in grasping these intricate concepts, an active learning module was developed in which students can work in groups to build a simple thermistor circuit as a temperature sensor. The …
Seeing Eye To Eye: A Machine Learning Approach To Automated Saccade Analysis, 2019 University of Connecticut
Seeing Eye To Eye: A Machine Learning Approach To Automated Saccade Analysis, Maigh Attre
Honors Scholar Theses
Abnormal ocular motility is a common manifestation of many underlying pathologies particularly those that are neurological. Dynamics of saccades, when the eye rapidly changes its point of fixation, have been characterized for many neurological disorders including concussions, traumatic brain injuries (TBI), and Parkinson’s disease. However, widespread saccade analysis for diagnostic and research purposes requires the recognition of certain eye movement parameters. Key information such as velocity and duration must be determined from data based on a wide set of patients’ characteristics that may range in eye shapes and iris, hair and skin pigmentation [36]. Previous work on saccade analysis has …
The Effects Of Bone Morphogenic Protein 2 On The Viability And Proliferation Of Dental Pulp Stem Cell Isolates, 2019 University of Nevada, Las Vegas
The Effects Of Bone Morphogenic Protein 2 On The Viability And Proliferation Of Dental Pulp Stem Cell Isolates, Joseph Cinelli
UNLV Theses, Dissertations, Professional Papers, and Capstones
Growth factor is an umbrella term used to describe a signaling molecule present in organisms that serves the purpose of influencing a stimulatory or inhibitory response from the target cell it acts on. Growth factors are categorized and classified by the types of tissues they act on and the cellular responses they illicit. For example, there are growth factors that act primarily in connective tissue on fibroblasts and they are aptly classified as the fibroblast growth factor family. Similarly, there is another family of growth factors that act on bone forming cells, among others, and they are known as bone …
The Affective Perceptual Model: Enhancing Communication Quality For Persons With Pimd, 2019 University of Nevada, Las Vegas
The Affective Perceptual Model: Enhancing Communication Quality For Persons With Pimd, Jadin Tredup
UNLV Theses, Dissertations, Professional Papers, and Capstones
Methods for prolonged compassionate care for persons with Profound Intellectual and Multiple Disabilities (PIMD) require a rotating cast of import people in the subjects life in order to facilitate interaction with the external environment. As subjects continue to age, dependency on these people increases with complexity of communications while the quality of communication decreases. It is theorized that a machine learning (ML) system could replicate the attuning process and replace these people to promote independence. This thesis extends this idea to develop a conceptual and formal model and system prototype.
The main contributions of this thesis are: (1) proposal of …
Using Peripheral Venous Pressure Waveforms To Predict Key Hemodynamic Parameters, 2019 University of Arkansas, Fayetteville
Using Peripheral Venous Pressure Waveforms To Predict Key Hemodynamic Parameters, Ali Zohair A Alalawi
Graduate Theses and Dissertations
Analysis of peripheral venous pressure (PVP) waveforms is a novel method of monitoring intravascular volume. Two cohorts were used to study the hemodynamics change of the body state and its influence on the PVP using (1) dehydration setting with infants suffering from pyloric stenosis and (2) hemorrhage setting during a craniosynostosis elective surgery. The goal of this research is to develop a minimally invasive method of analyzing the PVP waveforms and find correlations with volume loss.
Twenty-three pyloric stenosis patients PVP were acquired at five stages and were divided into euvolemic, normal fluid volume, and hypovolemic, significant fluid loss. Seven …
Diffuse Reflectance Spectroscopy To Quantify In Vivo Tissue Optical Properties: Applications In Human Epithelium And Subcutaneous Murine Colon Cancer, 2019 University of Arkansas, Fayetteville
Diffuse Reflectance Spectroscopy To Quantify In Vivo Tissue Optical Properties: Applications In Human Epithelium And Subcutaneous Murine Colon Cancer, Gage Joseph Greening
Graduate Theses and Dissertations
Colorectal cancer is the 4th most common and 2nd deadliest cancer. Problems exist with predicting which patients will respond best to certain therapy regimens. Diffuse reflectance spectroscopy has been suggested as a candidate to optically monitor a patient’s early response to therapy and has been received favorably in experimentally managing other cancers such as breast and skin. In this dissertation, two diffuse reflectance spectroscopy probes were designed: one with a combined high-resolution microendoscopy modality, and one that was optimized for acquiring data from subcutaneous murine tumors. For both probes, percent errors for estimating tissue optical properties (reduced scattering coefficient and …
On-Demand Label Production, 2019 California Polytechnic State University, San Luis Obispo
On-Demand Label Production, Robert A. Zimmerman
Master's Theses
The production and approval process for the various labels used in clinical trials wastes significant time and resources through the need to outsource label production or rely on large reams of pre-cut label stock for each revision throughout the process. An in-house, on-demand label printing and cutting system is a potential remedy to this waste. Previous work by Cheadle et al. resulted in a functional electomechanical prototype of the label cutting aspect of this research, capable of rudimentary linear cuts. In this continued research, emphasis was placed on improved label cutting capabilities and creating PC control software for label design. …
Effects Of Ambient And Laser Light On Water Evaporation From The Surface Of Polyurethane Swabs Doped With Surfactant, 2019 University of Arkansas, Fayetteville
Effects Of Ambient And Laser Light On Water Evaporation From The Surface Of Polyurethane Swabs Doped With Surfactant, Collin Campbell
Chemical Engineering Undergraduate Honors Theses
Polyurethane swabs are a common instrument for environmental sampling in the food, medical, and forensic fields due to their high recovery of organisms like viruses, spores, and bacteria. For sampling microbes in food and medical facilities, storage of the collected samples occurs under the absence of light to promote growth for more accurate testing. In the forensic fields, microbial growth results in sample contamination so the inhibition of this growth requires the drying of the swabs. This work studies the evaporation rates of water from polyurethane swabs under zero watt incident light, 30 W fluorescent bulb, 50 mW 532 nm …
Vector Flow Imaging In Pediatric Cardiology - Extracting And Validating Data, 2019 University of Arkansas, Fayetteville
Vector Flow Imaging In Pediatric Cardiology - Extracting And Validating Data, Mason Belue
Biomedical Engineering Undergraduate Honors Theses
In the field of bedside cardiac diagnostic imaging, Doppler Ultrasound (DU) is the gold standard for diagnosing heart conditions. The largest benefit of DU is its ability to noninvasively image cardiac flow and allow the estimation of blood velocity and quantification of anatomical disease. However, to get correct velocity estimation, the position of the transducer in relation to the flow field needs to be known. This is the problem of angle/direction dependency and limits DUs accuracy when imaging in areas where perfect alignment or exact position of the transducer in relation to flow field is not possible or known, such …
Brain Image Clustering By Wavelet Energy And Cbsso Optimization Algorithm, 2019 Department of Mathematics, Ardebil Branch, Islamic Azad University, Ardebil, Iran
Brain Image Clustering By Wavelet Energy And Cbsso Optimization Algorithm, Hasan Hosseinzadeh, Mohammad Sedaghat
Journal of Mind and Medical Sciences
Previously, the diagnosis of brain abnormality was significantly important in the saving of social and hospital resources. Wavelet energy is known as an effective feature detection which has great efficiency in different utilities. This paper suggests a new method based on wavelet energy to automatically classify magnetic resonance imaging (MRI) brain images into two groups (normal and abnormal), utilizing support vector machine (SVM) classification based on chaotic binary shark smell optimization (CBSSO) to optimize the SVM weights.
The results of the suggested CBSSO-based KSVM are compared favorably to several other methods in terms of better sensitivity and authenticity. The proposed …
Development Of A Force-Based Ream Vector Measurement System For Glenoid Reaming Simulation, 2019 The University of Western Ontario
Development Of A Force-Based Ream Vector Measurement System For Glenoid Reaming Simulation, David Axford
Electronic Thesis and Dissertation Repository
Glenoid reaming is a technically challenging step during total shoulder arthroplasty surgery that may be improved through frequent practice and exposure to simulation training. At our institution, a vibration haptic glenoid reaming simulator is being developed that simulates the vibrations felt during glenoid reaming. This thesis presents the development of a force-based reamer vector measurement system that allows the simulator to measure the user’s net applied force and reamer angle of approach. This capability allows for the simulation of eccentric reaming maneuvers commonly used to adjust the glenoid orientation. The system error was characterized and evaluated using a robot to …
The Modeling, Design, Fabrication, And Application Of Biosensor Based On Electric Cell-Substrate Impedance Sensing (Ecis) Technique In Environmental Monitoring, 2019 CUNY Graduate Center
The Modeling, Design, Fabrication, And Application Of Biosensor Based On Electric Cell-Substrate Impedance Sensing (Ecis) Technique In Environmental Monitoring, Xudong Zhang, William Wang, Sunghoon Jang
Publications and Research
In this research, the modeling, design, fabrication, and application of ECIS sensors in environmental monitoringare studied. The ECIS sensors are able to qualify the water toxicity through measuring the cell impedance. A novel mathematical model is proposed to analyze the distribution of electric potential and current of ECIS. This mathematical model is validated by experimental data and can be used to optimize the dimension of ECIS electrodes in order to satisfy environmental monitors. The detection sensitivity of ECIS sensors is analyzed by the mathematical model and experimental data. The simulated and experimental results show that ECIS sensors with smaller radius …
System Fault Tolerancing And Self-Reported Usability Of A Closed-Loop Robotic System For Reading Comprehension Skill Development In Children Who Are Deaf Or Hard Of Hearing, 2019 University of Tennessee
System Fault Tolerancing And Self-Reported Usability Of A Closed-Loop Robotic System For Reading Comprehension Skill Development In Children Who Are Deaf Or Hard Of Hearing, Miroslava I. Migovich
EURēCA: Exhibition of Undergraduate Research and Creative Achievement
Children who are deaf or hard of hearing often suffer from low literacy and reading comprehension rates [1]. Over the past 50 years, research had concluded that literacy rates for these children rarely pass a fourth-grade level [2]. However, little research has been done regarding interventions for reading comprehension skill development [3]. Our long-term study seeks to incorporate social robotics and reading comprehension development to provide an option for in-home and in-school reading focused interventions. In the current study, we present an initial validation of a closed-loop social robotic system for reading comprehension testing. Results suggest our robot-based system is …
An Arm And A Leg: Medtech Perspectives On Human-Centered Design, 2019 Brigham Young University
An Arm And A Leg: Medtech Perspectives On Human-Centered Design, Evan D. Poff
Marriott Student Review
The art of human-centered design accounts for both technological and emotional specifications in order to deliver meaningful products that meet the specific needs of the individual customer. Every business professional can deepen his or her understanding of human-centered design – regardless of our industry of choice – by looking to perspectives that the business of medical technology offers. To that end, this article draws upon interviews with three figures in this remarkable field, distilling their insights on how to cultivate businesses that produce human-centered solutions.
Tissue Equivalent Gellan Gum Gel Materials For Clinical Mri And Radiation Dosimetry, 2019 The University of Western Ontario
Tissue Equivalent Gellan Gum Gel Materials For Clinical Mri And Radiation Dosimetry, Pawel Brzozowski
Electronic Thesis and Dissertation Repository
Hydrogels contain high amount of water allowing their use as surrogates to human tissues with specific properties that can be tuned by additives. Gellan gum is a gel-forming material of interest and is a replacement for other common gelling agent with limited use as a tissue phantom. Therefore, this thesis examines the application of gellan gum gels as a novel magnetic resonance imaging (MRI) phantom with a design of experiments model to obtain tunable properties. The analysis was extended to include mechanical and electrical properties with a separate design of experiment. Gels doped with synthesized superparamagnetic iron oxide nanoparticles (SPIONs) …
Advantages Of Air Cooling In Thermal Ablation, 2019 Kansas State University Libraries
Advantages Of Air Cooling In Thermal Ablation, Alexander Sheikh
Kansas State University Undergraduate Research Conference
Advantages of Air Cooling in Thermal Ablation
Alex Sheikh, Dr. Punit Prakash, Hojjat Fallahi
Department of Electrical and computer Engineering
Thermal ablation is the method of destroying tumors through the application of extreme temperatures. For this experiment, heat is used and supplied by an amplifier/power generator. The heat is transported out through a catheter device and into the designated area of the tumor. Cooling the tip of the device can be used to control this heat in effort to expand the ablation size and cut down on the destruction of unwanted tissue. Thus far, water has been the primary strategy …
Suture-Less Trocar Site Closure Clip, 2019 University of Louisville
Suture-Less Trocar Site Closure Clip, Hares A. Patel
Electronic Theses and Dissertations
Introduction: Following laparoscopic surgery, there is a need, in many cases, to close trocar sites to prevent hernias. Currently, devices that exist on the market are suture based, but the lack of standardization in the suturing techniques together with the time-consuming nature of the procedure leads to the need for improvement in trocar site closure products. Trocar closure sites do not need to be fully closed on the fascial layer; rather, sufficiently blocking the hole at the abdominal wall can significantly reduce post-operative herniation. A retrospective study on trocar site herniation (TSH) after laparoscopic surgery indicates a TSH incidence …
Direct Printing/Patterning Of Key Components For Biosensor Devices, 2019 University of Massachusetts Amherst
Direct Printing/Patterning Of Key Components For Biosensor Devices, Yiliang Zhou
Doctoral Dissertations
Recently, biosensor devices, especially wearable devices for monitoring human health, have attracted significant interests and meanwhile, they have a huge market. These wearable biosensor devices usually consist of several key components, including microfluidics, biosensing elements and power supply. Though advanced sensing platforms have been extensively explored, high manufacturing fee and lack of practical functions are the main reasons that most of devices and techniques are still out of reach for potential users. This dissertation focuses on fabricating these key components for biosensor devices via advanced printing/patterning techniques, such as inkjet-printing and nanoimprinting. These fabrication techniques can be potentially extended to …