Developing Chitosan-Based Biomaterials For Brain Repair And Neuroprosthetics,
2010
Department of Materials Science and Engineering, UTK
Developing Chitosan-Based Biomaterials For Brain Repair And Neuroprosthetics, Zheng Cao
Masters Theses
Chitosan is widely investigated for biomedical applications due to its excellent properties, such as biocompatibility, biodegradability, bioadhesivity, antibacterial, etc. In the field of neural engineering, it has been extensively studied in forms of film and hydrogel, and has been used as scaffolds for nerve regeneration in the peripheral nervous system and spinal cord. One of the main issues in neural engineering is the incapability of neuron to attach on biomaterials. The present study, from a new aspect, aims to take advantage of the bio-adhesive property of chitosan to develop chitosan-based materials for neural engineering, specifically in the fields of brain …
Synthesis Of An Endothelial Cell Mimicking Surface Containing Thrombomodulin And Endothelial Protein C Receptor,
2010
University of Nebraska at Lincoln
Synthesis Of An Endothelial Cell Mimicking Surface Containing Thrombomodulin And Endothelial Protein C Receptor, Karl E. Kador
Chemical & Biomolecular Engineering Theses, Dissertations, & Student Research
Synthetic materials for use in blood contacting applications have been studied for many years with limited success. One of the main areas of need for these materials is the design of synthetic vascular grafts for use in the hundreds of thousands of patients who have coronary artery bypass grafting, many without suitable veins for autologous grafts. The design of these grafts is constrained by two common modes of failure, the formation of intimal hyperplasia (IH) and thrombosis. IH formation has been previously linked to a mismatching of the mechanical properties of the graft and has been overcome by creating grafts …
Microstructural Characteristics Of Functionally Graded Materials Designed As Dental Post,
2010
Department of Conservative Dentistry, Faculty of Dentistry, University of Thamar, Thamar, Yemen
Microstructural Characteristics Of Functionally Graded Materials Designed As Dental Post, Ahmed A. Madfa
Ahmed A. Madfa
To study the interfaces and microstructure of multilayered materials fabricated based on functionally graded concept for use as dental posts.
,
2010
University of Nebraska-Lincoln
, Geun-Cheol Gil, William H. Velander, Kevin E. Van Cott
Kevin Van Cott Publications
Human protein C (hPC) is glycosylated at three Asn-X-Ser/Thr and one atypical Asn-X-Cys sequons. We have characterized the micro- and macro-heterogeneity of plasma-derived hPC and compared the glycosylation features with recombinant protein C (tg-PC) produced in a transgenic pig bioreactor from two animals having approximately tenfold different expression levels. The N-glycans of hPC are complex di- and tri-sialylated structures, and we measured 78% site occupancy at Asn-329 (the Asn-X-Cys sequon). The N-glycans of tg-PC are complex sialylated structures, but less branched and partially sialylated. The porcine mammary epithelial cells glycosylate the Asn-X-Cys sequon with a similar efficiency as human hepatocytes …
New Generation Of The Dental Posts For Endodontic Application.,
2010
Department of Conservative Dentistry, Faculty of Dentistry, University of Thamar, Thamar, Yemen
New Generation Of The Dental Posts For Endodontic Application., Ahmed A. Madfa
Ahmed A. Madfa
Fabricated multilayer dental post with the functionally graded design is a novel product that exhibits graded properties varied from coronal to apical parts of the tooth. The new dental post definitely performs better than posts available in the market and improves the quality of human life
Destruction Of Α -Synuclein Based Amyloid Fibrils By A Low Temperature Plasma Jet,
2010
Old Dominion University
Destruction Of Α -Synuclein Based Amyloid Fibrils By A Low Temperature Plasma Jet, Erdinc Karakas, Agatha Munyanyi, Lesley Greene, Mounir Laroussi
Electrical & Computer Engineering Faculty Publications
Amyloid fibrils are ordered beta-sheet aggregates that are associated with a number of neurodegenerative diseases such as Alzheimer and Parkinson. At present, there is no cure for these progressive and debilitating diseases. Here we report initial studies that indicate that low temperature atmospheric pressure plasma can break amyloid fibrils into smaller units in vitro. The plasma was generated by the plasma pencil, a device capable of emitting a long, low temperature plasma plume/jet. This avenue of research may facilitate the development of a plasma-based medical treatment.
Influence Of Compressible Aerogel Electrodes On The Properties Of An Electrochemical Cell,
2010
University of Denver
Influence Of Compressible Aerogel Electrodes On The Properties Of An Electrochemical Cell, Chris Sponheimer
Electronic Theses and Dissertations
In the biomedical field the need for intra organ pressure measurement can only be facilitated by adapting existing pressure sensing technology to the specific tissues under test. The customization of these sensors has only driven up cost and the need to explore new technologies has become increasingly more important. For this dissertation, we explore the use of a new technology, particularly electrochemical pressure sensing to provide a low-cost pressure sensor to fill this need. Preliminary testing showed that electrically conductive polymers exhibited a change in voltage when pressurized if bubbles were first electrolyzed in the gel creating an aerogel, and …
